A Dyad-Based Intervention to Improve Adherence to Antiretroviral Therapy among People with HIV who Inject Drugs in Kazakhstan: Results of a Randomized Controlled Trial
Davis A, Rozental E, Bolger N, Gulyayev V, Gulyayev P, Denebayeva A, Wen H, Cui J, Terlikbayeva A, Primbetova S, Samandas J, Altice F, Remien R, Mergenova G. A Dyad-Based Intervention to Improve Adherence to Antiretroviral Therapy among People with HIV who Inject Drugs in Kazakhstan: Results of a Randomized Controlled Trial. AIDS And Behavior 2025, 1-13. PMID: 40773102, DOI: 10.1007/s10461-025-04841-5.Peer-Reviewed Original ResearchAntiretroviral therapy adherencePost-interventionIntervention armSelf-reported ART adherenceAntiretroviral therapySocial support interventionsImmediately post-interventionLargest HIV clinicStandard of careFollow-upMultilevel mixed modelsOne-month follow-upInjected drugsSix-month follow-upRandomized Controlled TrialsDyad-level factorsSupport interventionsPre-interventionSuboptimal antiretroviral therapyIntervention sessionsART adherenceSupportive partnersHIV clinicNo significant differenceHIV epidemicRationale and design of a randomized clinical trial of integrated eHealth for PrEP and medications for opioid use disorders for women in the criminal legal system. The Athena study
Meyer J, Brunson S, Price C, Mulrain M, Nguyen J, Altice F, Kyriakides T, Cropsey K, Eaton E. Rationale and design of a randomized clinical trial of integrated eHealth for PrEP and medications for opioid use disorders for women in the criminal legal system. The Athena study. Addiction Science & Clinical Practice 2025, 20: 4. PMID: 39825419, PMCID: PMC11742507, DOI: 10.1186/s13722-024-00534-x.Peer-Reviewed Original ResearchConceptsCriminal legal systemOpioid use disorderLegal systemStandard of careStructural barriersUse disorderEnhanced standard of careRates of opioid use disorderDelivery of PrEPPre-exposure prophylaxisWomen's abilityRandomized clinical trialsLife-saving interventionsRandomized Controlled TrialsHealth disparitiesImplementation outcomesPrEP initiationPreventive servicesClinical outcomesIntegrated deliveryFollow-upDelivery modelsClinical trialsDecision aidPrEP
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