2021
Toxicological analysis and efficacy of 2-phenylchromone on mycobacteria viability and inflammatory response induced by Mycobacterium bovis
Moreira F, Radai J, de Souza V, Berno C, de Araújo F, Andrade-Silva M, Oliveira R, Arena A, de Oliveira Henriques M, Kassuya C, Croda J. Toxicological analysis and efficacy of 2-phenylchromone on mycobacteria viability and inflammatory response induced by Mycobacterium bovis. Phytomedicine Plus 2021, 1: 100117. DOI: 10.1016/j.phyplu.2021.100117.Peer-Reviewed Original ResearchInflammatory responseOral treatmentSplenic phagocytosisTumor necrosis factor levelsAnti-inflammatory actionNecrosis factor levelsAcute oral toxicity testAnti-inflammatory propertiesMycobacterium bovisMycobacterium tuberculosis strainsDifferential leukocyte countsOral toxicity testPleurisy inductionCytokine productionPleurisy modelLeukocyte countMinimum inhibitory concentrationMycobacteria infectionMycobacteria viabilityPleural exudatesLeukocyte migrationTuberculosis strainsVivo modelToxicity signsFactor levels
2020
Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study
de Miranda S, de Almeida I, de Fátima Filardi Oliveira Mansur M, de Assis Figueredo L, da Silva Carvalho W, Hadaad J, do Carmo Guimarães Diniz J, von Groll A, da Silva P, Lopes M, dos Santos M, Brito A, de Queiroz Mello F, da Silva Santos Malaquias T, Croda J, Pinhata J, de Oliveira R, Chimara E, Rossetti M, Halon M, Lourenço M, de Melo Medeiros R, Montes F, Machado D, Viveiros M, Kritski A. Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study. Brazilian Archives Of Biology And Technology 2020, 63: e20190179. DOI: 10.1590/1678-4324-2020190179.Peer-Reviewed Original ResearchLowenstein-Jensen mediumMulticenter studyProportion methodDrug-resistant Mycobacterium tuberculosis strainsResistant Mycobacterium tuberculosis strainsM. tuberculosis clinical isolatesJensen mediumGold standardTuberculosis clinical isolatesMycobacterium tuberculosis resistanceMycobacterium tuberculosis strainsMiddle-income countriesTreatment drugsTuberculosis strainsClinical isolatesTuberculosis resistanceSusceptibility test kitsEthambutolIncome countriesTest kitIsoniazidRifampicinPresent studyKitStreptomycin
2015
Prisons as Reservoir for Community Transmission of Tuberculosis, Brazil - Volume 21, Number 3—March 2015 - Emerging Infectious Diseases journal - CDC
Sacchi FP, Praça RM, Tatara MB, Simonsen V, Ferrazoli L, Croda MG, Suffys PN, Ko AI, Andrews JR, Croda J. Prisons as Reservoir for Community Transmission of Tuberculosis, Brazil - Volume 21, Number 3—March 2015 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2015, 21: 452-455. PMID: 25642998, PMCID: PMC4344267, DOI: 10.3201/eid2103.140896.Peer-Reviewed Original Research
2014
Evaluation of the anti-mycobacterium tuberculosis activity and in vivo acute toxicity of Annona sylvatic
Araujo R, Neves F, Formagio A, Kassuya C, Stefanello M, Souza V, Pavan F, Croda J. Evaluation of the anti-mycobacterium tuberculosis activity and in vivo acute toxicity of Annona sylvatic. BMC Complementary Medicine And Therapies 2014, 14: 209. PMID: 24974069, PMCID: PMC4082671, DOI: 10.1186/1472-6882-14-209.Peer-Reviewed Original ResearchConceptsVivo acute toxicityAnti-mycobacterial activityLC-MSFirst chemical characterizationAnti-Mycobacterium tuberculosis activityLiquid-liquid partitioningMinimal inhibitory concentrationEthyl acetate fractionChemical characterizationAntituberculosis activitySpectroscopic dataBody weightIsolation of quercetinAcute toxicityChemical fractionationChromatographic analysisFemale Swiss miceMultidrug-resistant Mycobacterium tuberculosis strainsControl of tuberculosisAcute toxicity evaluationToxicity evaluationMycobacterium tuberculosis strainsTuberculosis activityAlmunequinEAF fractions