2025
Accelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers
Abraham S, Parekh J, Lee S, Afrin H, Rozenblit M, Blenman K, Perry R, Ferrucci L, Liu J, Irwin M, Lustberg M. Accelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers. Cancer Medicine 2025, 14: e70929. PMID: 40322791, PMCID: PMC12051034, DOI: 10.1002/cam4.70929.Peer-Reviewed Original ResearchConceptsBiological age of patientsLeukocyte telomere lengthInterleukin-6Treatment-related toxicityAge of patientsTherapy-induced toxicityExpression of p16INK4aPredictors of toxicityStatus of biomarkersMarkers of cellular senescenceRadiation therapyBiological ageCancer patientsCancer therapyFunctional reserveAging biomarkersPhysiological reserveCancer treatmentCancerConfirmatory studiesTherapyClinical practiceFunctional capacityPatientsFunctional status
2024
Exercise and Nutrition to Improve Cancer Treatment-Related Outcomes (ENICTO)
Schmitz K, Brown J, Irwin M, Robien K, Scott J, Berger N, Caan B, Cercek A, Crane T, Evans S, Ligibel J, Meyerhardt J, Agurs-Collins T, Basen-Engquist K, Bea J, Cai S, Cartmel B, Chinchilli V, Demark-Wahnefried W, Dieli-Conwright C, DiPietro L, Doerksen S, Edelstein S, Elena J, Evans W, Ferrucci L, Foldi J, Freylersythe S, Furberg H, Jones L, Levine R, Moskowitz C, Owusu C, Penedo F, Rabin B, Ratner E, Rosenzweig M, Salz T, Sanft T, Schlumbrecht M, Spielmann G, Thomson C, Tjaden A, Weiser M, Yang S, Yu A, Perna F, Caan B, Anderson S, Bahia H, Castillo A, Feliciano E, Johnson K, Ross M, Weltzein E, Brown J, Albarado B, Compton S, Green T, Nash R, Nauta P, Welch M, Yang S, Meyerhardt J, Dieli-Conwright C, Nguyen D, Pena A, Spielmann G, Kim Y, Evans W, Bea J, Blew R, Crane T, Bhatti A, Clavon R, Erlandsen S, Freylersythe S, Hollander K, Lopez-Pentecost M, Penedo F, Rolle L, Rossi P, Schlumbrecht M, Wheeler M, Irwin M, Cao A, Cartmel B, Ferrucci L, Gottlieb L, Harrigan M, Li F, McGowan C, Puklin L, Ratner E, Sanft T, Zupa M, Berger N, Cerne S, Mills C, Conochan S, Hundal J, Owusu C, Ligibel J, Campbell N, DiGuglielmo K, Kemp W, Maples-Campbell C, Nguyen T, Oppenheim J, Tanasijevic A, Thomson C, Yung A, Basen-Engquist K, Loomba P, Chinchilli V, Schmitz K, Binder J, Doerksen S, Foldi J, Garrett S, Scalise R, Sobolewski M, White L, Scott J, Cercek A, Cai S, Cao S, Furberg H, Harrison J, Jones L, Lee C, Levine R, Michalski M, Moskowitz C, Novo R, Rabazzi J, Stoeckel K, Salz T, Weiser M, Yu A, Demark-Wahnefried W, Robien K, Evans S, DiPietro L, Duong B, Edelstein S, Helmchen L, Le D, McCleary C, Tjaden A, Wopat H, Rabin B, Perna F, Agurs-Collins T, Czajkowski S, Elena J, Nebeling L, Norton W. Exercise and Nutrition to Improve Cancer Treatment-Related Outcomes (ENICTO). Journal Of The National Cancer Institute 2024, 117: 9-19. PMID: 39118255, PMCID: PMC11717426, DOI: 10.1093/jnci/djae177.Peer-Reviewed Original ResearchSelf-reported physical functionTreatment-related outcomesTreatment-related side effectsRisk of suboptimal outcomesExercise interventionOncology carePhysical functionNational Cancer InstituteNutrition ProgramIntervention effectsCommon data elementsExerciseCancer InstituteCommunity opportunitiesData elementsStandard of careInterventionCareCancer patientsNutritionRelative dose intensityOutcomesSuboptimal outcomesCancer treatmentChemotherapy relative dose intensity
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