2025
Diet and Prevention of Cardiovascular Disease and Cancer JACC: CardioOncology State-of-the-Art Review
Hull S, Mszar R, Ostfeld R, Ferrucci L, Mucci L, Giovannucci E, Loeb S. Diet and Prevention of Cardiovascular Disease and Cancer JACC: CardioOncology State-of-the-Art Review. JACC CardioOncology 2025 PMID: 40879583, DOI: 10.1016/j.jaccao.2025.07.008.Peer-Reviewed Original ResearchPrevention of cardiovascular diseaseCardiovascular diseaseCardiovascular disease mortalityIntake of red meatLeading risk factorUltraprocessed foodsHealthy choicesImplementation scienceLifestyle factorsPoor dietExcessive intakeStandard American dietRed meatLife expectancyRisk factorsPathophysiology of cardiovascular diseaseAmerican dietPreventionUnited StatesTrial dataMortalityCancerLifestyleSmokingDietAddressing conceptual and design gaps in the oncology nutrition evidence base during chemotherapy: contributions of the Exercise and Nutrition Interventions to Improve Cancer Treatment-Related Outcomes Consortium
Compton S, Wopat H, Lopez-Pentecost M, Agurs-Collins T, Brown J, Caan B, Demark-Wahnefried W, Elena J, Ferrucci L, McGowan C, Puklin L, Schmitz K, Thomson C, Robien K, Crane T, Caan B, Anderson S, Bahia H, Castillo A, Feliciano E, Johnson K, Ross M, Weltzein E, Brown J, Compton S, Green T, Nauta P, Yang S, Meyerhardt J, Dieli-Conwright C, Nguyen D, Pena A, Spielmann G, Kim Y, Evans W, Bea J, Blew R, Thomson C, Crane T, Camacho V, Cespedes V, Erlandsen S, Freylersythe S, Hollander K, Lopez-Pentecost M, Penedo F, Rolle L, Rossi P, Schlumbrecht M, Wheeler M, Irwin M, Cao A, Cartmel B, Ferrucci L, Gottlieb L, Harrigan M, Li F, McGowan C, Puklin L, Elena R, Sanft T, Zupa M, Berger N, Cerne S, Mills C, Conochan S, Hundal J, Owusu C, Pink J, Ligibel J, Campbell N, DiGuglielmo K, Kemp W, Maples-Campbell C, Nguyen T, Oppenheim J, Tanasijevic A, Thomson C, Yung A, Basen-Engquist K, Loomba P, Chinchilli V, Schmitz K, Binder J, Doerksen S, Foldi J, Garrett S, Scalise R, Sobolewski M, Scott J, Cercek A, Cai S, Cao S, Furberg H, Harrison J, Jones L, Lee C, Levine R, Michalski M, Moskowitz C, Meara A, Rabazzi J, Stoeckel K, Salz T, Weiser M, Yu A, Demark-Wahnefried W, Robien K, Evans S, DiPietro L, Duong B, Edelstein S, Helmchen L, Le D, McCleary C, Tjaden A, Wopat H, Rabin B, Perna F, Agurs-Collins T, Czajkowski S, Elena J, Nebeling L, Norton W. Addressing conceptual and design gaps in the oncology nutrition evidence base during chemotherapy: contributions of the Exercise and Nutrition Interventions to Improve Cancer Treatment-Related Outcomes Consortium. Journal Of The National Cancer Institute 2025, djaf143. PMID: 40680173, DOI: 10.1093/jnci/djaf143.Peer-Reviewed Original ResearchNutritional interventionPractice guidelinesNutrition practice guidelinesActive cancer treatmentDevelopment of practice guidelinesScientific rigor of researchNutrition evidence baseNutritional assessment toolCancer continuumScientific rigorCancer preventionTreatment-related outcomesLong-term survivorshipEvidence baseAssessment toolInterventionExerciseRigor of researchConceptual frameworkCancer treatmentResearch ConsortiumNutritionCompletion of chemotherapyGuidelinesCancerAccelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers
Abraham S, Parekh J, Lee S, Afrin H, Rozenblit M, Blenman K, Perry R, Ferrucci L, Liu J, Irwin M, Lustberg M. Accelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers. Cancer Medicine 2025, 14: e70929. PMID: 40322791, PMCID: PMC12051034, DOI: 10.1002/cam4.70929.Peer-Reviewed Original ResearchConceptsBiological age of patientsLeukocyte telomere lengthInterleukin-6Treatment-related toxicityAge of patientsTherapy-induced toxicityExpression of p16INK4aPredictors of toxicityStatus of biomarkersMarkers of cellular senescenceRadiation therapyBiological ageCancer patientsCancer therapyFunctional reserveAging biomarkersPhysiological reserveCancer treatmentCancerConfirmatory studiesTherapyClinical practiceFunctional capacityPatientsFunctional status
2023
Structural Racism, Lifestyle Behaviors, and Obesity-related Cancers among Black and Hispanic/Latino Adults in the United States: A Narrative Review.
Pichardo M, Ferrucci L, Molina Y, Esserman D, Irwin M. Structural Racism, Lifestyle Behaviors, and Obesity-related Cancers among Black and Hispanic/Latino Adults in the United States: A Narrative Review. Cancer Epidemiology Biomarkers & Prevention 2023, 32: 1498-1507. PMID: 37650844, PMCID: PMC10872641, DOI: 10.1158/1055-9965.epi-22-1147.Peer-Reviewed Original ResearchConceptsHispanic/Latino adultsObesity-related cancersLifestyle behaviorsLatino adultsLifestyle guidelinesCancer preventionPoor lifestyle behaviorsU.S. Hispanic/Latino adultsHealthful lifestyle behaviorsCause of deathHealthy lifestyle choicesChronic diseasesCardiovascular diseaseCommon causeCancer riskNarrative reviewBlack adultsDisproportionate burdenObesityCancerAdultsLifestyle choicesDiseasePreventionDeathA review of the impact of energy balance on triple-negative breast cancer
Akingbesote N, Owusu D, Liu R, Cartmel B, Ferrucci L, Zupa M, Lustberg M, Sanft T, Blenman K, Irwin M, Perry R. A review of the impact of energy balance on triple-negative breast cancer. JNCI Monographs 2023, 2023: 104-124. PMID: 37139977, DOI: 10.1093/jncimonographs/lgad011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTriple-negative breast cancerInterventional studyBreast cancerCancer treatmentClinical interventional studyClinical observationalImmune activationCancer outcomesCancer careClinical studiesOverall healthEnergy intakeNarrative reviewCancer cellsEnergy expenditureCancerTreatmentEnergy balanceOutcomesExerciseReviewDetrimental effectsImmunotherapyStudyIntakeA qualitative study identifying challenges resulting from complex evidence on lifestyle factors and cancer: perspectives from Black and Latina cancer survivors and healthcare providers
Pichardo M, Irwin M, Sanft T, Ferrucci L, Ginader A, Nguyen T, Esserman D, Cartmel B, Molina Y. A qualitative study identifying challenges resulting from complex evidence on lifestyle factors and cancer: perspectives from Black and Latina cancer survivors and healthcare providers. Supportive Care In Cancer 2023, 31: 111. PMID: 36633678, PMCID: PMC9912693, DOI: 10.1007/s00520-022-07539-9.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsOncology healthcare providersCancer survivorsLifestyle behaviorsHealthcare providersGeneric messagingEvidence-based knowledgeFemale breast cancer survivorsHealthcare provider counselingHealthy lifestyle guidelinesPatient-level barriersHealthy lifestyle behaviorsLifestyle guidelinesProvider counselingLifestyle factorsOncology careCancer outcomesBreast cancerConsistency of evidenceCurrent evidenceAvailable evidenceSurvivorsCancer diagnosisLevel barriersCancer
2010
Meat and components of meat and the risk of bladder cancer in the NIH‐AARP Diet and Health Study
Ferrucci LM, Sinha R, Ward MH, Graubard BI, Hollenbeck AR, Kilfoy BA, Schatzkin A, Michaud DS, Cross AJ. Meat and components of meat and the risk of bladder cancer in the NIH‐AARP Diet and Health Study. Cancer 2010, 116: 4345-4353. PMID: 20681011, PMCID: PMC2936663, DOI: 10.1002/cncr.25463.Peer-Reviewed Original ResearchConceptsNIH-AARP DietBladder cancerHazard ratioDietary nitriteBladder carcinogenesisHealth StudyProspective NIH-AARP DietRed meatFood frequency questionnaireConfidence intervalsBladder cancer casesHeterocyclic aminesIntake of nitratePositive associationDietary nitrateNitrite intakeCancerTop quintileComponents of meatRiskIntakeCarcinogenesisAssociationDiet
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