2023
Incidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty
Weinstein E, Stephens-Shields A, Newcomb C, Silibovsky R, Nelson C, O’Donnell J, Glaser L, Hsieh E, Hanberg J, Tate J, Akgün K, King J, Re V. Incidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty. JAMA Network Open 2023, 6: e2340457. PMID: 37906194, PMCID: PMC10618849, DOI: 10.1001/jamanetworkopen.2023.40457.Peer-Reviewed Original ResearchConceptsPrimary total knee arthroplastyProsthetic joint infectionTotal knee arthroplastyIncidence rate ratiosLate prosthetic joint infectionsPostoperative periodIncidence rateCohort studyOverall cohortJoint infectionKnee arthroplastyVeterans Affairs Surgical Quality Improvement Program dataElective primary total knee arthroplastyEarly prosthetic joint infectionHepatitis C virus infectionQuality Improvement Program dataVeterans Affairs Corporate Data WarehouseAutoimmune inflammatory arthritisPostoperative antibiotic useC virus infectionRisk factor modificationChronic kidney diseasePeripheral artery diseaseLate postoperative periodYears of careAssessing the contributions of modifiable risk factors to serious falls and fragility fractures among older persons living with HIV
Womack J, Murphy T, Leo‐Summers L, Bates J, Jarad S, Gill T, Hsieh E, Rodriguez‐Barradas M, Tien P, Yin M, Brandt C, Justice A. Assessing the contributions of modifiable risk factors to serious falls and fragility fractures among older persons living with HIV. Journal Of The American Geriatrics Society 2023, 71: 1891-1901. PMID: 36912153, PMCID: PMC10258163, DOI: 10.1111/jgs.18304.Peer-Reviewed Original ResearchConceptsModifiable risk factorsFragility fracturesRisk factorsAlcohol use disorderSerious fallsPhysiologic frailtyAntiretroviral therapyOlder PWHUse disordersVeterans Aging Cohort StudyMeasures of multimorbidityAging Cohort StudyBody mass indexMultivariable logistic modelAverage attributable fractionSuccessful prevention programsKey risk factorsOpioid prescriptionsCohort studyMass indexModifiable factorsSixth decadeAttributable fractionElevated riskICD9 codes
2022
Predictive Risk Model for Serious Falls Among Older Persons Living With HIV
Womack JA, Murphy TE, Leo-Summers L, Bates J, Jarad S, Smith AC, Gill TM, Hsieh E, Rodriguez-Barradas MC, Tien PC, Yin MT, Brandt CA, Justice AC. Predictive Risk Model for Serious Falls Among Older Persons Living With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2022, 91: 168-174. PMID: 36094483, PMCID: PMC9470988, DOI: 10.1097/qai.0000000000003030.Peer-Reviewed Original ResearchConceptsMiddle-aged veteransOlder PWHAntiretroviral therapySerious fallsOlder personsVeterans Aging Cohort StudyMeasures of multimorbidityAging Cohort StudyBody mass indexMultivariable logistic regressionPredictive risk modelCohort studyMass indexInjury codesElevated riskGeneral populationSix monthsPWHLogistic regressionPotential predictorsSubstance useRadiology reportsHIVExternal causesVeterans
2021
Brief Report: Are Serious Falls Associated With Subsequent Fragility Fractures Among Veterans Living With HIV?
Womack JA, Murphy TE, Ramsey C, Bathulapalli H, Leo-Summers L, Smith AC, Bates J, Jarad S, Gill TM, Hsieh E, Rodriguez-Barradas MC, Tien PC, Yin MT, Brandt C, Justice AC. Brief Report: Are Serious Falls Associated With Subsequent Fragility Fractures Among Veterans Living With HIV? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 88: 192-196. PMID: 34506360, PMCID: PMC8513792, DOI: 10.1097/qai.0000000000002752.Peer-Reviewed Original ResearchConceptsSubsequent fragility fracturesFragility fracturesAntiretroviral therapySerious fallsRisk factorsVeterans Aging Cohort StudyAging Cohort StudyMultivariable logistic regressionUpper arm fracturesMiddle-aged populationYears of ageAlcohol use disorderCohort studyHip fractureVertebral fracturesArm fracturesInjury codesICD9 codesGeneral populationUse disordersLogistic regressionIntegrase inhibitorsOlder adultsRadiology reportsHIVAging with HIV in Latin America and the Caribbean: a Systematic Review
Cabrera DM, Diaz MM, Grimshaw A, Salvatierra J, Garcia PJ, Hsieh E. Aging with HIV in Latin America and the Caribbean: a Systematic Review. Current HIV/AIDS Reports 2021, 18: 1-47. PMID: 33400168, PMCID: PMC8059362, DOI: 10.1007/s11904-020-00538-7.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesSystematic reviewCommon non-communicable diseasesChronic non-communicable diseasesAntiretroviral treatment programLongitudinal studyPrevalence of illnessPurpose of ReviewWithAge-related findingsChronic comorbiditiesOlder PWHMiddle-income countriesHIVSummaryOur resultsScreening instrumentTreatment programPopulation 40Recent FindingsOfPWHAvailable evidencePeer-reviewed literatureSignificant predictorsComorbiditiesAgeBurdenKnowledge and Impact of COVID-19 on Middle-Aged and Older People Living with HIV in Lima, Peru
Diaz MM, Cabrera DM, Gil-Zacarias M, Ramirez V, Saavedra M, Cárcamo C, Hsieh E, Garcia PJ. Knowledge and Impact of COVID-19 on Middle-Aged and Older People Living with HIV in Lima, Peru. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2021, 20: 23259582211056760. PMID: 34870508, PMCID: PMC8655474, DOI: 10.1177/23259582211056760.Peer-Reviewed Original ResearchConceptsLow educational levelCOVID-19Large HIV clinicMajority of PWHCross-sectional telephone surveyHealthcare systemCOVID-19 symptomsHealth impactsHigher COVID-19 case ratesEducational levelMental health impactCOVID-19 case ratesHIV clinicOlder PWHFemale sexRisk factorsPWHMedical careCase ratesNationwide quarantineOlder peopleVulnerable populationsTelephone surveySocioeconomic supportHIV
2020
Time to sputum culture conversion and its predictors among patients with multidrug-resistant tuberculosis in Hangzhou, China
Li Q, Lu M, Hsieh E, Wu L, Wu Y, Wang M, Wang L, Zhao G, Xie L, Qian HZ. Time to sputum culture conversion and its predictors among patients with multidrug-resistant tuberculosis in Hangzhou, China. Medicine 2020, 99: e23649. PMID: 33327347, PMCID: PMC7738096, DOI: 10.1097/md.0000000000023649.Peer-Reviewed Original ResearchConceptsInitial sputum culture conversionSputum culture conversionPoor treatment outcomesSuccessful treatment outcomeTreatment outcomesCulture conversionMDR-TBMultidrug-resistant tuberculosis patientsCox proportional hazards regressionMDR-TB treatmentMDR-TB patientsRetrospective cohort studyKaplan-Meier methodTreatment success rateInitiation of treatmentMultidrug-resistant tuberculosisProportional hazards regressionConsecutive negative culturesRisk of transmissionCohort studyTuberculosis patientsTreatment failureHazards regressionOutpatient treatmentInpatient treatment
2019
Impact of reference point selection on DXA-based measurement of forearm bone mineral density
Yu W, Ying Q, Guan W, Lin Q, Zhang Z, Chen J, Engelke K, Hsieh E. Impact of reference point selection on DXA-based measurement of forearm bone mineral density. Archives Of Osteoporosis 2019, 14: 107. PMID: 31707587, PMCID: PMC9721067, DOI: 10.1007/s11657-019-0658-2.Peer-Reviewed Original ResearchIncreased Fragility Fracture Rates in Older Men With Osteomyelitis
Hsieh E, Shiau S, Nolan O, Gibert CL, Bedimo RJ, Rodriguez-Barradas MC, Justice AC, Womack JA, Yin MT. Increased Fragility Fracture Rates in Older Men With Osteomyelitis. Clinical Infectious Diseases 2019, 69: 1239-1242. PMID: 30715288, PMCID: PMC6743834, DOI: 10.1093/cid/ciz077.Peer-Reviewed Original Research
2018
Lumbar Vertebrae Morphological Analysis and an Additional Approach for Vertebrae Identification in Lumbar Spine DXA Images
Guan W, Yu W, Lin Q, Zhang Z, Du G, Tian J, Xu Y, Hsieh E. Lumbar Vertebrae Morphological Analysis and an Additional Approach for Vertebrae Identification in Lumbar Spine DXA Images. Journal Of Clinical Densitometry 2018, 23: 395-402. PMID: 30425005, PMCID: PMC6520202, DOI: 10.1016/j.jocd.2018.09.004.Peer-Reviewed Original ResearchConceptsLumbar spine DXA imagesDual-energy X-ray absorptiometrySpine DXA imagesYr of ageDXA imagesAge strataLumbar vertebraeProportion of patientsLarge tertiary hospitalBone mineral densityX-ray absorptiometryDiagnosis of osteoporosisAdult patientsKey anatomic featuresTertiary hospitalMean ageChinese patientsMineral densityBilateral pediclesChi-square analysisLarge cohortProportion of individualsIliac crestPatientsAnatomic featuresHIV-related stigma among people living with HIV/AIDS in rural Central China
Li Z, Morano JP, Khoshnood K, Hsieh E, Sheng Y. HIV-related stigma among people living with HIV/AIDS in rural Central China. BMC Health Services Research 2018, 18: 453. PMID: 29903006, PMCID: PMC6003113, DOI: 10.1186/s12913-018-3245-0.Peer-Reviewed Original ResearchConceptsHIV/AIDSRural PLWHAYoung PLWHAOpportunistic infectionsBerger HIV Stigma ScaleMethodsA cross-sectional studyMultivariable linear regression analysisBurden of HIVDisease-related factorsLevels of HIVCross-sectional studyHIV Stigma ScaleTotal HIVResultsA totalRural central ChinaPoor adherenceChinese PLWHAHIV stigmaHIVPLWHAChinese CenterStigma scoresLinear regression analysisStigma ScaleHigh levelsVertebral fractures among breast cancer survivors in China: a cross-sectional study of prevalence and health services gaps
Hsieh E, Wang Q, Zhang R, Niu X, Xia W, Fraenkel L, Insogna KL, Li J, Smith JS, Zhou C, Qiao YL, Zhang P. Vertebral fractures among breast cancer survivors in China: a cross-sectional study of prevalence and health services gaps. BMC Cancer 2018, 18: 104. PMID: 29378534, PMCID: PMC5789645, DOI: 10.1186/s12885-018-4014-5.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsVertebral fracturesCancer survivorsCross-sectional studyBreast cancerBone lossCancer treatment-induced bone lossHealthy community-dwelling postmenopausal womenProgesterone receptor-positive breast cancerHealth servicesBreast cancer survivor cohortCommunity-dwelling postmenopausal womenFracture-related risk factorsPeking Vertebral Fracture StudyTreatment-induced bone lossReceptor-positive breast cancerChinese breast cancer survivorsCancer survivor cohortLarge cancer hospitalThoracolumbar X-rayVitamin D supplementsPrevalent vertebral fracturesBone density scanInitiation of treatmentAdjusted odds ratio
2016
Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz among individuals with HIV
Hsieh E, Fraenkel L, Han Y, Xia W, Insogna KL, Yin MT, Zhu T, Cheng X, Li T. Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz among individuals with HIV. AIDS 2016, 30: 1935-1942. PMID: 27124896, PMCID: PMC4949136, DOI: 10.1097/qad.0000000000001131.Peer-Reviewed Original ResearchConceptsTenofovir disoproxil fumarateVitamin DProcollagen type 1 N-terminal propeptideInitiation of TDFTenofovir/lamivudine/efavirenzVitamin D binding protein (VDBP) levelsCollagen type 1 cross-linked C-telopeptideIntact parathyroid hormone levelsCross-linked C-telopeptideIntact parathyroid hormoneParathyroid hormone levelsTotal procollagen type 1 N-terminal propeptideBinding protein levelsProtein levelsMulticenter clinical trialPlasma samplesOngoing multicenter clinical trialsN-terminal propeptideClinical characteristicsParathyroid hormoneBone lossFormation markersDisoproxil fumarateC-telopeptideBone resorptionExploring HIV-related stigma among HIV-infected men who have sex with men in Beijing, China: a correlation study
Li Z, Hsieh E, Morano JP, Sheng Y. Exploring HIV-related stigma among HIV-infected men who have sex with men in Beijing, China: a correlation study. AIDS Care 2016, 28: 1394-1401. PMID: 27137205, PMCID: PMC5069196, DOI: 10.1080/09540121.2016.1179713.Peer-Reviewed Original ResearchConceptsHIV transmissionHIV stigmaStigma scoresPoor self-rated health statusBerger HIV Stigma ScaleSelf-rated health statusHIV-positive MSMIncidence of HIVMultivariable linear regression modelsHuman immunodeficiency virusLevels of HIVHIV Stigma ScaleAdverse health outcomesCross-sectional survey studySocial support networksAntiretroviral therapyHIV statusOpportunistic infectionsImmunodeficiency virusPoor adherenceSocio-demographic characteristicsRisk factorsStudy populationHIVHealth outcomes
2014
Increased bone resorption during tenofovir plus lopinavir/ritonavir therapy in Chinese individuals with HIV
Hsieh E, Fraenkel L, Xia W, Hu YY, Han Y, Insogna K, Yin MT, Xie J, Zhu T, Li T. Increased bone resorption during tenofovir plus lopinavir/ritonavir therapy in Chinese individuals with HIV. Osteoporosis International 2014, 26: 1035-1044. PMID: 25224293, PMCID: PMC4334679, DOI: 10.1007/s00198-014-2874-3.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusLopinavir/ritonavirBone turnover markersBone resorption marker levelsResorption marker levelsNon-Chinese populationsAntiretroviral therapyTreatment failureImmunodeficiency virusMarker levelsSkeletal metabolismC-terminal cross-linking telopeptideLopinavir/ritonavir therapyTreatment-naïve patientsFirst-line therapyBone resorption markersProcollagen type 1Multi-center trialPlasma samplesChinese individualsN-terminal propeptideType 1 collagenRitonavir therapyTurnover markersResorption markersBody Mass Index and Breast Cancer Defined by Biological Receptor Status in Pre-Menopausal and Post-Menopausal Women: A Multicenter Study in China
Li J, Huang Y, Zhang BN, Fan JH, Huang R, Zhang P, Wang SL, Zheng S, Zhang B, Yang HJ, Xie XM, Tang ZH, Li H, He JJ, Hsieh E, Qiao YL, Li JY. Body Mass Index and Breast Cancer Defined by Biological Receptor Status in Pre-Menopausal and Post-Menopausal Women: A Multicenter Study in China. PLOS ONE 2014, 9: e87224. PMID: 24489874, PMCID: PMC3906138, DOI: 10.1371/journal.pone.0087224.Peer-Reviewed Original ResearchConceptsBody mass indexPost-menopausal womenHigher Body Mass IndexReceptor statusBreast cancerLogistic regression modelsMass indexBMI dataMultivariate logistic regression modelBreast cancer patientsRank correlation analysisEstrogen metabolism pathwayBreast cancer casesFisher's exact testChi-square testPre-MenopausalMedical chartsPathologic featuresRegression modelsEligible casesMulticenter studyCancer patientsRisk factorsCancer casesExact testEvaluation of routine biopsies in endoscopic screening for esophagogastric junction cancer
Niu X, Wei WQ, Hao CQ, Song GH, Li J, Hua ZL, Li YW, Chang J, Wang XZ, Zhao DL, Wang GQ, Hsieh E, Qiao YL. Evaluation of routine biopsies in endoscopic screening for esophagogastric junction cancer. World Journal Of Gastroenterology 2014, 20: 5074-5081. PMID: 24803821, PMCID: PMC4009543, DOI: 10.3748/wjg.v20.i17.5074.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiopsyCarcinoma in SituChi-Square DistributionChinaCross-Sectional StudiesEndoscopy, Digestive SystemEsophageal NeoplasmsEsophagogastric JunctionFemaleHumansIncidenceLogistic ModelsMaleMiddle AgedMucous MembraneMultivariate AnalysisNeoplasm GradingOdds RatioPredictive Value of TestsStomach NeoplasmsUnnecessary ProceduresConceptsHigh-grade intraepithelial neoplasiaEsophagogastric junction cancerNormal-appearing mucosaPositive pathologic diagnosisHigh-grade lesionsProportion of participantsJunction cancerRoutine biopsyEndoscopic examinationPathologic diagnosisGrade lesionsPathologic resultsMulticenter population-based studyVisible mucosal lesionsPopulation-based studyVisible mucosal abnormalitiesEGJ cancerMucosal lesionsIntraepithelial neoplasiaAbnormal mucosaEndoscopic screeningMucosal abnormalitiesPotential confoundersOdds ratioBiopsy
2006
Sexually transmitted infections and private physicians in Peru, 2003
Hsieh EJ, Blas MM, La Rosa Roca S, Garcia PJ. Sexually transmitted infections and private physicians in Peru, 2003. BULL PAN AM HEALTH ORGAN 2006, 20: 223-229. PMID: 17316480, DOI: 10.1590/s1020-49892006000900002.Peer-Reviewed Original ResearchConceptsPrivate physiciansPrivate practiceCases of STIsPublic health problemInterventional trialsFemale patientsNumber of physiciansPhysician managementSTI casesHealth problemsMedical careDoor surveyPhysician densityMedical officesPhysiciansCities of PeruDemographic informationSTIsPatientsClinical positionsInfectionPhysician workforceMonthsConsultationPublic practice
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