2023
Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study
Busatto C, Possuelo L, Bierhals D, de Oliveira C, de Souza M, Fanfa D, Barreto É, Schwarzbold P, Von Groll A, Portugal I, Perdigão J, Croda J, Andrews J, da Silva P, Ramis I. Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study. European Journal Of Clinical Microbiology & Infectious Diseases 2023, 42: 297-304. PMID: 36701032, DOI: 10.1007/s10096-023-04546-4.Peer-Reviewed Original ResearchConceptsAnti-TB drug resistanceM. tuberculosisTB control programsCross-sectional studyM. tuberculosis strainsMolecular epidemiology studiesTB burdenLAM strainsTuberculosis strainsEpidemiology studiesDrug resistanceMycobacterium tuberculosisCentral laboratoryTranslational researchTuberculosisCommon strainControl programsPDLMolecular characterizationHaarlemImproved strategiesPersonsPhylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay
Sanabria G, Sequera G, Aguirre S, Méndez J, dos Santos P, Gustafson N, Godoy M, Ortiz A, Cespedes C, Martínez G, García-Basteiro A, Andrews J, Croda J, Walter K. Phylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay. Nature Communications 2023, 14: 303. PMID: 36658111, PMCID: PMC9849832, DOI: 10.1038/s41467-023-35813-9.Peer-Reviewed Original ResearchConceptsIncident tuberculosis casesTB control programsTuberculosis casesRecent transmissionTransmission clustersNew infectionsProspective genomic surveillanceTransmission riskM. tuberculosisMycobacterium tuberculosisGenomic surveillanceMycobacterium tuberculosis complex genomeTuberculosisOutside prisonTransmission linkageControl programsInfectionIncidence
2019
A fieldable electrostatic air sampler enabling tuberculosis detection in bioaerosols
de Sousa N, Sandström N, Shen L, Håkansson K, Vezozzo R, Udekwu K, Croda J, Rothfuchs A. A fieldable electrostatic air sampler enabling tuberculosis detection in bioaerosols. Tuberculosis 2019, 120: 101896. PMID: 32090857, PMCID: PMC7049907, DOI: 10.1016/j.tube.2019.101896.Peer-Reviewed Original ResearchConceptsTB hotspotsM. tuberculosisActive pulmonary diseaseAirborne M. tuberculosisElectrostatic air samplerInhalation of aerosolsViable Mycobacterium tuberculosisPulmonary diseaseTB controlTB transmissionM. bovis BCGTuberculosisInfectious diseasesMycobacterium tuberculosisBovis BCGTuberculosis detectionMore human livesMolecular signaturesDiseaseCoughPatientsWorld populationInhalationBCGImportant role
2016
Synthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives
Moreira F, Croda J, Sarragiotto M, Foglio M, Ruiz A, Carvalho J, Formagio A. Synthesis, in vitro Antiproliferative and Anti-Mycobacterium tuberculosis Activities of Novel β-Carboline Derivatives. Journal Of The Brazilian Chemical Society 2016, 27: 1398-1405. DOI: 10.5935/0103-5053.20160062.Peer-Reviewed Original ResearchM. tuberculosisNCI/ADRNCI/ADR cellsCell linesAnti-Mycobacterium tuberculosis activityCancer cell linesHuman cancer cell linesAnti-Mycobacterium tuberculosisΒ-carbolinesTumor cell linesGrowth inhibitory activityADR cellsTuberculosis activityOral bioavailabilityHuman tumor cell linesTerminal guanidine groupTuberculosisΒ-carboline derivativesInhibitory activityAntiproliferative activitySignificant activityGreater activityNovel β-carboline derivativesSilico studiesGroup