2025
S‐GMAS: Genome‐Wide Mediation Analysis With Brain Subcortical Shape Mediators
Ding S, Liu R, Srivastava A, Nowakowski R, Shen L, Thompson P, Zhang H, Huang C. S‐GMAS: Genome‐Wide Mediation Analysis With Brain Subcortical Shape Mediators. Human Brain Mapping 2025, 46: e70297. PMID: 40741986, PMCID: PMC12311987, DOI: 10.1002/hbm.70297.Peer-Reviewed Original ResearchConceptsSingle-nucleotide polymorphismsMediation analysisGenetic exposuresPotential genetic variantsMediation analysis frameworkBrain imaging phenotypesSignificant mediation effectGenetic variantsGenetic effectsSubcortical shapeAlzheimer's Disease Neuroimaging InitiativeMediation effectSquare-root velocity function representationBrainIndirect effectsNeurological pathwaysClinical outcomesPathwayImaging phenotypesHilbert spaceHilbert subspaceStatistical inferenceMediators
2016
A method for integrating neuroimaging into genetic models of learning performance
Mehta CM, Gruen JR, Zhang H. A method for integrating neuroimaging into genetic models of learning performance. Genetic Epidemiology 2016, 41: 4-17. PMID: 27859682, PMCID: PMC5154929, DOI: 10.1002/gepi.22025.Peer-Reviewed Original Research
2012
Multiscale Adaptive Marginal Analysis of Longitudinal Neuroimaging Data with Time-Varying Covariates
Skup M, Zhu H, Zhang H. Multiscale Adaptive Marginal Analysis of Longitudinal Neuroimaging Data with Time-Varying Covariates. Biometrics 2012, 68: 1083-1092. PMID: 22551084, PMCID: PMC3767131, DOI: 10.1111/j.1541-0420.2012.01767.x.Peer-Reviewed Original Research
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