Safety and effectiveness of statins in hospitalized patients with COVID-19: Systematic review and collaborative meta-analysis of randomized controlled trials
Ortega-Paz L, Talasaz A, Sadeghipour P, Rashedi S, Connors J, Angiolillo D, Cavallari L, Jimenez D, Bastidas G, Lorenzi E, Berry L, Hills T, McAuley D, Shah T, Lansky A, Deepti S, Gaitán-Duarte H, Potpara T, Galli M, Dixon D, Piazza G, Lip G, Mehran R, Libby P, Krumholz H, Bikdeli B. Safety and effectiveness of statins in hospitalized patients with COVID-19: Systematic review and collaborative meta-analysis of randomized controlled trials. Thrombosis Research 2025, 255: 109484. PMID: 40992230, DOI: 10.1016/j.thromres.2025.109484.Peer-Reviewed Original ResearchRandomized Controlled TrialsStatin therapyCollaborative meta-analysisHospitalized patientsClinical impactImpact of statin therapyMeta-analysis of randomized controlled trialsCo-treatmentLiver enzyme abnormalitiesExcellent safety profileEffects of statinsCOVID-19 patientsNo significant differenceSafety profileEnzyme abnormalitiesLiver enzymesStatinsSafety outcomesTherapyPatientsCOVID-19 outcomesDisease severitySignificant differenceRandomized participantsSystematic review
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