Tracing the evolution of single-cell 3D genomes in Kras-driven cancers
Liu M, Jin S, Agabiti S, Jensen T, Yang T, Radda J, Ruiz C, Baldissera G, Rajaei M, Li F, Townsend J, Muzumdar M, Wang S. Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. Nature Genetics 2025, 1-13. PMID: 40825871, DOI: 10.1038/s41588-025-02297-w.Peer-Reviewed Original ResearchCell-to-cell heterogeneityGenome-wide chromatinGenome compactionGenome architectureGenomic structureGenome mappingGenome regulationLung adenocarcinomaDependent genesKRAS-driven cancersGenomeMouse lung adenocarcinomaCancer progressionEarly tumor progressionSingle cellsCancer stateGenesPancreatic ductal adenocarcinomaInvasive tumorsTherapeutic biomarkersDuctal adenocarcinomaTumor progressionCompartmental changesChromatinCancer
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply