2002
Detection of Attenuated, Noninfectious Spirochetes in Borrelia burgdorferi–Infected Mice after Antibiotic Treatment
Bockenstedt LK, Mao J, Hodzic E, Barthold SW, Fish D. Detection of Attenuated, Noninfectious Spirochetes in Borrelia burgdorferi–Infected Mice after Antibiotic Treatment. The Journal Of Infectious Diseases 2002, 186: 1430-1437. PMID: 12404158, DOI: 10.1086/345284.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionSham-treated miceAntibiotic-treated miceBorrelia burgdorferi infectionReal-time polymerase chain reactionIxodes scapularis ticksAntibiotic therapyNaive miceHistopathologic evidenceAntibiotic treatmentBurgdorferi infectionPersistent infectionSpirochete DNAMiceBorrelia burgdorferiMonthsScapularis ticksChain reactionTherapyXenodiagnosisInfectionSpirochetesLimited durationTreatmentLow levels
2001
Infection of Mice with the Agent of Human Granulocytic Ehrlichiosis after Different Routes of Inoculation
Hodzic E, Feng S, Fish D, Leutenegger C, Freet K, Barthold S. Infection of Mice with the Agent of Human Granulocytic Ehrlichiosis after Different Routes of Inoculation. The Journal Of Infectious Diseases 2001, 183: 1781-1786. PMID: 11372031, DOI: 10.1086/320735.Peer-Reviewed Original ResearchConceptsBone marrow samplesReal-time polymerase chain reactionPolymerase chain reactionHuman granulocytic ehrlichiosisMarrow samplesDay 20Granulocytic ehrlichiosisInfection of miceRate of infectionKinetics of infectionLymph nodesGene targetsInfected miceC3H miceEarly disseminationVascular perfusionDay 10Experimental infectionInfectionMiceNeedle inoculationChain reactionBloodEhrlichiosisInoculation