2025
Receipt of addiction treatment after nonfatal opioid overdose and risk of subsequent overdose: A retrospective cohort study
Howell B, Black A, Lin H, Liberatore M, Greene C, D'Onofrio G, Heimer R, Grau L, Hawk K, Fiellin D, Becker W. Receipt of addiction treatment after nonfatal opioid overdose and risk of subsequent overdose: A retrospective cohort study. Drug And Alcohol Dependence 2025, 273: 112679. PMID: 40413965, PMCID: PMC12178112, DOI: 10.1016/j.drugalcdep.2025.112679.Peer-Reviewed Original ResearchConceptsAddiction treatment modalitiesAddiction treatmentInpatient addiction treatmentOpioid overdose survivorsOverdose survivorsOpioid agonist treatmentOpioid overdoseReceipt of methadoneOpioid withdrawalInpatient treatmentBenzodiazepine exposureNon-medicalAddictionAssociated with reduced riskNonfatal opioid overdoseAgonist treatmentNon-fatal opioid overdoseTreatment modalitiesAssociated with increased riskBenzodiazepinesIndividual level dataMethadoneRetrospective cohort studyOpioidBuprenorphineSpatial associations between alcohol detection in opioid overdose deaths and alcohol outlets
Viera A, Heimer R, Grau L. Spatial associations between alcohol detection in opioid overdose deaths and alcohol outlets. Drug And Alcohol Dependence 2025, 271: 112659. PMID: 40184870, PMCID: PMC12050193, DOI: 10.1016/j.drugalcdep.2025.112659.Peer-Reviewed Original ResearchConceptsOff-premise alcohol outletsNearest alcohol outletAlcohol outletsOpioid overdose deathsSpatial distribution of alcohol outletsSubstance use patternsDistribution of alcohol outletsDensity of alcohol outletsOverdose deathsDepressive effects of opioidsAlcohol outlet densityEffects of opioidsCensus tract levelAssociated with increased oddsOverdose riskCentral nervous systemOutlet densityTract levelCensus tractsDepressant effectCommunity investmentOpioidSocial vulnerabilityAlcoholNervous system
2024
Prescription Opioid Dose Change Before Fatal Opioid-Detected Overdose.
Kazemitabar M, Howell B, Becker W, Lin H, Grau L, Heimer R, D'Onofrio G, Hawk K, Fiellin D, Black A. Prescription Opioid Dose Change Before Fatal Opioid-Detected Overdose. Journal Of Studies On Alcohol And Drugs 2024, 85: 815-819. PMID: 38775307, DOI: 10.15288/jsad.24-00026.Peer-Reviewed Original ResearchPrescribed opioidsOpioid dose changesRapid dose increaseNon-HispanicOverdose deathsToxicological resultsNon-prescription opioidsBlack non-HispanicMorphine equivalentsOpioid therapyWhite non-HispanicDose changesDaily doseMean ageDispensed opioidsPrescription opioidsPrescribing patternsOpioidDose increaseOpioid overdose crisisIncreasing dosesStudy investigated patternsEffect of timeEffects of ageSecondary analysis
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