2025
Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults
Du Z, Pandey A, Moghadas S, Bai Y, Wang L, Matrajt L, Singer B, Galvani A. Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults. Nature Medicine 2025, 31: 647-652. PMID: 39789324, PMCID: PMC11835734, DOI: 10.1038/s41591-024-03431-7.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusSyncytial virusRSV diseaseImpact of vaccinationBurden of respiratory syncytial virusVaccination of pregnant womenRSV-related mortalityProtein-based vaccinesVaccination of older adultsRSV vaccinePregnant womenSeasonal influenzaVaccine uptake ratesInfant hospitalizationClinical trialsPrefusion FHospital costsInfantsHealth burdenAdult immunizationVaccineOlder adultsHospitalEnhanced uptakeHigh-income countries
2020
The implications of silent transmission for the control of COVID-19 outbreaks
Moghadas SM, Fitzpatrick MC, Sah P, Pandey A, Shoukat A, Singer BH, Galvani AP. The implications of silent transmission for the control of COVID-19 outbreaks. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 17513-17515. PMID: 32632012, PMCID: PMC7395516, DOI: 10.1073/pnas.2008373117.Peer-Reviewed Original ResearchConceptsSilent infectionSymptomatic casesAsymptomatic transmissionSilent transmissionPopulation-wide restrictionsRisk of resurgenceRapid contact tracingRecent individual-level dataCoronavirus disease 2019Symptom onsetAsymptomatic proportionAsymptomatic infectionDisease 2019Majority of incidencesPresymptomatic stagePresymptomatic casesInfected individualsContact tracingInfectionFuture outbreaksCOVID-19 outbreakSocial distancing measuresOne-thirdMovement restrictionsDistancing measures
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