2022
Small-quantity lipid-based nutrient supplements, with or without added zinc, do not cause excessive fat deposition in Burkinabe children: results from a cluster-randomized community trial
Abbeddou S, Jimenez E, Hess S, Somé J, Ouédraogo J, Brown K. Small-quantity lipid-based nutrient supplements, with or without added zinc, do not cause excessive fat deposition in Burkinabe children: results from a cluster-randomized community trial. European Journal Of Nutrition 2022, 61: 4107-4120. PMID: 35829783, PMCID: PMC9596589, DOI: 10.1007/s00394-022-02936-6.Peer-Reviewed Original ResearchConceptsSmall-quantity lipid-based nutrient supplementsNon-intervention cohortLipid-based nutrient supplementsIntervention cohortIntervention groupCluster-randomized community trialFat-free mass accretionAdditional zinc supplementationFat depositionTrial registrationThe studyCluster-randomized trial designDispersible tabletsMonths of ageExcessive fat depositionMorbidity treatmentNIC childrenNutrient supplementsBurkinabe childrenUS National InstitutesObesity riskZinc supplementationClinical trialsCommunity trialFat massTrial design
2017
Additional Zinc Delivered as a Tablet and SQ‐LNS May Increase Fat Free Mass Accrual in Young Burkinabe Children
Jimenez E, Abbeddou S, Coulibaly N, Some J, Ouedraogo J, Brown K, Hess S. Additional Zinc Delivered as a Tablet and SQ‐LNS May Increase Fat Free Mass Accrual in Young Burkinabe Children. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.316.2.Peer-Reviewed Original ResearchNon-intervention cohortFat-free massSQ-LNSIntervention cohortDose groupMonths of ageBody compositionBurkinabe childrenNIC groupZinc tabletsSmall-quantity lipid-based nutrient supplementsBaseline fat-free massFree massLipid-based nutrient supplementsWeight gainYoung Burkinabe childrenChildren's body compositionCollection of salivaSubgroup of childrenTwo-stage clusterNIC childrenOverall weight gainFat massIC groupSupplemental zincSmall-quantity lipid-based nutrient supplements containing different amounts of zinc along with diarrhea and malaria treatment increase iron and vitamin A status and reduce anemia prevalence, but do not affect zinc status in young Burkinabe children: a cluster-randomized trial
Abbeddou S, Yakes Jimenez E, Somé J, Ouédraogo J, Brown. K, Hess S. Small-quantity lipid-based nutrient supplements containing different amounts of zinc along with diarrhea and malaria treatment increase iron and vitamin A status and reduce anemia prevalence, but do not affect zinc status in young Burkinabe children: a cluster-randomized trial. BMC Pediatrics 2017, 17: 46. PMID: 28152989, PMCID: PMC5288861, DOI: 10.1186/s12887-016-0765-9.Peer-Reviewed Original ResearchConceptsSmall-quantity lipid-based nutrient supplementsNon-intervention cohortLipid-based nutrient supplementsRetinol-binding proteinIntervention cohortAnemia prevalenceIllness treatmentIC childrenYoung Burkinabe childrenLower retinol-binding proteinSoluble transferrin receptorLower anemia prevalenceIron deficiency prevalenceCluster-randomized trialIndicators of ironPackage of interventionsIndicator of vitaminMonths of ageDifferent treatment groupsGroup-wise differencesTwo-stage clusterNIC childrenNutrient supplementsResultsAt baselineBurkinabe children
2016
Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial 1–3
Becquey E, Ouédraogo C, Hess S, Rouamba N, Prince L, Ouédraogo J, Vosti S, Brown K. Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial 1–3. Journal Of Nutrition 2016, 146: 2058-2066. PMID: 27489011, DOI: 10.3945/jn.116.230128.Peer-Reviewed Original ResearchConceptsTherapeutic zinc supplementationPreventive zinc supplementationZinc supplementationNonintervention controlsMalaria incidenceDiarrhea incidenceZinc-deficient populationsPrevalence of diarrheaPlasma zinc concentrationTreatment of diarrheaPrimary outcomeBurkinabe childrenMSC groupLower incidenceNIC groupStudy groupTreatment groupsPrimary analysisControl groupDiarrheaIncidenceSupplementationTrial 1Young childrenFever
2015
Iodine status of young Burkinabe children receiving small-quantity lipid-based nutrient supplements and iodised salt: a cluster-randomised trial
Hess S, Abbeddou S, Jimenez E, Ouédraogo J, Brown K. Iodine status of young Burkinabe children receiving small-quantity lipid-based nutrient supplements and iodised salt: a cluster-randomised trial. British Journal Of Nutrition 2015, 114: 1829-1837. PMID: 26411504, DOI: 10.1017/s0007114515003554.Peer-Reviewed Original ResearchConceptsSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsThyroid-stimulating hormoneNon-intervention cohortMonths of ageYoung Burkinabe childrenUrinary iodineNIC childrenBurkinabe childrenIodised saltNational salt iodization programSpot urinary iodineCluster-randomised trialSalt iodization programNutrient supplementsSalt iodisation programmeIodine statusLow T4Thyroglobulin concentrationIodization programTotal thyroxineBlood spotsI statusIC childrenCohortAnemia And Iron Supplementation Is Not Associated with Malaria in Young Burkinabe Children
Some J, Abbeddou S, Jimenez E, Ouedraogo Z, Ouedraogo J, Brown K, Hess S. Anemia And Iron Supplementation Is Not Associated with Malaria in Young Burkinabe Children. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.757.9.Peer-Reviewed Original ResearchLipid-based nutrient supplementsRapid diagnostic testsYoung Burkinabe childrenBurkinabe childrenIron supplementationFe supplementsPositive malaria rapid diagnostic testPositive rapid diagnostic testMalaria rapid diagnostic testsRandomized clinical trialsIncidence of malariaMo of ageMalaria episodesAntimalarial treatmentSevere anemiaModerate anemiaClinical trialsAnthelminthic treatmentHome visitsMalaria diagnosisHemoglobin concentrationMalaria incidenceIron treatmentDiagnostic testsMalariaTreated Malaria Does Not Affect Physical Growth And Hemoglobin Concentration of Young Children in Burkina Faso
Some J, Abbeddou S, Jimenez E, Hess S, Ouedraogo Z, Guissou R, Vosti S, Ouedraogo J, Brown K. Treated Malaria Does Not Affect Physical Growth And Hemoglobin Concentration of Young Children in Burkina Faso. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.757.7.Peer-Reviewed Original ResearchLipid-based nutrient supplementationRapid diagnostic testsPhysical growthHemoglobin concentrationZ-scoreYoung Burkinabe childrenLength z-scoreCause of anemiaAssociation of malariaAge z-scoreYoung childrenMo of ageMalaria episodesMorbidity assessmentBurkinabe childrenMean changeMalariaDiagnostic testsDifferent dosesEarly childhoodChildrenDiarrheaFeverEpisodesFrequency categoriesSmall-Quantity Lipid-Based Nutrient Supplements, Regardless of Their Zinc Content, Increase Growth and Reduce the Prevalence of Stunting and Wasting in Young Burkinabe Children: A Cluster-Randomized Trial
Hess S, Abbeddou S, Jimenez E, Somé J, Vosti S, Ouédraogo Z, Guissou R, Ouédraogo J, Brown K. Small-Quantity Lipid-Based Nutrient Supplements, Regardless of Their Zinc Content, Increase Growth and Reduce the Prevalence of Stunting and Wasting in Young Burkinabe Children: A Cluster-Randomized Trial. PLOS ONE 2015, 10: e0122242. PMID: 25816354, PMCID: PMC4376671, DOI: 10.1371/journal.pone.0122242.Peer-Reviewed Original ResearchConceptsSmall-quantity lipid-based nutrient supplementsNon-intervention cohortPlacebo tabletsLipid-based nutrient supplementsYoung Burkinabe childrenOral rehydration saltsPrevalence of stuntingIncidence of diarrheaCluster-randomized trialPlasma zinc concentrationMonths of ageBaseline hemoglobinMorbidity surveillanceNutrient supplementsStandard careDiarrhea treatmentRehydration saltsAnemia prevalenceBurkinabe childrenIllness surveillanceAntimalarial therapyIntervention groupIllness treatmentZinc tabletsZinc levelsZinc added in Different Amounts to Small-quantity Lipid-based Nutrient Supplements (SQ-LNS) or provided as a Tablet did not affect Diarrhea or Malaria Morbidity in young, Rural Burkinabe Children
Somé J, Abbeddou S, Jimenez E, Ouédraogo Z, Guissou R, Peerson J, Hess S, Vosti S, Ouédraogo J, Brown K. Zinc added in Different Amounts to Small-quantity Lipid-based Nutrient Supplements (SQ-LNS) or provided as a Tablet did not affect Diarrhea or Malaria Morbidity in young, Rural Burkinabe Children. European Journal Of Nutrition & Food Safety 2015, 5: 443-444. DOI: 10.9734/ejnfs/2015/20902.Peer-Reviewed Original ResearchIodine Status of Young Burkinabe Children Receiving Small-quantity Lipid-based Nutrient Supplements and Iodized Salt
Hess S, Abbeddou S, Jimenez E, Ouedraogo J, Brown K. Iodine Status of Young Burkinabe Children Receiving Small-quantity Lipid-based Nutrient Supplements and Iodized Salt. European Journal Of Nutrition & Food Safety 2015, 5: 713-714. DOI: 10.9734/ejnfs/2015/21045.Peer-Reviewed Original ResearchSmall-quantity Lipid-based Nutrient Supplements, Together with Malaria and Diarrhea Treatment, Improve Growth and Development in Young Burkinabe Children
Hess S, Abbeddou S, Jimenez E, Some J, Prado E, Ouédraogo Z, Guissou R, Vosti S, Ouédraogo J, Brown K. Small-quantity Lipid-based Nutrient Supplements, Together with Malaria and Diarrhea Treatment, Improve Growth and Development in Young Burkinabe Children. European Journal Of Nutrition & Food Safety 2015, 5: 715-716. DOI: 10.9734/ejnfs/2015/21046.Peer-Reviewed Original ResearchComparison of Methods to Assess Adherence to Small-quantity Lipid Based Nutrient Supplements (SQ-LNS) and Dispersible Tablets among Young Burkinabe Children Participating in a Community-based Intervention Trial
Abbeddou S, Hess S, Jimenez E, Somé J, Guissou R, Ouedraogo Z, Vosti S, Ouedraogo J, Brown K. Comparison of Methods to Assess Adherence to Small-quantity Lipid Based Nutrient Supplements (SQ-LNS) and Dispersible Tablets among Young Burkinabe Children Participating in a Community-based Intervention Trial. European Journal Of Nutrition & Food Safety 2015, 5: 1003-1004. DOI: 10.9734/ejnfs/2015/21209.Peer-Reviewed Original Research
2014
Burkinabe infants given small quantity lipid‐based nutrient supplements and illness treatment in infancy score higher in motor, language, and personal‐social development (251.1)
Prado E, Abbeddou S, Jimenez E, Somé J, Ouédraogo Z, Vosti S, Dewey K, Hess S, Ouédraogo J, Brown K. Burkinabe infants given small quantity lipid‐based nutrient supplements and illness treatment in infancy score higher in motor, language, and personal‐social development (251.1). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.251.1.Peer-Reviewed Original ResearchSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsPersonal-social developmentNon-intervention communitiesYoung Burkinabe childrenTreatment of malariaMonths of ageRural Burkina FasoNutrient supplementsSQ-LNSBurkinabe childrenIllness treatmentBrain growthAdequate nutritionMacronutrient metabolismBrain developmentIC childrenMelinda Gates FoundationDevelopment of motorChildrenMalariaLowest decileTreatmentGrant funding sourcesSDAdherence to small‐quantity lipid based nutrient supplement among young Burkinabe children (624.19)
Abbeddou S, Hess S, Jimenez E, Somé J, Guissou R, Ouedraogo Z, Vosti S, Ouedraogo J, Brown K. Adherence to small‐quantity lipid based nutrient supplement among young Burkinabe children (624.19). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.624.19.Peer-Reviewed Original ResearchSQ-LNSDays/weekHome visitsSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsSmall-Quantity LipidYoung Burkinabe childrenRandomized clinical trialsReporting of adherenceWeekly home visitsDisappearance rateWeekly adherenceNutrient supplementsBurkinabe childrenClinical trialsSupplementation regimensCaregiver interviewsFull doseHome ObservationMelinda Gates FoundationOlder childrenObservation periodAdherenceChildrenGrant funding sources
2013
Comparison of zinc protoporphyrin concentration in capillary whole blood and venous washed red blood cells among young Burkinabe children
Hess S, Yakes E, Abbeddou S, Peerson J, Some J, Ouedraogo Z, Ouedraogo J, Brown K. Comparison of zinc protoporphyrin concentration in capillary whole blood and venous washed red blood cells among young Burkinabe children. The FASEB Journal 2013, 27: 107.4-107.4. DOI: 10.1096/fasebj.27.1_supplement.107.4.Peer-Reviewed Original ResearchYoung Burkinabe childrenRed blood cellsZinc protoporphyrinPresence of malariaBurkinabe childrenBlood samplesBlood cellsWhole bloodC-reactive proteinPresence of inflammationCapillary whole blood samplesMalaria-endemic regionsZinc protoporphyrin concentrationsRapid diagnostic testsCapillary whole bloodWashed red blood cellsWhole blood samplesVenous samplesVenous bloodIron statusEndemic regionsProtoporphyrin concentrationDiagnostic testsInflammationMalaria