Somatic gene mutations involved in DNA damage response/Fanconi anemia signaling are tissue- and cell-type specific in human solid tumors
Kumar S, Du W, Zhang J, Yu H, Deng Y, Fei P. Somatic gene mutations involved in DNA damage response/Fanconi anemia signaling are tissue- and cell-type specific in human solid tumors. Frontiers In Medicine 2024, 11: 1462810. PMID: 39421870, PMCID: PMC11483370, DOI: 10.3389/fmed.2024.1462810.Peer-Reviewed Original ResearchDNA damage responsePotential driver mutationsFanconi anemiaCellular defense networkHuman cancersStudy of DNA damage responseAlteration frequencyDriver mutationsFA proteinsPan-cancer samplesSignal transductionSomatic gene mutationsDamage responseFA signalingUBE2TMutated genesCellular insultsDevelopment of effective therapeutic strategiesCell-typeMutational signaturesGene alteration patternsGenesMutationsDefense networkProstate cancer
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