2024
Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and their influence on inflammatory biomarkers in pregnancy: Findings from the LIFECODES cohort
Siwakoti R, Harris S, Ferguson K, Hao W, Cantonwine D, Mukherjee B, McElrath T, Meeker J. Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and their influence on inflammatory biomarkers in pregnancy: Findings from the LIFECODES cohort. Environment International 2024, 194: 109145. PMID: 39550829, DOI: 10.1016/j.envint.2024.109145.Peer-Reviewed Original ResearchC-reactive proteinNested case-control study of preterm birthCase-control study of preterm birthInflammatory biomarkersIL-10TNF-aInterquartile range increaseNested case-control studyStudy of preterm birthPre-pregnancy BMIQuantile-based g-computation approachIL-6Prenatal PFAS exposureInflammatory processPregnancy plasma samplesMeasurement of inflammatory biomarkersBirth outcomesLinear mixed modelsInverse associationRange increaseMaternal raceMaternal demographicsTNF-a levelsAdverse pregnancyAfrican Americans
2022
Prediction of telomere length and telomere attrition using a genetic risk score: The multi-ethnic study of atherosclerosis (MESA)
Castro-Diehl C, Smith J, Zhao W, Wang X, Mukherjee B, Seeman T, Needham B. Prediction of telomere length and telomere attrition using a genetic risk score: The multi-ethnic study of atherosclerosis (MESA). Frontiers In Aging 2022, 3: 1021051. PMID: 36304436, PMCID: PMC9592760, DOI: 10.3389/fragi.2022.1021051.Peer-Reviewed Original ResearchMulti-Ethnic Study of AtherosclerosisGenetic risk scoreMulti-Ethnic StudyGenome-wide association studiesStudy of AtherosclerosisAssociated with TLEuropean ancestry genome-wide association studiesEuropean ancestryRisk scoreTL-associated genetic variantsShorter TLEuropean ancestry populationsPredictive of telomere lengthHispanic participantsRace/ethnic groupsLinear mixed effects modelsShorter telomere lengthMixed effects modelsAfrican AmericansTelomere attritionExam 1Association studiesRelative TLTelomere lengthT/S ratio
2021
Exposure and risk factors for COVID-19 and the impact of staying home on Michigan residents
Wu K, Hornsby W, Klunder B, Krause A, Driscoll A, Kulka J, Bickett-Hickok R, Fellows A, Graham S, Kaleba E, Hayek S, Shi X, Sutton N, Douville N, Mukherjee B, Jamerson K, Brummett C, Willer C. Exposure and risk factors for COVID-19 and the impact of staying home on Michigan residents. PLOS ONE 2021, 16: e0246447. PMID: 33556117, PMCID: PMC7870003, DOI: 10.1371/journal.pone.0246447.Peer-Reviewed Original ResearchConceptsAfrican AmericansAnnual household income <Worsening health behaviorsLong-term health outcomesHousehold income <Low socioeconomic statusExposure to family membersHigher overall concernHigh riskExposure to familyHigh risk of contracting COVID-19Positive COVID-19 testLow-income groupsHealth behaviorsHealth outcomesRates of COVID-19 casesRental housingSocioeconomic statusClinical careRisk of contracting COVID-19COVID-19 preventionChronic diseasesInequality gapState of MichiganCOVID-19 cases
2017
Explaining Disparities in Ovarian Cancer Incidence Rates between Women of African and European Ancestry: The Role of Genetic Factors
Mullins M, Mukherjee B, Wu A, Pike M, Pharoah P, Berchuck A, Pearce C. Explaining Disparities in Ovarian Cancer Incidence Rates between Women of African and European Ancestry: The Role of Genetic Factors. Cancer Epidemiology Biomarkers & Prevention 2017, 26: 433-434. DOI: 10.1158/1055-9965.epi-17-0030.Peer-Reviewed Original ResearchGenetic risk scoreOvarian cancer incidence ratesNon-Hispanic White (NHWPopulation attributable risk percentCollaborative Oncological Gene-environment StudyCancer incidence ratesNon-genetic risk factorsIncidence rateAfrican AmericansAssociated with ovarian cancer riskOvarian Cancer Association ConsortiumOophorectomy ratesRisk of ovarian cancerAncestry groupsOvarian cancer riskAttributable risk percentNon-genetic riskGene-environment studiesOvarian cancerSingle nucleotide polymorphismsRisk factorsConditional logistic regressionGRS quintileRisk percentLowest quintile
2015
Association between Stress Response Genes and Features of Diurnal Cortisol Curves in the Multi-Ethnic Study of Atherosclerosis: A New Multi-Phenotype Approach for Gene-Based Association Tests
He Z, Payne E, Mukherjee B, Lee S, Smith J, Ware E, Sánchez B, Seeman T, Kardia S, Roux A. Association between Stress Response Genes and Features of Diurnal Cortisol Curves in the Multi-Ethnic Study of Atherosclerosis: A New Multi-Phenotype Approach for Gene-Based Association Tests. PLOS ONE 2015, 10: e0126637. PMID: 25993632, PMCID: PMC4439141, DOI: 10.1371/journal.pone.0126637.Peer-Reviewed Original ResearchConceptsMulti-Ethnic Study of AtherosclerosisMarker association testsCortisol featuresMulti-Ethnic StudySingle marker association testsStudy of AtherosclerosisAssociation TestGene level association testsGene-based association testsEthnic-specific resultsMeta-analysisGenetic contribution to variabilityGene-level analysisStress-responsive genesSample of European AmericansGenotype-phenotype associationsDiurnal cortisol curveHispanic AmericansChronic diseasesMultiple physiological systemsDaily cortisol profilesAfrican AmericansGene approachGene-basedMultiple testing