Featured Publications
Exploiting Gene-Environment Independence for Analysis of Case–Control Studies: An Empirical Bayes-Type Shrinkage Estimator to Trade-Off Between Bias and Efficiency
Mukherjee B, Chatterjee N. Exploiting Gene-Environment Independence for Analysis of Case–Control Studies: An Empirical Bayes-Type Shrinkage Estimator to Trade-Off Between Bias and Efficiency. Biometrics 2007, 64: 685-694. PMID: 18162111, DOI: 10.1111/j.1541-0420.2007.00953.x.Peer-Reviewed Original ResearchConceptsGene-environment independenceShrinkage estimatorsLog odds ratio parametersCase-control dataGene-environment independence assumptionOdds ratio parametersCase-control estimatorsData-adaptive fashionData exampleProspective logistic regression analysisBinary exposureGene-environment associationsIndependence assumptionLogistic regression analysisCase-onlyMaximum likelihood frameworkEstimationSample sizeBinary genesRegression analysisChatterjeeExamplesWeighted averageAssumptions
2020
Interaction analysis under misspecification of main effects: Some common mistakes and simple solutions
Zhang M, Yu Y, Wang S, Salvatore M, Fritsche L, He Z, Mukherjee B. Interaction analysis under misspecification of main effects: Some common mistakes and simple solutions. Statistics In Medicine 2020, 39: 1675-1694. PMID: 32101638, DOI: 10.1002/sim.8505.Peer-Reviewed Original ResearchConceptsType I error rateType I error inflationIndependence assumptionWald and score testsCorrect type I error ratesSandwich variance estimatorSandwich estimatorScore testVariance estimationSimulation studyMisspecificationMichigan Genomics InitiativeStatistical practiceBinary outcomesTested interactionsEmpirical factsFlexible modelData modelTest of interactionBiobank studyInflationAssumptionsContinuous outcomesEpidemiological literatureLinear regression models
2003
Optimal crossover designs under a general model
Bose M, Mukherjee B. Optimal crossover designs under a general model. Statistics & Probability Letters 2003, 62: 413-418. DOI: 10.1016/s0167-7152(03)00050-6.Peer-Reviewed Original Research