2020
Urinary metals and adipokines in midlife women: The Study of Women's Health Across the nation (SWAN)
Wang X, Karvonen-Gutierrez C, Mukherjee B, Herman W, Park S. Urinary metals and adipokines in midlife women: The Study of Women's Health Across the nation (SWAN). Environmental Research 2020, 196: 110426. PMID: 33157106, PMCID: PMC8093324, DOI: 10.1016/j.envres.2020.110426.Peer-Reviewed Original ResearchConceptsStudy of Women's HealthWomen's HealthExposure to cadmiumUrinary metal concentrationsUrinary molybdenumMetal concentrationsMetal exposureSOB-RUrinary metalsNation Multi-Pollutant StudyAssociated with favorable profilesStandard deviation increaseCadmiumLinear regression modelsAdverse adipokine profileMidlife womenLevels of sOB-RHMW adiponectinUrinary cesiumFollow-up visitHuman populationSoluble leptin receptorAdaptive elastic-netSOB-R levelsMetalUrinary metal mixtures and longitudinal changes in glucose homeostasis: The Study of Women’s Health Across the Nation (SWAN)
Wang X, Mukherjee B, Karvonen-Gutierrez C, Herman W, Batterman S, Harlow S, Park S. Urinary metal mixtures and longitudinal changes in glucose homeostasis: The Study of Women’s Health Across the Nation (SWAN). Environment International 2020, 145: 106109. PMID: 32927284, PMCID: PMC7577932, DOI: 10.1016/j.envint.2020.106109.Peer-Reviewed Original ResearchConceptsEnvironmental risk scoreStudy of Women's HealthWomen's HealthExposure to metal mixturesElevated diabetes riskAssociated with lower HOMA-IRUrinary metal mixtureLongitudinal changesMetal mixturesHOMA-BYears of follow-upRate of changeHOMA-IRAdaptive elastic-netStandard deviation increaseDiabetes riskLinear mixed effects modelsLower HOMA-IRRandom interceptMixed effects modelsRisk scoreAssociated with higher HOMA-IRMetal mixture effectsEpidemiological studiesDeviation increase
2018
Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among U.S. adults in NHANES 2003–2014
Wang X, Mukherjee B, Park S. Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among U.S. adults in NHANES 2003–2014. Environment International 2018, 121: 683-694. PMID: 30316184, PMCID: PMC6268112, DOI: 10.1016/j.envint.2018.09.035.Peer-Reviewed Original ResearchConceptsEnvironmental risk scoreAssociated with obesityHeavy metal mixturesHeavy metalsMetal mixturesAssociation of cumulative exposureCumulative exposureComplex survey designEffects of cumulative exposurePhysical activityObesity measuresAdaptive elastic-netChronic conditionsExposure to heavy metalsInteraction of heavy metalsWaist circumferenceTotal body fatNHANES cyclesU.S. adultsEpidemiological researchType 2 diabetes mellitusCorrelated heavy metalSmoking statusHigher BMISkinfold thickness