2001
OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks
Tsao J, Barbour A, Luke C, Fikrig E, Fish D. OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks. Vector-Borne And Zoonotic Diseases 2001, 1: 65-74. PMID: 12653137, DOI: 10.1089/153036601750137705.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildAntibodies, BacterialAntigens, SurfaceArachnid VectorsBacterial Outer Membrane ProteinsBacterial VaccinesBorrelia burgdorferiDisease ReservoirsDose-Response Relationship, ImmunologicEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, DirectHost-Parasite InteractionsIxodesLarvaLipoproteinsLyme DiseasePeromyscusConceptsControl miceUninfected larval ticksInfection prevalenceLarval Ixodes scapularis ticksB. burgdorferiNumber of spirochetesEnzyme-linked immunosorbentBorrelia burgdorferi spirochetesLevel of immunizationReservoir hostsConcentration of antibodyBorrelia burgdorferi transmissionIxodes scapularis ticksSecond vaccinationImmunized miceInfected miceLarval ticksPrior infectionVaccination programSubsequent riskDecrease transmissionOspA vaccinationDirect immunofluorescenceImmune responseXenodiagnostic ticks
1993
The distribution of canine exposure to Borrelia burgdorferi in a Lyme-Disease endemic area.
Falco R, Smith H, Fish D, Mojica B, Bellinger M, Harris H, Hechemy K. The distribution of canine exposure to Borrelia burgdorferi in a Lyme-Disease endemic area. American Journal Of Public Health 1993, 83: 1305-1310. PMID: 8363007, PMCID: PMC1694954, DOI: 10.2105/ajph.83.9.1305.Peer-Reviewed Original ResearchConceptsCanine exposureEnzyme-linked immunosorbentLyme diseaseBorrelia burgdorferiLyme disease endemic areaIntensity of exposureHuman Lyme diseaseDistribution of exposureSeroprevalence ratesBlood samplesEndemic areasEquivocal samplesResident dogsWestchester CountyDiseaseMean numberCausative agentSignificant differencesExposureImmunosorbentDogsHuman riskBurgdorferiSimilar patternClose associationCanine Exposure to Borrelia burgdorferi and Prevalence of Ixodes dammini (Acari: Ixodidae) on Deer as a Measure of Lyme Disease Risk in the Northeastern United States
Daniels T, Fish D, Levine J, Greco M, Eaton A, Padgett P, Lapointe D. Canine Exposure to Borrelia burgdorferi and Prevalence of Ixodes dammini (Acari: Ixodidae) on Deer as a Measure of Lyme Disease Risk in the Northeastern United States. Journal Of Medical Entomology 1993, 30: 171-178. PMID: 8433324, DOI: 10.1093/jmedent/30.1.171.Peer-Reviewed Original ResearchConceptsLyme diseaseEndemic areasHuman casesPublic health workersEnzyme-linked immunosorbentCanine exposureHigh-risk countiesNonendemic areasHealth workersCanine seroprevalenceEtiologic agentDisease riskSurveillance programDiseaseBorrelia burgdorferiIxodes damminiCanine serumRegression analysisLyme disease riskPrevalenceSame countyRiskSignificant positive linear relationshipSeroprevalenceImmunosorbentEntomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York.
Schwartz B, Nadelman R, Fish D, Childs J, Forseter G, Wormser G. Entomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York. American Journal Of Tropical Medicine And Hygiene 1993, 48: 50-7. PMID: 8427388, DOI: 10.4269/ajtmh.1993.48.50.Peer-Reviewed Original ResearchConceptsSaliva antibodiesIndependent predictorsI. damminiLate-stage Lyme diseaseStrong independent predictorEnzyme-linked immunosorbentEngorgement indicesErythema migransProspective studyAntibody responseBiologic markersRisk factorsTick biteTick exposureNormal controlsSubject ageLogistic regressionLyme diseaseSalivary glandsOptical density valuesBiteTick engorgementConsistent changesDemographic correlatesAntibodies