2025
Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis
Sumsuzzman D, Ye Y, Wang Z, Pandey A, Langley J, Galvani A, Moghadas S. Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis. BMC Infectious Diseases 2025, 25: 215. PMID: 39948450, PMCID: PMC11827239, DOI: 10.1186/s12879-025-10610-5.Peer-Reviewed Original ResearchConceptsPopulation settingEffective public health strategiesConfidence intervalsImpact of disease severityModified Newcastle-Ottawa ScalePublic health strategiesHigher secondary attack rateRisk of biasNewcastle-Ottawa ScalePandemic responseGlobal systematic reviewRandom-effects modelFreeman-Tukey double arcsine transformationWeb of ScienceNo significant associationDrivers of SARS-CoV-2 transmissionHealth strategiesSecondary attack rateSARS-CoV-2Disease severityEffective pandemic responseTargeted interventionsDouble arcsine transformationOvid MEDLINESystematic reviewImpact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults
Du Z, Pandey A, Moghadas S, Bai Y, Wang L, Matrajt L, Singer B, Galvani A. Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults. Nature Medicine 2025, 31: 647-652. PMID: 39789324, PMCID: PMC11835734, DOI: 10.1038/s41591-024-03431-7.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusSyncytial virusRSV diseaseImpact of vaccinationBurden of respiratory syncytial virusVaccination of pregnant womenRSV-related mortalityProtein-based vaccinesVaccination of older adultsRSV vaccinePregnant womenSeasonal influenzaVaccine uptake ratesInfant hospitalizationClinical trialsPrefusion FHospital costsInfantsHealth burdenAdult immunizationVaccineOlder adultsHospitalEnhanced uptakeHigh-income countries
2024
Estimating the lives that could be saved by expanded access to weight-loss drugs
Pandey A, Ye Y, Wells C, Singer B, Galvani A. Estimating the lives that could be saved by expanded access to weight-loss drugs. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2412872121. PMID: 39405358, PMCID: PMC11513960, DOI: 10.1073/pnas.2412872121.Peer-Reviewed Original ResearchConceptsGlucagon-like peptide-1Body mass index categoriesObesity prevalence dataGlucagon-like peptide-1 receptor agonistsHazard ratio of mortalityRatio of mortalityPublic health impactWeight loss drugsInsurance coverage issuesGastric inhibitory polypeptideHealthcare accessType 2 diabetesUnited StatesPublic health crisisObesity epidemicReceptor agonistsIndex categoriesHazard ratioPrevalence dataInhibitory polypeptidePeptide-1Health impactsNovel treatmentObesityHealth crisisMortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States
Pandey A, Fitzpatrick M, Singer B, Galvani A. Mortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2321494121. PMID: 38648491, PMCID: PMC11066981, DOI: 10.1073/pnas.2321494121.Peer-Reviewed Original Research
2020
The implications of silent transmission for the control of COVID-19 outbreaks
Moghadas SM, Fitzpatrick MC, Sah P, Pandey A, Shoukat A, Singer BH, Galvani AP. The implications of silent transmission for the control of COVID-19 outbreaks. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 17513-17515. PMID: 32632012, PMCID: PMC7395516, DOI: 10.1073/pnas.2008373117.Peer-Reviewed Original ResearchConceptsSilent infectionSymptomatic casesAsymptomatic transmissionSilent transmissionPopulation-wide restrictionsRisk of resurgenceRapid contact tracingRecent individual-level dataCoronavirus disease 2019Symptom onsetAsymptomatic proportionAsymptomatic infectionDisease 2019Majority of incidencesPresymptomatic stagePresymptomatic casesInfected individualsContact tracingInfectionFuture outbreaksCOVID-19 outbreakSocial distancing measuresOne-thirdMovement restrictionsDistancing measures
2016
One Health approach to cost-effective rabies control in India
Fitzpatrick MC, Shah HA, Pandey A, Bilinski AM, Kakkar M, Clark AD, Townsend JP, Abbas SS, Galvani AP. One Health approach to cost-effective rabies control in India. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 14574-14581. PMID: 27994161, PMCID: PMC5187709, DOI: 10.1073/pnas.1604975113.Peer-Reviewed Original ResearchConceptsHuman rabiesRabies deathsCanine vaccinationStray dogsHuman rabies deathsRabies controlCost-effectiveness thresholdPostexposure vaccinationWHO criteriaDog bitesAutopsy dataHealth outcomesHealth approachSurveillance dataVaccinationCost-effective strategyDogsRabiesRabies surveillance dataOne-third
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply