2018
In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice
Bonkian L, Yerbanga R, Koama B, Soma A, Cisse M, Valea I, Tinto H, Ouedraogo J, Guigemde T, Traore/Coulibaly M. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evidence-based Complementary And Alternative Medicine 2018, 2018: 6859632. PMID: 29977316, PMCID: PMC5994278, DOI: 10.1155/2018/6859632.Peer-Reviewed Original ResearchArtemisinin-based combination therapyWorld Health OrganizationNMRI miceBody weightUncomplicated malaria treatmentAntiplasmodial activityVivo antiplasmodial activityPercentage of reductionFour-day treatmentControl of malariaExtract/Thin blood smearsCombination therapyMalaria treatmentPrimary treatmentControl groupDay fiveBlood smearsCandidate drugsHerbal medicineHealth OrganizationMalariaLeaf decoctionTreatmentParasitaemia
2015
Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds
Abay S, Lucantoni L, Dahiya N, Dori G, Dembo E, Esposito F, Lupidi G, Ogboi S, Ouédraogo R, Sinisi A, Taglialatela-Scafati O, Yerbanga R, Bramucci M, Quassinti L, Ouédraogo J, Christophides G, Habluetzel A. Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds. Malaria Journal 2015, 14: 288. PMID: 26208861, PMCID: PMC4513948, DOI: 10.1186/s12936-015-0812-2.Peer-Reviewed Original ResearchConceptsEarly sporogonic stagesOocyst prevalenceVivo transmissionHuman parasite P. falciparumP. berghei parasitesMalaria control toolsAnopheles stephensi mosquitoesEthanolic leaf extractVernonia amygdalina extractPreventive treatmentBerghei parasitesField isolatesAnopheles coluzzii mosquitoesParasite P. falciparumP. falciparumBackgroundMedicinal plantsStephensi mosquitoesPlasmodium transmissionHerbal medicineMurine parasitePlasmodium falciparumLeaf extractPrevalenceCytotoxic effectsSporogonic stages