Adverse fetal and perinatal outcomes associated with Zika virus infection during pregnancy: an individual participant data meta-analysis
Consortium T, Pérez E, Ticona J, Alger J, Aranda C, Niño A, Ansusinha E, Araújo T, Arias J, Nieto L, Ávila M, Bardají A, Mojica C, Benedetti A, Bertozzi A, Bethencourt S, Blackmon K, Aburto V, Brasil P, Brickley E, Britt W, Broutet N, Buekens P, Cabié A, Cabrera-Gaytán D, Cachay R, Cafferata M, Caicedo-Castro I, Calle J, Calvet G, Campbell H, Campos M, Carabali M, Cerigo H, Cordon C, Corrêa J, Costa F, Coutinho C, Cunha A, Cure C, Damen J, Daza M, De la Hoz Siegler I, DeBiasi R, Debray T, de Jong V, Delgado-López C, Duarte G, Miranda G, Eckert V, Eickmann S, Ellis E, Estofolete C, Bolaños L, Fléchelles O, Fong K, Gomes M, Fuller T, Fumadó V, Funk A, Galvão L, Gama G, Gérardin P, Gibbons L, Goncé A, Gonzalez A, Gotuzzo E, Grajales-Muñiz C, Gustafson P, Hamdan T, Harris E, Harrison C, Hcini N, Hofer C, Holband N, Sánchez C, Huerta I, Hurtado I, Inwani I, Isaac D, Jaenisch T, João E, Juliana A, Pereira J, Kara E, Kim C, Ko A, Krebs N, LaBeaud A, Lake-Burger H, Lebov J, Leo Y, Levis B, Lima T, Ling S, Lopez-Medina E, Lorenzo C, Macpherson C, Manders O, Marbán-Castro E, de Azevedo Marques E, Martelli C, Martinez-Espinosa F, González G, Matta G, Máttar S, Maxwell L, McCracken J, Melo A, Menéndez C, Reyes M, Montoya M, de Barros Miranda-Filho D, Montarroyos U, Moons K, Moreira M, Moye J, Mulkey S, Muñoz-Medina J, Munoz J, Mussi-Pinhata M, Negrini S, Nery N, Velásquez J, Nielsen K, Njenga M, Noël T, Nogueira M, Ochoa T, Oliveira C, Osoro E, Souto E, Parra-Saavedra M, Passos S, Rosado L, Coêlho B, Petra P, Pomar L, Prata-Barbosa A, Rabe I, Reis M, Casas A, Rojas D, Rosenberger K, Villarroel P, Clemente N, Cortes M, Sayers J, Scalabrin D, Schuler-Faccini L, Schultz-Cherry S, Segurado A, Short K, Shreedhar P, Silva A, Silva R, Silva V, de Siqueira I, Sohan K, Soriano-Arandes A, Soria-Segarra C, da Costa P, Tami A, Tavares J, Teixeira M, Terry R, Thein T, Thwin S, Tobian F, Rodríguez V, Trejos I, Turchi M, Ugarte-Gil C, Valencia-Prado M, Vallejos-Parás A, Vasconselos Z, da Veiga A, Viñuela-Benéitez C, Vouga M, Wei Y, Westcott J, Widdowson M, Ximenes R, Zorrilla C. Adverse fetal and perinatal outcomes associated with Zika virus infection during pregnancy: an individual participant data meta-analysis. EClinicalMedicine 2025, 83: 103231. PMID: 40630619, PMCID: PMC12235389, DOI: 10.1016/j.eclinm.2025.103231.Peer-Reviewed Original ResearchIPD-MAIPD meta-analysisMeta-analysisIndividual Participant Data Meta-AnalysisPregnant individualsParticipant data meta-analysisInternational health organisationsOne-stage meta-analysisZika virus infectionExploration of heterogeneityRisk of adverse outcomesData Meta-AnalysisWomen of reproductive ageAdverse pregnancy outcomesZika virusRisk of congenital malformationsOutcome prevalenceSurveillance-based studyRelative riskStandardised definitionsHealth OrganisationRisk estimatesMeta-analysesSystematic searchPrimary outcome
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