Implementation strategies to integrate HIV and hypertension care in Kampala and Wakiso districts, Uganda: study protocol for a stepped wedge cluster randomized trial (PULESA-Uganda)
Longenecker C, Kiggundu J, Ayebare F, Muddu M, Kayima J, Mutungi G, Ssinabulya I, Schwartz J, Spiegelman D, Tong G, Nugent R, Aifah A, Kagoya F, Cameron D, Hutchinson B, Kamya M, Katahoire A, Semitala F. Implementation strategies to integrate HIV and hypertension care in Kampala and Wakiso districts, Uganda: study protocol for a stepped wedge cluster randomized trial (PULESA-Uganda). BMC Health Services Research 2025, 25: 1060. PMID: 40790739, PMCID: PMC12341278, DOI: 10.1186/s12913-025-13281-9.Peer-Reviewed Original ResearchMeSH KeywordsAntihypertensive AgentsCost-Benefit AnalysisDelivery of Health Care, IntegratedHIV InfectionsHumansHypertensionRandomized Controlled Trials as TopicUgandaConceptsCluster randomized trialHypertension careHIV clinicHealth workersWakiso districtStepped-wedge cluster randomized trialRates of HIV viral suppressionImplementation strategiesQuality HIV careClinical health workersBaseline hypertension prevalenceResource intensive strategyFacility-based costsLife expectancy gainsHIV viral suppressionBP controlPatient BP controlHTN careHuman-centered design approachRandomized trialsHIV careImplementation outcomesHypertension prevalencePre-implementationNon-AIDS comorbiditiesEarly findings from the integration of hypertension care into differentiated service delivery models for HIV in Uganda: a mixed‐method study
Kiggundu J, Semitala F, Lipoto C, Giibwa L, Twine R, Mwaka S, Ayebare F, Kiwala C, Magambo E, Mutungi G, Ssinabulya I, Spiegelman D, Kayima J, Muddu M, Schwartz J, Katahoire A, Longenecker C. Early findings from the integration of hypertension care into differentiated service delivery models for HIV in Uganda: a mixed‐method study. Journal Of The International AIDS Society 2025, 28: e26499. PMID: 40622382, PMCID: PMC12232483, DOI: 10.1002/jia2.26499.Peer-Reviewed Original ResearchMeSH KeywordsAdultDelivery of Health CareDelivery of Health Care, IntegratedFemaleHealth PersonnelHIV InfectionsHumansHypertensionMaleMiddle AgedUgandaConceptsHypertension careHealthcare providersExperiences of healthcare providersDSD modelCluster randomised trialRoutine medical recordsInductive thematic analysisGeneralised estimating equationsTime interaction effectsService delivery modelsMixed-methods studyIntegrated careHypertension visitsImplementation researchThematic analysisDelivery modelsPLHIVWakiso districtHypertension managementConsolidation frameworkNational guidelinesQuantitative outcome variablesUganda national guidelinesCareClient education
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