2025
Incidence of Frailty, Dementia, and Disability Among Community‐Living Older Americans According to County‐Level Disadvantage
Wang Y, Zang E, Davis‐Plourde K, Vander Wyk B, Gill T, Becher R. Incidence of Frailty, Dementia, and Disability Among Community‐Living Older Americans According to County‐Level Disadvantage. Journal Of The American Geriatrics Society 2025, 73: 1847-1856. PMID: 40196885, PMCID: PMC12213133, DOI: 10.1111/jgs.19465.Peer-Reviewed Original ResearchConceptsNational Health and Aging Trends StudyActivities of daily living disabilityActivities of daily livingIncidence of frailtySocial determinants of healthOlder personsOlder AmericansContextual disadvantageAge- and sex-adjusted HRDisadvantaged countiesDeterminants of healthSex-adjusted HRNationally representative longitudinal studyRepresentative longitudinal studyCommunity-livingDaily livingClinically Meaningful OutcomesTrends StudyGeriatric conditionsNo prior studiesNational incidenceIncidence rateDementiaFrailtyCounty-level
2024
National Estimates of Short- and Longer-Term Hospital Readmissions After Major Surgery Among Community-Living Older Adults
Wang Y, Leo-Summers L, Vander Wyk B, Davis-Plourde K, Gill T, Becher R. National Estimates of Short- and Longer-Term Hospital Readmissions After Major Surgery Among Community-Living Older Adults. JAMA Network Open 2024, 7: e240028. PMID: 38416499, PMCID: PMC10902728, DOI: 10.1001/jamanetworkopen.2024.0028.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCohort StudiesDementiaFemaleFrailtyHumansLongitudinal StudiesMaleMedicare Part CPatient ReadmissionProspective StudiesUnited StatesConceptsCenters for Medicare & Medicaid ServicesFee-for-serviceMedicare Advantage beneficiariesHospital readmissionUS residentsNational Health and Aging Trends Study dataCommunity-living older adultsProspective longitudinal cohort studyCommunity-living participantsRate of hospital readmissionLikelihood of hospital readmissionPopulation-based estimatesNationally representative estimatesSex-adjusted modelsCommunity-livingData linkageGeriatric conditionsMedicaid ServicesOlder personsOlder adultsMain OutcomesNational estimatesRepresentative estimatesData analysisCohort study
2022
Joint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias
Davis-Plourde KL, Mayeda ER, Lodi S, Filshtein T, Beiser A, Gross AL, Seshadri S, Glymour MM, Tripodis Y. Joint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias. Epidemiology 2022, 33: 362-371. PMID: 35383644, DOI: 10.1097/ede.0000000000001472.Peer-Reviewed Original ResearchConceptsCognitive declineSurvival biasCox proportional hazards modelHazard of mortalityProportional hazards modelExposure of interestEffect of educationEffects of exposureHazards modelDementia diagnosisAlzheimer's diseaseMixed-effects modelsGEE modelMortalitySurvivalInconsistent resultsDiseaseInformative attritionStudy dataAttrition weightsExposure
2021
Aortic stiffness and cerebral microbleeds: The Framingham Heart Study
Romero JR, Himali JJ, Beiser A, Pase MP, Davis-Plourde KL, Parva P, Seshadri S, Mitchell GF. Aortic stiffness and cerebral microbleeds: The Framingham Heart Study. Vascular Medicine 2021, 26: 312-314. PMID: 33393444, DOI: 10.1177/1358863x20979740.Peer-Reviewed Original Research
2019
Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume
Spartano NL, Davis-Plourde KL, Himali JJ, Andersson C, Pase MP, Maillard P, DeCarli C, Murabito JM, Beiser AS, Vasan RS, Seshadri S. Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume. JAMA Network Open 2019, 2: e192745. PMID: 31002329, PMCID: PMC6481600, DOI: 10.1001/jamanetworkopen.2019.2745.Peer-Reviewed Original ResearchMeSH KeywordsAccelerometryAgedBrainCross-Sectional StudiesDementiaExerciseFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleOrgan SizeConceptsLight-intensity physical activityTotal brain volumeHigher total brain volumeMagnetic resonance imagingPA guidelinesPhysical activityBrain volumeBrain agingVigorous PA levelsCommunity-based cohort studyPA levelsBrain magnetic resonance imagingAssociation of accelerometerCurrent PA guidelinesBrain MRI measuresFramingham Heart Study participantsVigorous physical activityAdditional hourMost older adultsFramingham Heart StudyHigher brain volumesCohort studyDementia preventionDementia riskMean age
2018
Vascular risk at younger ages most strongly associates with current and future brain volume.
Pase MP, Davis-Plourde K, Himali JJ, Satizabal CL, Aparicio H, Seshadri S, Beiser AS, DeCarli C. Vascular risk at younger ages most strongly associates with current and future brain volume. Neurology 2018, 91: e1479-e1486. PMID: 30232248, PMCID: PMC6202941, DOI: 10.1212/wnl.0000000000006360.Peer-Reviewed Original ResearchConceptsVascular risk factor burdenRisk factor burdenVascular risk factorsLower brain volumeRisk factorsStrength of associationBrain volumeYounger ageAge decadeFramingham Stroke Risk ProfileAge 45 yearsPotential therapeutic effectsStroke Risk ProfileLongitudinal analysisFramingham Heart StudyCross-sectional analysisStroke riskVascular riskDementia riskAge 45Therapeutic effectHeart StudyRisk profileBrain structuresCross-sectional data
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply