2025
Identifying Genetic Variants for Brain Connectivity Using Ball Covariance Ranking and Aggregation
Dai W, Zhang H. Identifying Genetic Variants for Brain Connectivity Using Ball Covariance Ranking and Aggregation. Journal Of The American Statistical Association 2025, ahead-of-print: 1-19. DOI: 10.1080/01621459.2025.2450837.Peer-Reviewed Original ResearchSingle nucleotide polymorphismsDetect single nucleotide polymorphismsGene-based analysisControlling false discovery rateControlling false discoveriesSNP setsFunctional connectivityFalse discovery rateGenetic architectureNovel genesGenetic basisNucleotide polymorphismsGenetic variantsUK Biobank dataPsychiatric disordersDiscovery rateBrain functionFalse discoveriesBiobank dataCorrelations of neural activityBrain regionsBiological etiologyBrain connectivityEQTLNeural activity
2019
Common genetic variants have associations with human cortical brain regions and risk of schizophrenia
Bi X, Feng L, Wang S, Lin Z, Li T, Zhao B, Zhu H, Zhang H. Common genetic variants have associations with human cortical brain regions and risk of schizophrenia. Genetic Epidemiology 2019, 43: 548-558. PMID: 30941828, PMCID: PMC6559856, DOI: 10.1002/gepi.22203.Peer-Reviewed Original ResearchConceptsCortical regionsCortical brain regionsRisk of schizophreniaPrefrontal cortical regionsSymptom durationProdromal symptomsMental disordersSignificant associationBrain regionsCommon genetic variantsPhiladelphia Neurodevelopmental CohortPediatric imagingSchizophreniaNeurodevelopmental CohortCommon variantsHuman brainGenetic variantsHeritable mental disorderMagnetic resonanceAssociationWide association studyAssociation studiesGenetic effectsCohortSymptoms
2005
Localizing Value of Ictal–Interictal SPECT Analyzed by SPM (ISAS)
McNally KA, Paige AL, Varghese G, Zhang H, Novotny EJ, Spencer SS, Zubal IG, Blumenfeld H. Localizing Value of Ictal–Interictal SPECT Analyzed by SPM (ISAS). Epilepsia 2005, 46: 1450-1464. PMID: 16146441, DOI: 10.1111/j.1528-1167.2005.06705.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingElectroencephalographyEpilepsyEpilepsy, Temporal LobeFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMaleMiddle AgedNeocortexPreoperative CareReproducibility of ResultsROC CurveTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonVideotape RecordingConceptsStatistical parametric mappingIctal-interictal SPECTSeizure onsetMultiple brain regionsPostictal SPECTBrain regionsLateralized seizure onsetInterictal scansPostictal scansIctal SPECTDecreased perfusionSeizure endEpilepsy casesMesial temporalPerfusion increaseSPECT analysisSPECT scansSeizuresLocalized epilepsyParametric mappingTracer injectionSPECTInjectionPatientsEpilepsy
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