2021
Analyzing gut microbiota composition in individual Anopheles mosquitoes after experimental treatment
Fofana A, Gendrin M, Romoli O, Yarbanga G, Ouédraogo G, Yerbanga R, Ouédraogo J. Analyzing gut microbiota composition in individual Anopheles mosquitoes after experimental treatment. IScience 2021, 24: 103416. PMID: 34901787, PMCID: PMC8637483, DOI: 10.1016/j.isci.2021.103416.Peer-Reviewed Original ResearchMosquito microbiotaHigh-throughput sequencing studiesHigh-throughput sequencingMosquito microbiomeMicrobiota compositionBlood digestionSemi-field conditionsMajor generaSequencing studiesGut samplesReduced microbial loadRelative abundanceMalaria transmissionOverall microbiota compositionBlood mealGut microbiota compositionInfluence of amoxicillinAnopheles mosquitoesAdult femalesNegative control dataMicrobiotaAntibiotic treatmentSpecific decreaseAmoxicillin preparationsMicrobial load
2016
Differential Effects of Azithromycin, Doxycycline, and Cotrimoxazole in Ingested Blood on the Vectorial Capacity of Malaria Mosquitoes
Gendrin M, Yerbanga R, Ouedraogo J, Lefèvre T, Cohuet A, Christophides G. Differential Effects of Azithromycin, Doxycycline, and Cotrimoxazole in Ingested Blood on the Vectorial Capacity of Malaria Mosquitoes. Open Forum Infectious Diseases 2016, 3: ofw074. PMID: 27419152, PMCID: PMC4943539, DOI: 10.1093/ofid/ofw074.Peer-Reviewed Original ResearchIngested bloodMass drug administration programsMosquito lifespanEffect of doxycyclineDrug administration programsMosquito vectorial capacityAntibiotic treatmentMosquito microbiotaPlasmodium infectionBlood meal supplementationInfection loadVectorial capacityGut microbiotaMalaria transmissionAzithromycinMalaria parasitesPlasmodium falciparumDisease eliminationDoxycyclineMalaria vector mosquitoesAntibioticsBlood mealDifferential effectsInfection intensityMicrobiota
2015
Antibiotics in ingested human blood affect the mosquito microbiota and capacity to transmit malaria
Gendrin M, Rodgers F, Yerbanga R, Ouédraogo J, Basáñez M, Cohuet A, Christophides G. Antibiotics in ingested human blood affect the mosquito microbiota and capacity to transmit malaria. Nature Communications 2015, 6: 5921. PMID: 25562286, PMCID: PMC4338536, DOI: 10.1038/ncomms6921.Peer-Reviewed Original ResearchConceptsMass drug administration programsHigh antibiotic usageDrug administration programsBlood of childrenAnopheles gambiae mosquitoesMalaria infectionAntibiotic exposureMosquito bitesHigh riskAntibiotic usageMalaria reductionGut microbiotaMalaria transmissionCommunicable diseasesPlasmodium falciparumBloodIngested bloodGambiae mosquitoesAntibioticsHuman bloodDisease transmissionDiseaseMosquito survivalMosquito microbiotaVectorial capacity