2025
A Relook at the Relevance of Thyroid Stimulating Hormone and Thyroid Autoimmunity for Pregnancy Outcomes: Analyses of Randomized Control Trials Data From Pregnancy and Polycystic Ovary Syndrome and Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation
Kuokkanen S, Seungdamrong A, Santoro N, Lieman H, Sun F, Wild R, Zhang H, Pal L. A Relook at the Relevance of Thyroid Stimulating Hormone and Thyroid Autoimmunity for Pregnancy Outcomes: Analyses of Randomized Control Trials Data From Pregnancy and Polycystic Ovary Syndrome and Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation. Obstetrical & Gynecological Survey 2025, 80: 561-562. DOI: 10.1097/ogx.0000000000001445.Peer-Reviewed Original ResearchPreterm deliveryThyroid autoimmunityAssessment of Multiple Intrauterine GestationsAssociated with pregnancy complicationsLow birth weightThyroid-stimulating hormonePolycystic ovary syndromeIntrauterine gestationPregnancy complicationsPregnancy outcomesOvarian stimulationBirth weightStimulating hormonePregnancy lossPregnancyAssociated with negative outcomesPretermHypothyroidismAutoimmunityThyroidTrial dataOutcomesDeliveryGestationComplications
2022
Effect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial
Barnhart K, Hansen K, Stephenson M, Usadi R, Steiner A, Cedars M, Jungheim E, Hoeger K, Krawetz S, Mills B, Alston M, Coutifaris C, Senapati S, Sonalkar S, Diamond M, Wild R, Rosen M, Sammel M, Santoro N, Eisenberg E, Huang H, Zhang H. Effect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial. Obstetrical & Gynecological Survey 2022, 77: 24-26. DOI: 10.1097/01.ogx.0000805156.32421.70.Peer-Reviewed Original Research
2021
COST-EFFECTIVENESS ANALYSIS OF THE ACTIVE TREATMENT OR NO TREATMENT (ACT OR NOT) RANDOMIZED CONTROLLED TRIAL OF THE OPTIMAL MANAGEMENT OF PERSISTENT PREGNANCIES OF UNKNOWN LOCATION
Walter J, Barnhart K, Koelper N, Santoro N, Zhang H, Thomas T, Huang H, Harvie H. COST-EFFECTIVENESS ANALYSIS OF THE ACTIVE TREATMENT OR NO TREATMENT (ACT OR NOT) RANDOMIZED CONTROLLED TRIAL OF THE OPTIMAL MANAGEMENT OF PERSISTENT PREGNANCIES OF UNKNOWN LOCATION. Fertility And Sterility 2021, 116: e77-e78. DOI: 10.1016/j.fertnstert.2021.07.216.Peer-Reviewed Original Research
2015
Utility of sonohysterography for tubal patency assessment in the pregnancy in polycystic ovary syndrome II trial
Christianson M, Legro R, Jin S, Eisenberg E, Diamond M, Hansen K, Vitek W, Styer A, Casson P, Coutifaris C, Christman G, Alvero R, Puscheck E, Christy A, Zhang H, Polotsky A, Santoro N. Utility of sonohysterography for tubal patency assessment in the pregnancy in polycystic ovary syndrome II trial. Fertility And Sterility 2015, 104: e98-e99. DOI: 10.1016/j.fertnstert.2015.07.304.Peer-Reviewed Original Research
2012
Altering Hirsutism Through Ovulation Induction in Women With Polycystic Ovary Syndrome
Roth LW, Huang H, Legro RS, Diamond MP, Coutifaris C, Carson SA, Steinkampf MP, Carr BR, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Myers ER, Zhang H, Schlaff WD. Altering Hirsutism Through Ovulation Induction in Women With Polycystic Ovary Syndrome. Obstetrics And Gynecology 2012, 119: 1151-1156. PMID: 22617579, PMCID: PMC3360417, DOI: 10.1097/aog.0b013e31825618fb.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeFerriman-Gallwey scoreClomiphene citrateOvary syndromePolycystic Ovary Syndrome IDouble-blind trialDuration of treatmentAbsence of ovulationHirsutism scoreOvulation inductionHirsute womenHirsutismSecondary analysisMetforminWomenGroup assignmentSignificant decreaseSignificant differencesTreatmentSyndromeInfertilityGreater improvementScoresPregnancyGroupPredictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility
Huang H, Hansen KR, Factor-Litvak P, Carson SA, Guzick DS, Santoro N, Diamond MP, Eisenberg E, Zhang H, Network I. Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility. Fertility And Sterility 2012, 97: 959-967.e5. PMID: 22270557, PMCID: PMC3319287, DOI: 10.1016/j.fertnstert.2012.01.090.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAlcohol DrinkingAlcoholic BeveragesChi-Square DistributionCoffeeFemaleHumansInfertilityInfertility, MaleInsemination, ArtificialLife StyleLive BirthLogistic ModelsMaleMiddle AgedMultivariate AnalysisOvulation InductionPregnancyPregnancy RateProspective StudiesRisk AssessmentRisk FactorsRisk Reduction BehaviorSuperovulationSurveys and QuestionnairesTeaTreatment OutcomeUnited StatesYoung AdultConceptsLive birth rateMale factor infertilityLive birthsPregnancy outcomesHigher pregnancyBirth ratePredictors of pregnancyAlcoholic beveragesFemale partnersOccurrence of pregnancyAcademic medical centerLifestyle factorsIntrauterine inseminationRisk factorsLifestyle questionnaireOccupational exposureMedical CenterLifestyle changesMAIN OUTCOMETreatment groupsPregnancySecondary analysisPast usersCurrent usersBirth
2011
Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies
Schlaff WD, Zhang H, Diamond MP, Coutifaris C, Casson PR, Brzyski RG, Christman GM, Barnhart KT, Trussell JC, Krawetz SA, Snyder PJ, Ohl D, Santoro N, Eisenberg E, Huang H, Legro RS, Network R. Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies. Fertility And Sterility 2011, 96: 15-18. PMID: 21645894, PMCID: PMC3151556, DOI: 10.1016/j.fertnstert.2011.05.069.Peer-Reviewed Original ResearchConceptsPolycystic Ovary Syndrome IReproductive Medicine NetworkMulticenter clinical trialMulticenter trialClinical trialsSubstantial burdenInstitutional reviewClinical investigatorsMedicine NetworkSignificant increaseBurdenTrialsInstitutional review board requirementsObjective dataIRB submissionPregnancyInfertilityHuman research participantsYearsSignificant variability
2010
Impact of the institutional research review process on initiating a clinical study: the reproductive medicine network (RMN) experience with pregnancy in polycystic ovary syndrome I and II
Schlaff W, Legro R, Diamond M, Coutifaris C, Zhang H, Network R. Impact of the institutional research review process on initiating a clinical study: the reproductive medicine network (RMN) experience with pregnancy in polycystic ovary syndrome I and II. Fertility And Sterility 2010, 94: s196-s197. DOI: 10.1016/j.fertnstert.2010.07.763.Peer-Reviewed Original Research
1996
Tree-based, Two-stage Risk Factor Analysis for Spontaneous Abortion
Zhang H, Bracken M. Tree-based, Two-stage Risk Factor Analysis for Spontaneous Abortion. American Journal Of Epidemiology 1996, 144: 989-996. PMID: 8916510, DOI: 10.1093/oxfordjournals.aje.a008869.Peer-Reviewed Original ResearchConceptsSpontaneous abortionPutative risk factorsRisk factorsPotential confoundersFirst monthYears of smokingNegative pregnancy outcomesNumber of pregnanciesRisk factor analysisNew risk factorsPotential confounding factorsPregnancy outcomesGynecologic problemsMaternal ageMore cupsMother's heightPregnancyConfounding factorsPassive exposureCocaine useLogistic regressionMantel-HaenszelAbortionConfoundersBirth control
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