2023
Informative cluster size in cluster-randomised trials: A case study from the TRIGGER trial
Kahan B, Li F, Blette B, Jairath V, Copas A, Harhay M. Informative cluster size in cluster-randomised trials: A case study from the TRIGGER trial. Clinical Trials 2023, 20: 661-669. PMID: 37439089, PMCID: PMC10638852, DOI: 10.1177/17407745231186094.Peer-Reviewed Original ResearchConceptsCluster-randomised trialCluster-level summariesAcute upper gastrointestinal bleedingExchangeable correlation structureRed blood cell transfusionEQ-5D VAS scoreMixed-effects modelsUpper gastrointestinal bleedingBlood cell transfusionMixed effects modelsTreatment effectsCell transfusionGastrointestinal bleedingIschemic eventsVAS scoresOdds ratioMost outcomesTRIGGER trialTreatment effect estimatesEffect estimatesInformative cluster sizeTrialsOutcomesParticipant outcomesCorrelation structure
2020
Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: An overview
Li F, Hughes JP, Hemming K, Taljaard M, Melnick ER, Heagerty PJ. Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: An overview. Statistical Methods In Medical Research 2020, 30: 612-639. PMID: 32631142, PMCID: PMC7785651, DOI: 10.1177/0962280220932962.Peer-Reviewed Original Research