2023
Prioritizing persons deprived of liberty in global guidelines for tuberculosis preventive treatment
Narayan A, Salindri A, Keshavjee S, Muyoyeta M, Velen K, Rueda Z, Croda J, Charalambous S, García-Basteiro A, Shenoi S, Gonçalves C, da Silva L, Possuelo L, Aguirre S, Estigarribia G, Sequera G, Grandjean L, Telisinghe L, Herce M, Dockhorn F, Altice F, Andrews J. Prioritizing persons deprived of liberty in global guidelines for tuberculosis preventive treatment. PLOS Medicine 2023, 20: e1004288. PMID: 37788448, PMCID: PMC10547494, DOI: 10.1371/journal.pmed.1004288.Peer-Reviewed Original ResearchGlobal, regional, and national estimates of tuberculosis incidence and case detection among incarcerated individuals from 2000 to 2019: a systematic analysis
Martinez L, Warren J, Harries A, Croda J, Espinal M, Olarte R, Avedillo P, Lienhardt C, Bhatia V, Liu Q, Chakaya J, Denholm J, Lin Y, Kawatsu L, Zhu L, Horsburgh C, Cohen T, Andrews J. Global, regional, and national estimates of tuberculosis incidence and case detection among incarcerated individuals from 2000 to 2019: a systematic analysis. The Lancet Public Health 2023, 8: e511-e519. PMID: 37393090, PMCID: PMC10323309, DOI: 10.1016/s2468-2667(23)00097-x.Peer-Reviewed Original ResearchConceptsTuberculosis incidenceCase detection ratioIncidence rateCase detectionHigh tuberculosis incidence ratesGlobal tuberculosis control effortsIncident tuberculosis casesTuberculosis incidence rateIncarcerated individualsTuberculosis control effortsTuberculosis case detectionTuberculosis casesNotification ratesNational incidenceTuberculosis notificationsGlobal incidenceHigh riskPrevalence estimatesNational estimatesWHO regionsIncidenceStudy periodMeta-regression frameworkTuberculosisNational InstituteUse of rapid molecular TB diagnostics for incarcerated people in Brazil
Fajer E, Costa F, Pelissari D, Quijano F, de Brito A, Cunha E, Croda J, Andrews J, Walter K. Use of rapid molecular TB diagnostics for incarcerated people in Brazil. The International Journal Of Tuberculosis And Lung Disease 2023, 27: 416-418. PMID: 37143225, PMCID: PMC10171485, DOI: 10.5588/ijtld.22.0642.Peer-Reviewed Original ResearchScaling up evidence-based approaches to tuberculosis screening in prisons
Charalambous S, Velen K, Rueda Z, Croda J, Herce M, Shenoi S, Altice F, Muyoyeta M, Telisinghe L, Grandjean L, Keshavjee S, Andrews J. Scaling up evidence-based approaches to tuberculosis screening in prisons. The Lancet Public Health 2023, 8: e305-e310. PMID: 36780916, DOI: 10.1016/s2468-2667(23)00002-6.Commentaries, Editorials and LettersConceptsIncidence of tuberculosisCase-finding strategyHigh tuberculosis burdenMinistry of HealthEvidence-based approachTuberculosis burdenTreatment cascadeTuberculosis screeningTuberculosis notificationsTuberculosis diagnosisGeneral populationCare programDiagnostic strategiesTuberculosisEvidence baseSystematic screeningHigh rateIncidenceScreeningSettingSpread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study
Busatto C, Possuelo L, Bierhals D, de Oliveira C, de Souza M, Fanfa D, Barreto É, Schwarzbold P, Von Groll A, Portugal I, Perdigão J, Croda J, Andrews J, da Silva P, Ramis I. Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study. European Journal Of Clinical Microbiology & Infectious Diseases 2023, 42: 297-304. PMID: 36701032, DOI: 10.1007/s10096-023-04546-4.Peer-Reviewed Original ResearchConceptsAnti-TB drug resistanceM. tuberculosisTB control programsCross-sectional studyM. tuberculosis strainsMolecular epidemiology studiesTB burdenLAM strainsTuberculosis strainsEpidemiology studiesDrug resistanceMycobacterium tuberculosisCentral laboratoryTranslational researchTuberculosisCommon strainControl programsPDLMolecular characterizationHaarlemImproved strategiesPersonsPhylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay
Sanabria G, Sequera G, Aguirre S, Méndez J, dos Santos P, Gustafson N, Godoy M, Ortiz A, Cespedes C, Martínez G, García-Basteiro A, Andrews J, Croda J, Walter K. Phylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay. Nature Communications 2023, 14: 303. PMID: 36658111, PMCID: PMC9849832, DOI: 10.1038/s41467-023-35813-9.Peer-Reviewed Original ResearchMeSH KeywordsHumansMycobacterium tuberculosisParaguayPhylogeographyPrisonsProspective StudiesTuberculosisConceptsIncident tuberculosis casesTB control programsTuberculosis casesRecent transmissionTransmission clustersNew infectionsProspective genomic surveillanceTransmission riskM. tuberculosisMycobacterium tuberculosisGenomic surveillanceMycobacterium tuberculosis complex genomeTuberculosisOutside prisonTransmission linkageControl programsInfectionIncidenceDelay in the diagnosis and treatment of tuberculosis in prisons in Mato Grosso do Sul, Brazil
Ribeiro C, da Silva Santos A, Tshua D, de Oliveira R, Lemos E, Bourdillon P, Laranjeira A, Gonçalves C, Andrews J, Ko A, Croda J. Delay in the diagnosis and treatment of tuberculosis in prisons in Mato Grosso do Sul, Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0015-2023. PMID: 37493729, PMCID: PMC10367220, DOI: 10.1590/0037-8682-0015-2023.Peer-Reviewed Original ResearchConceptsSymptom onsetFirst symptomsLargest male prisonPrison medical recordsTB case dataRetrospective cohort studyPulmonary TB casesYear of diagnosisStart of treatmentTreatment of TBTreatment of tuberculosisNumber of symptomsAverage timePercentage of cureProvider delayTB casesCohort studyTreatment initiationHIV statusSmoking statusTuberculosis casesTB transmissionFirst consultationPatient delayMedical recordsResearch, Innovation, and National Production of Strategic Inputs for Tuberculosis Elimination in Brazil: Contributions from the REDE-TB
Arcêncio R, Chimara E, Lapa e Silva J, Croda J, Carvalho A. Research, Innovation, and National Production of Strategic Inputs for Tuberculosis Elimination in Brazil: Contributions from the REDE-TB. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0518-2023. PMID: 38055542, PMCID: PMC10691762, DOI: 10.1590/0037-8682-0518-2023.Peer-Reviewed Original Research
2022
Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis
Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, Fox G, Carvalho A, Chan P, Croda J, Hill P, Lopez-Varela E, Donkor S, Fielding K, Graham S, Espinal M, Kampmann B, Reingold A, Huerga H, Villalba J, Grandjean L, Sotgiu G, Egere U, Singh S, Zhu L, Lienhardt C, Denholm J, Seddon J, Whalen C, García-Basteiro A, Triasih R, Chen C, Singh J, Huang L, Sharma S, Hannoun D, Del Corral H, Mandalakas A, Malone L, Ling D, Kritski A, Stein C, Vashishtha R, Boulahbal F, Fang C, Boom W, Netto E, Lemos A, Hesseling A, Kay A, Jones-López E, Horsburgh C, Lange C, Andrews J. Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis. The Lancet Global Health 2022, 10: e1307-e1316. PMID: 35961354, PMCID: PMC10406427, DOI: 10.1016/s2214-109x(22)00283-2.Peer-Reviewed Original ResearchConceptsInfant BCG vaccinationBCG vaccinationExtrapulmonary tuberculosisCohort studyIndividual participant dataPulmonary tuberculosisParticipant dataSystematic reviewIndividual-level participant dataPositive tuberculin skin testMultivariable logistic regression analysisTuberculin skin testTuberculosis infection statusParticipant-level dataLogistic regression analysisAge-specific impactStudy-level random effectWeb of ScienceIncident tuberculosisPrevious tuberculosisTuberculosis developmentSecondary outcomesTuberculosis contactsPrimary outcomeSkin testThe effect of incarceration on TB treatment outcomes
O Marr J, Gonçalves C, Arakaki-Sanchez D, Pelissari D, Costa F, Croda J, Walter K, Andrews J. The effect of incarceration on TB treatment outcomes. The International Journal Of Tuberculosis And Lung Disease 2022, 26: 252-258. PMID: 35197165, DOI: 10.5588/ijtld.21.0449.Peer-Reviewed Original ResearchMeSH KeywordsDirectly Observed TherapyHumansOdds RatioPrisonersPrisonsRisk FactorsTreatment OutcomeTuberculosisConceptsNon-incarcerated individualsTreatment successTreatment outcomesDrug-susceptible TB casesImproved treatment successTB treatment outcomesTB treatment successClinical risk factorsIncarcerated individualsMultivariate logistic regressionGreater treatment successTB casesClinical factorsObserved therapyPoor outcomeTB notificationsRisk factorsElevated riskGreater efficacyLogistic regressionNotifiable diseaseOutcomesIncarcerated populationsVulnerable individualsUse of DOTTuberculosis in prison inmates in Southern Brazil: investigating the epidemiological and operational indicators
Busatto C, Mespaque J, Schwarzbold P, de Souza C, Jarczewski C, Meucci R, Andrews J, Croda J, da Silva P, Ramis I, Possuelo L. Tuberculosis in prison inmates in Southern Brazil: investigating the epidemiological and operational indicators. Revista Da Sociedade Brasileira De Medicina Tropical 2022, 55: e0052-2022. PMID: 36287468, PMCID: PMC9592108, DOI: 10.1590/0037-8682-0052-2022.Peer-Reviewed Original ResearchConceptsPulmonary tuberculosis casesTuberculosis casesPulmonary tuberculosisLaboratory confirmationNew casesNew pulmonary tuberculosis casesRetreatment pulmonary tuberculosis casesWorldwide public health problemNotifiable Diseases Information SystemNew TB casesPublic health problemPublic health measuresTB casesHIV testingTuberculosis controlLaboratory criteriaTuberculosis incidenceIncidence rateObservational studyHealth problemsHealth measuresTuberculosisSpecific populationsHIVInvestigation rates
2021
Advancing TB research using digitized programmatic data
Taaffe J, Croda J, Moultrie H, Silva D, Rosenthal A, Farhat M. Advancing TB research using digitized programmatic data. The International Journal Of Tuberculosis And Lung Disease 2021, 25: 890-895. PMID: 34686230, PMCID: PMC8544923, DOI: 10.5588/ijtld.21.0325.Peer-Reviewed Original ResearchPooling Sputum Samples for Efficient Mass Tuberculosis Screening in Prisons
Dos Santos P, da Silva Santos A, de Oliveira R, da Silva B, Soares T, Martinez L, Verma R, Andrews J, Croda J. Pooling Sputum Samples for Efficient Mass Tuberculosis Screening in Prisons. Clinical Infectious Diseases 2021, 74: 2115-2121. PMID: 34718459, PMCID: PMC9258923, DOI: 10.1093/cid/ciab847.Peer-Reviewed Original ResearchMeSH KeywordsHumansMass ScreeningMycobacterium tuberculosisPrisonsSensitivity and SpecificitySputumTuberculosisConceptsWorld Health OrganizationTuberculosis screeningMycobacterial loadHigh prevalenceSputum samplesMass screeningHigh tuberculosis prevalenceHigh-risk groupHigher mycobacterial loadPositive samplesTuberculosis casesPrevalence settingsTuberculosis prevalenceLow prevalenceSingle positive samplePrevalenceActive casesHealth Organization
2020
Increased incarceration rates drive growing tuberculosis burden in prisons and jeopardize overall tuberculosis control in Paraguay
Sequera V, Aguirre S, Estigarribia G, Cellamare M, Croda J, Andrews J, Martinez L, García-Basteiro A. Increased incarceration rates drive growing tuberculosis burden in prisons and jeopardize overall tuberculosis control in Paraguay. Scientific Reports 2020, 10: 21247. PMID: 33277515, PMCID: PMC7718226, DOI: 10.1038/s41598-020-77504-1.Peer-Reviewed Original ResearchMeSH KeywordsCommunicable DiseasesFemaleHumansMaleParaguayPrisonersPrisonsRespiratory Tract DiseasesTuberculosisConceptsTB casesPopulation attributable fractionAttributable fractionAnnual TB notification ratesNational TB Control ProgrammeOverall population attributable riskIncarcerated populationsTB control programsCharacteristics of tuberculosisPopulation attributable riskTB notification ratesTB control measuresTrend of tuberculosisPercentage of casesSame age groupIncarcerated casesTB burdenTB controlTuberculosis burdenCase RegistryTuberculosis controlTB epidemicAttributable riskNotification ratesRelative riskPrimary Prophylaxis to Prevent Tuberculosis Infection in Prison Inmates: A Randomized, Double-Blind, Placebo-Controlled Trial.
Dias de Oliveira R, da Silva Santos A, Reis C, de Cássia Leite A, Correia Sacchi F, de Araujo R, Dos Santos P, Rolla V, Martinez L, Andrews J, Croda J. Primary Prophylaxis to Prevent Tuberculosis Infection in Prison Inmates: A Randomized, Double-Blind, Placebo-Controlled Trial. American Journal Of Tropical Medicine And Hygiene 2020, 103: 1466-1472. PMID: 32876010, PMCID: PMC7543866, DOI: 10.4269/ajtmh.20-0110.Peer-Reviewed Original ResearchConceptsQFT conversionTB infectionSecondary outcomesPlacebo-controlled trialQuantiFERON-TB GoldFuture clinical trialsPrimary prophylaxisMiddle-income countriesPrimary outcomeTuberculosis infectionIntervention armTuberculosis incidenceControl armTrial protocolClinical trialsElevated riskInterim analysisLatent infectionCutoff pointInfectionTrialsHigher cutoffSustained conversionInternational unitsLower ratesGenomic variant-identification methods may alter Mycobacterium tuberculosis transmission inferences
Walter KS, Colijn C, Cohen T, Mathema B, Liu Q, Bowers J, Engelthaler DM, Narechania A, Lemmer D, Croda J, Andrews JR. Genomic variant-identification methods may alter Mycobacterium tuberculosis transmission inferences. Microbial Genomics 2020, 6: mgen000418. PMID: 32735210, PMCID: PMC7641424, DOI: 10.1099/mgen.0.000418.Peer-Reviewed Original ResearchCost-effectiveness of a Pharmacogenomic Test for Stratified Isoniazid Dosing in Treatment of Active Tuberculosis
Rens N, Groot C, Goldhaber-Fiebert J, Croda J, Andrews J. Cost-effectiveness of a Pharmacogenomic Test for Stratified Isoniazid Dosing in Treatment of Active Tuberculosis. Clinical Infectious Diseases 2020, 71: 3136-3143. PMID: 31905381, PMCID: PMC7819527, DOI: 10.1093/cid/ciz1212.Peer-Reviewed Original ResearchConceptsDrug-susceptible tuberculosisIncremental cost-effectiveness ratioSlow NAT2 acetylatorsWeight-based dosingOne-way sensitivity analysesCost-effectiveness ratioN-acetyltransferase 2 geneEffectiveness of drugsProbabilistic sensitivity analysesPotential clinical impactGeneXpert testActive tuberculosisNAT2 acetylatorsTreatment failurePharmacokinetic variabilityRapid acetylatorsTuberculosis treatmentClinical impactMAIN OUTCOMEPharmacogenomic testsHealth outcomesIsoniazid toxicityInterindividual variabilityPatientsTuberculosisA summary of the proceedings of a meeting on the treatment of latent tuberculosis infection in target populations in Brazil
Rolla V, Trajman A, Kawamura M, Cavalcante S, Soares E, Perini F, Carvalho A, Croda J, Silva J, Schmaltz C, Sant'Anna F, Bastos M, Gomes A, Durovni B, Saraceni V, Silva E, Mello F, Santos M, Pinto M. A summary of the proceedings of a meeting on the treatment of latent tuberculosis infection in target populations in Brazil. Jornal Brasileiro De Pneumologia 2020, 46: e20200023. PMID: 32696834, PMCID: PMC7567628, DOI: 10.36416/1806-3756/e20200023.Peer-Reviewed Original Research
2019
Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.
Tatara M, Perdigão J, Viveiros M, Kritski A, Silva K, Sacchi F, de Lima C, Dos Santos P, Diniz J, Almeida Silva P, Gomes P, Gomes M, Cunha E, Lapa E Silva J, Portugal I, Croda J, Andrade M. Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil. American Journal Of Tropical Medicine And Hygiene 2019, 101: 774-779. PMID: 31392954, PMCID: PMC6779181, DOI: 10.4269/ajtmh.19-0324.Peer-Reviewed Original ResearchConceptsPopulation-based prospective studyDrug resistanceMolecular epidemiologyResistance profilesRepetitive units-variable numberMTB/RIFDrug susceptibility testDrug resistance profilesTransmission of MtbPublic health policyPhenotypic resistance profilesIsoniazid monoTB preventionProspective studyNew strain typesTB epidemiologyPrimary resistanceHigh prevalenceMTB isolatesProportion methodHealth policyMycobacterium tuberculosisSusceptibility testsTuberculosisVulnerable populationsPaediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies
Martinez L, Lo N, Cords O, Hill P, Khan P, Hatherill M, Mandalakas A, Kay A, Croda J, Horsburgh C, Zar H, Andrews J. Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies. The Lancet Respiratory Medicine 2019, 7: 544-552. PMID: 31078497, PMCID: PMC7323920, DOI: 10.1016/s2213-2600(19)30137-7.Peer-Reviewed Original ResearchConceptsM tuberculosis transmissionHousehold contact tracingTuberculosis transmissionFuture public health strategiesContact tracingGlobal tuberculosis control effortsAdult tuberculosis casesPaediatric tuberculosis infectionMycobacterium tuberculosis transmissionHigh-burden settingsTuberculosis control effortsEffective public health responsePopulation attributable fractionPublic health strategiesAge 5 yearsCommunity-based interventionsPublic health interventionsPublic health responsePediatric transmissionChildhood tuberculosisTuberculosis infectionTuberculosis casesActive surveillanceHealth strategiesHousehold exposure