Pre-implementation findings on the barriers and potential solutions to initiate same-day antiretroviral therapy among people who inject drugs in Malaysia
Oliveros D, Jenarun G, Salleh N, Saifi R, Earnshaw V, Madden L, Bromberg D, Sutherland R, Nikitin B, Kamarulzaman A, Altice F. Pre-implementation findings on the barriers and potential solutions to initiate same-day antiretroviral therapy among people who inject drugs in Malaysia. International Journal Of Drug Policy 2025, 145: 104967. PMID: 40865440, DOI: 10.1016/j.drugpo.2025.104967.Peer-Reviewed Original ResearchCommunity health workersNominal group techniqueHIV specialistsPre-implementationHighest-ranked barrierSame-day ARTSame-day antiretroviral therapyHIV treatment servicesPre-implementation findingsFear of policeInjected drugsAntiretroviral therapyHIV servicesInterpersonal stigmaHealth workersHIV providersMixed-method research strategyPre-implementation activitiesSocioecological modelImplementation barriersFocus groupsHarm reductionTreatment servicesGreater Kuala LumpurNGO partnershipsA Dyad-Based Intervention to Improve Adherence to Antiretroviral Therapy among People with HIV who Inject Drugs in Kazakhstan: Results of a Randomized Controlled Trial
Davis A, Rozental E, Bolger N, Gulyayev V, Gulyayev P, Denebayeva A, Wen H, Cui J, Terlikbayeva A, Primbetova S, Samandas J, Altice F, Remien R, Mergenova G. A Dyad-Based Intervention to Improve Adherence to Antiretroviral Therapy among People with HIV who Inject Drugs in Kazakhstan: Results of a Randomized Controlled Trial. AIDS And Behavior 2025, 1-13. PMID: 40773102, DOI: 10.1007/s10461-025-04841-5.Peer-Reviewed Original ResearchAntiretroviral therapy adherencePost-interventionIntervention armSelf-reported ART adherenceAntiretroviral therapySocial support interventionsImmediately post-interventionLargest HIV clinicStandard of careFollow-upMultilevel mixed modelsOne-month follow-upInjected drugsSix-month follow-upRandomized Controlled TrialsDyad-level factorsSupport interventionsPre-interventionSuboptimal antiretroviral therapyIntervention sessionsART adherenceSupportive partnersHIV clinicNo significant differenceHIV epidemicOral pre-exposure prophylaxis (PrEP) receipt and persistence among opioid-dependent people who inject drugs initiating PrEP for HIV prevention
Khati A, Copenhaver M, Xu R, Altice F, Wickersham J, Gautam K, Paudel K, Shrestha R. Oral pre-exposure prophylaxis (PrEP) receipt and persistence among opioid-dependent people who inject drugs initiating PrEP for HIV prevention. Journal Of Substance Use And Addiction Treatment 2025, 173: 209693. PMID: 40222706, PMCID: PMC12477707, DOI: 10.1016/j.josat.2025.209693.Peer-Reviewed Original ResearchOpioid-dependent PWIDPre-exposure prophylaxisPrEP prescriptionPrEP useInjected drugsOral pre-exposure prophylaxisBehaviours related to sexFollow-up periodOpioid dependencePrEP continuum of careAssociated with higher persistenceFactors associated with persistenceMultivariable ordinal logistic regressionOpioid-dependent peopleDrug useAssess sociodemographic characteristicsPrEP persistenceRelated to sexHIV outbreakContinuum of careEarly 40sParticipantsPrEP continuumHIV preventionHIV
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