2025
Impact of multi-level factors and partner characteristics on antiretroviral therapy adherence and access to HIV care during the COVID-19 pandemic
Neuenschwander P, Pala A, Altice F, Remien R, Mergenova G, Rozental E, Gulyayev V, Davis A. Impact of multi-level factors and partner characteristics on antiretroviral therapy adherence and access to HIV care during the COVID-19 pandemic. International Journal Of STD & AIDS 2025, 36: 568-576. PMID: 40155324, DOI: 10.1177/09564624251329626.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy adherenceMental healthFactors associated with ART adherenceMethodsA cross-sectional surveyMultilevel generalized linear mixed modelsPoor mental healthAssociated with lower adherenceBackgroundAdherence to antiretroviral therapyAntiretroviral therapyMedication adherence ratesCross-sectional surveyCOVID-19 pandemicHIV treatment programsMulti-level factorsNegative emotional impactHIV carePublic health crisisSocial supportART adherenceSupportive partnersLinear mixed modelsAdherence ratesAssessed associationsLow adherenceAdherence levels
2007
Superiority of Directly Administered Antiretroviral Therapy over Self-Administered Therapy among HIV-Infected Drug Users: A Prospective, Randomized, Controlled Trial
Altice FL, Maru DS, Bruce RD, Springer SA, Friedland GH. Superiority of Directly Administered Antiretroviral Therapy over Self-Administered Therapy among HIV-Infected Drug Users: A Prospective, Randomized, Controlled Trial. Clinical Infectious Diseases 2007, 45: 770-778. PMID: 17712763, PMCID: PMC2693907, DOI: 10.1086/521166.Peer-Reviewed Original ResearchConceptsHIV-1 RNA levelsSelf-administered therapyT-lymphocyte countsDrug usersAntiretroviral therapyLymphocyte countRNA levelsPrimary outcomeProportion of patientsGreater mean reductionHIV treatment programsLog10 copies/Human immunodeficiency virusCopies/mLDAART groupVirologic outcomesSecondary outcomesControlled TrialsImmunodeficiency virusPoor adherenceTreatment adherenceEntry criteriaTreat approachCopies/Mean change
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