Implementation strategies to integrate HIV and hypertension care in Kampala and Wakiso districts, Uganda: study protocol for a stepped wedge cluster randomized trial (PULESA-Uganda)
Longenecker C, Kiggundu J, Ayebare F, Muddu M, Kayima J, Mutungi G, Ssinabulya I, Schwartz J, Spiegelman D, Tong G, Nugent R, Aifah A, Kagoya F, Cameron D, Hutchinson B, Kamya M, Katahoire A, Semitala F. Implementation strategies to integrate HIV and hypertension care in Kampala and Wakiso districts, Uganda: study protocol for a stepped wedge cluster randomized trial (PULESA-Uganda). BMC Health Services Research 2025, 25: 1060. PMID: 40790739, PMCID: PMC12341278, DOI: 10.1186/s12913-025-13281-9.Peer-Reviewed Original ResearchConceptsCluster randomized trialHypertension careHIV clinicHealth workersWakiso districtStepped-wedge cluster randomized trialRates of HIV viral suppressionImplementation strategiesQuality HIV careClinical health workersBaseline hypertension prevalenceResource intensive strategyFacility-based costsLife expectancy gainsHIV viral suppressionBP controlPatient BP controlHTN careHuman-centered design approachRandomized trialsHIV careImplementation outcomesHypertension prevalencePre-implementationNon-AIDS comorbiditiesEarly findings from the integration of hypertension care into differentiated service delivery models for HIV in Uganda: a mixed‐method study
Kiggundu J, Semitala F, Lipoto C, Giibwa L, Twine R, Mwaka S, Ayebare F, Kiwala C, Magambo E, Mutungi G, Ssinabulya I, Spiegelman D, Kayima J, Muddu M, Schwartz J, Katahoire A, Longenecker C. Early findings from the integration of hypertension care into differentiated service delivery models for HIV in Uganda: a mixed‐method study. Journal Of The International AIDS Society 2025, 28: e26499. PMID: 40622382, PMCID: PMC12232483, DOI: 10.1002/jia2.26499.Peer-Reviewed Original ResearchConceptsHypertension careHealthcare providersExperiences of healthcare providersDSD modelCluster randomised trialRoutine medical recordsInductive thematic analysisGeneralised estimating equationsTime interaction effectsService delivery modelsMixed-methods studyIntegrated careHypertension visitsImplementation researchThematic analysisDelivery modelsPLHIVWakiso districtHypertension managementConsolidation frameworkNational guidelinesQuantitative outcome variablesUganda national guidelinesCareClient educationHarnessing HIV clinics to deliver integrated hypertension care for People living with HIV in Uganda: A formative mixed methods study
Semitala F, Ayebare F, Kiggundu J, Kiwala C, Senfuma J, Mutungi G, Ssinabulya I, Kayima J, Muddu M, Spiegelman D, Schwartz J, Longenecker C, Katahoire A. Harnessing HIV clinics to deliver integrated hypertension care for People living with HIV in Uganda: A formative mixed methods study. PLOS Global Public Health 2025, 5: e0004701. PMID: 40465676, PMCID: PMC12136366, DOI: 10.1371/journal.pgph.0004701.Peer-Reviewed Original ResearchFragmented care deliveryHypertension careQualitative dataHIV clinicSub-Saharan AfricaCare deliveryConsolidated Framework for Implementation ResearchAnalyzed qualitative dataQualitative interviewsInterruptions due to side effectsSub-SaharanHIV servicesBlood pressureHealthcare accessNon-communicable diseasesMixed methods studyUgandaPeri-urban UgandaChronic careSystolic blood pressureHIV careImplementation researchPocket costsMedication accessAnalyzed quantitative data
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply