2025
Model‐Robust Standardization in Cluster‐Randomized Trials
Li F, Tong J, Fang X, Cheng C, Kahan B, Wang B. Model‐Robust Standardization in Cluster‐Randomized Trials. Statistics In Medicine 2025, 44: e70270. PMID: 40968363, DOI: 10.1002/sim.70270.Peer-Reviewed Original ResearchConceptsInformative cluster sizeWorking regression modelsJackknife variance estimatorTreatment effect parametersCluster randomized trialData generating processAverage treatment effectVariance estimationCoefficient estimatesGeneralized linear mixed modelsEstimandsR packageNatural testCluster averagesLinear mixed modelsEstimationTreatment effectsExtensive simulation experimentsCluster sizeInferenceRegression modelsGeneralized Estimating EquationsGeneration processMixed modelsEquations
2022
Clustered restricted mean survival time regression
Chen X, Harhay MO, Li F. Clustered restricted mean survival time regression. Biometrical Journal 2022, 65: e2200002. PMID: 35593026, DOI: 10.1002/bimj.202200002.Peer-Reviewed Original ResearchConceptsSandwich variance estimatorVariance estimatorValid inferencesRegression coefficient estimatesSmall sample scenariosContinuous functionsCluster correlationEffects of covariatesEstimatorHazard functionTarget parametersCoefficient estimatesMultilevel observational studyTime regressionRegression coefficientsInferenceEvent outcomesEquationsRegression modelsModelCritical assumptionsSufficient numberSimulationsFunctionAssumption
2021
Sample size estimation for modified Poisson analysis of cluster randomized trials with a binary outcome
Li F, Tong G. Sample size estimation for modified Poisson analysis of cluster randomized trials with a binary outcome. Statistical Methods In Medical Research 2021, 30: 1288-1305. PMID: 33826454, PMCID: PMC9132618, DOI: 10.1177/0962280221990415.Peer-Reviewed Original ResearchConceptsSample size formulaExchangeable working correlationExtensive Monte Carlo simulation studySize formulaMonte Carlo simulation studyFinite sample correctionMarginal relative riskCorresponding sample size formulaeSandwich variance estimatorVariable cluster sizesNumber of clustersAsymptotic efficiencySandwich varianceCluster size variabilityRobust sandwich varianceSample size estimationVariance estimatorAnalytical derivationSimulation studyCluster sizePoisson modelCoefficient estimatesFormulaCorrelation coefficient estimatesBinary outcomes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply