2025
Identification and multiply robust estimation in causal mediation analysis across principal strata
Cheng C, Li F. Identification and multiply robust estimation in causal mediation analysis across principal strata. Journal Of The Royal Statistical Society Series B Statistical Methodology 2025, qkaf037. DOI: 10.1093/jrsssb/qkaf037.Peer-Reviewed Original ResearchRobust estimationPrincipal strataJoint potential valuesEfficient influence functionNuisance modelsData examplesEfficient estimationInfluence functionIdentification assumptionsEfficient inferenceEstimationInferenceMisspecificationEstimandsCausal mediation analysisExamplesAssumptionsPosttreatment events
2024
Multiply robust estimation of principal causal effects with noncompliance and survival outcomes
Cheng C, Guo Y, Liu B, Wruck L, Li F, Li F. Multiply robust estimation of principal causal effects with noncompliance and survival outcomes. Clinical Trials 2024, 21: 553-561. PMID: 38813813, DOI: 10.1177/17407745241251773.Peer-Reviewed Original ResearchConceptsPrincipal strataRight-censored survival outcomesPrincipal causal effectsCausal effectsSensitivity analysis strategyPrincipal ignorabilityRobust estimationIdentification assumptionsCensoringPragmatic clinical trialsTreatment assignmentTreatment noncomplianceMonotonicityEstimationAssess treatment effectsCardiovascular diseaseClinical trialsMultipliersTreatment effectsAssumptionsNoncompliance
2021
Clarifying selection bias in cluster randomized trials
Li F, Tian Z, Bobb J, Papadogeorgou G, Li F. Clarifying selection bias in cluster randomized trials. Clinical Trials 2021, 19: 33-41. PMID: 34894795, DOI: 10.1177/17407745211056875.Peer-Reviewed Original ResearchConceptsAverage treatment effectCluster randomized trialPost-randomization selection biasPrincipal strataAnalysis of cluster randomized trialsSelection biasCausal effectsCovariate adjustment methodsData generating processRecruited populationPrincipal stratification frameworkPresence of selection biasHeterogeneous treatment effectsRegression adjustment methodEstimate causal effectsRandomized trialsElectronic health recordsOverall populationEffect heterogeneityIntention-to-treat analysisSimulation studyTreatment effectsEmpirical performanceEstimandsEstimation strategy
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