2024
Impact of electronic health record updates and changes on the delivery and monitoring of interventions in embedded pragmatic clinical trials
Marsolo K, Cheville A, Melnick E, Jarvik J, Simon G, Sluka K, Crofford L, Staman K, Richesson R, Schlaeger J, Curtis L. Impact of electronic health record updates and changes on the delivery and monitoring of interventions in embedded pragmatic clinical trials. Contemporary Clinical Trials 2024, 148: 107744. PMID: 39561918, DOI: 10.1016/j.cct.2024.107744.Peer-Reviewed Original ResearchElectronic health record systemsElectronic health recordsPragmatic clinical trialsElectronic health record platformsDelivery of interventionsHealth recordsTrial interventionMonitoring of interventionsRecord updatesStudy teamMonitoring outcomesClinical trialsInterventionLocal implementationTechnological evolutionTeamDynamic natureTrialsDeliveryCase exampleSystem
2022
User centered clinical decision support to implement initiation of buprenorphine for opioid use disorder in the emergency department: EMBED pragmatic cluster randomized controlled trial
Melnick ER, Nath B, Dziura JD, Casey MF, Jeffery MM, Paek H, Soares WE, Hoppe JA, Rajeevan H, Li F, Skains RM, Walter LA, Patel MD, Chari SV, Platts-Mills TF, Hess EP, D'Onofrio G. User centered clinical decision support to implement initiation of buprenorphine for opioid use disorder in the emergency department: EMBED pragmatic cluster randomized controlled trial. The BMJ 2022, 377: e069271. PMID: 35760423, PMCID: PMC9231533, DOI: 10.1136/bmj-2021-069271.Peer-Reviewed Original ResearchConceptsOpioid use disorderUsual care armEmergency departmentUse disordersCare armPragmatic clusterClinical decision supportIntervention armRoutine emergency careSecondary implementation outcomesSeverity of withdrawalTertiary care centerClinical decision support toolInitiation of buprenorphineElectronic health record tasksElectronic health record workflowsRE-AIM frameworkElectronic health record platformsHealth record platformsClinical decision support systemElectronic health recordsVisit documentationTreatment of addictionUsual careAdult patients