2025
Evaluating community knowledge of tuberculosis preventive therapy in rural South Africa
Foppiano Palacios C, Moll A, Shrestha R, Kompala T, Davis J, Charalambous S, Chimoyi L, Chihota V, Andrews L, Shenoi S. Evaluating community knowledge of tuberculosis preventive therapy in rural South Africa. BMC Public Health 2025, 25: 918. PMID: 40055618, DOI: 10.1186/s12889-025-21719-2.Peer-Reviewed Original ResearchConceptsKnowledge of TBTB knowledgeExploratory factor analysisCommunity membersPublic health educationRural South AfricaCross-sectional studyPreventive therapyTuberculosis preventive therapyMultivariate linear regressionLinear regressionHealth educationChi-square testMedian scoreCounseling effortsCommunity eventsDescriptive statisticsEvaluate knowledgeTesting initiativesCultural beliefsTB incidenceCommunity knowledgeKwaZulu NatalSouth AfricaFactor analysisPrescribing methadone in prison predicts linkage to HIV care after release from prison: A randomized and patient preference trial
Mobley A, Wegman M, Bazazi A, Shenoi S, Bromberg D, Ahmad A, Kamarulzaman A, Altice F. Prescribing methadone in prison predicts linkage to HIV care after release from prison: A randomized and patient preference trial. International Journal Of Drug Policy 2025, 137: 104733. PMID: 39923270, PMCID: PMC11875876, DOI: 10.1016/j.drugpo.2025.104733.Peer-Reviewed Original ResearchConceptsLinkage to HIV careHIV careIncrease linkage to HIV careTreatment-as-prevention strategiesHIV treatment cascadeHIV treatment outcomesOpen-label trialCox proportional hazards modelsPatient preference trialOpioid use disorderMalaysia’s largest prison.Impact of methadoneProportional hazards modelTreatment cascadeInverse probability weighted Cox proportional hazards modelAnalytic sampleStudy participantsCareTreatment outcomesPrescribed methadoneOpioidConfounding variablesHIVUse disorderHazards modelP-511. Missed Opportunities for Pre-Exposure Prophylaxis Initiation in Hospitalized Persons with Opioid Use Disorder and Infectious Diseases
Parchinski K, Neirinckx V, Di Paola A, Ghantous T, Tarfa A, Shenoi S, Strong M, Roth P, Levin F, Brady K, Nunes E, Frank C, Litwin A, Springer S. P-511. Missed Opportunities for Pre-Exposure Prophylaxis Initiation in Hospitalized Persons with Opioid Use Disorder and Infectious Diseases. Open Forum Infectious Diseases 2025, 12: ofae631.710. PMCID: PMC11779160, DOI: 10.1093/ofid/ofae631.710.Peer-Reviewed Original ResearchOpioid use disorderPerceived risk of HIVRisk of HIVHIV infectionLow risk of HIV infectionRisk factorsModerate to severe opioid use disorderRisk of HIV infectionLong-acting injectable buprenorphinePrevent HIV acquisitionCo-occurring infectionsSevere opioid use disorderPre-exposure prophylaxis initiationHIV risk factorsCondomless sexual intercourseRetrospective data analysisHIV prevention carePre-exposure prophylaxisHIV risk behaviorsIncrease PrEP uptakeAdmission to hospitalAntiretroviral therapyHIV acquisitionProphylaxis initiationHIV testingP-1402. Will You Receive HIV and HCV Testing from a Mobile Pharmacy? Pre-implementation Needs Assessment and Pilot Findings from the United States First Legal Retail Mobile Pharmacy
Tarfa A, Frank C, Brooks R, Schultheis A, Di Paola A, Shenoi S, Springer S. P-1402. Will You Receive HIV and HCV Testing from a Mobile Pharmacy? Pre-implementation Needs Assessment and Pilot Findings from the United States First Legal Retail Mobile Pharmacy. Open Forum Infectious Diseases 2025, 12: ofae631.1577. PMCID: PMC11779293, DOI: 10.1093/ofid/ofae631.1577.Peer-Reviewed Original ResearchCommunity health workersMobile pharmaciesOpioid use disorderAlcohol use disorderHIV testingPre-implementationSubstance use disordersNeeds assessmentNavigating health care systemsCare delivery modelsHCV testingHealth care systemProviding health servicesRisk of HIVUse disorderMD-MPHAccessing careHealth workersService useCharacterize barriersHealth screeningHealth servicesPharmacy servicesHealth careCare system“Men Take Care of Each Other”: Evaluation of a Community-Based Model for Pre-exposure Prophylaxis Services Among Male Bar Patrons in Rural South Africa
Chen P, Nkosi S, Moll A, Braithwaite R, Ngubane S, Shenoi S. “Men Take Care of Each Other”: Evaluation of a Community-Based Model for Pre-exposure Prophylaxis Services Among Male Bar Patrons in Rural South Africa. AIDS Patient Care And STDs 2025, 39: 3-11. PMID: 39761130, PMCID: PMC11839517, DOI: 10.1089/apc.2024.0154.Peer-Reviewed Original ResearchConceptsMale nursesAlcohol-serving venuesPrEP servicesHIV servicesHIV testingSocial supportHIV service delivery modelsAlcohol useNurse follow-upAlcohol-associated riskAvoidance of stigmaCommunity-based modelRural South AfricaService delivery modelsPre-exposure prophylaxisMale bar patronsPatient ambassadorsCommunity nursesNursing assistantsPrEP disclosurePrEP initiationHome visitsSouth AfricaPost-pilotClinic attendance
2024
Cost-effectiveness of screening and treating alcohol use and depression among people living with HIV in Zimbabwe: a mathematical modeling study
Su J, Yeo Y, Jeetoo M, Morojele N, Francis J, Shenoi S, Braithwaite R. Cost-effectiveness of screening and treating alcohol use and depression among people living with HIV in Zimbabwe: a mathematical modeling study. BMC Medicine 2024, 22: 481. PMID: 39428460, PMCID: PMC11492560, DOI: 10.1186/s12916-024-03674-8.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyBackgroundAlcohol use disorderTreating alcohol useCompared to baselineLong-acting PrEPDepressive disorderTreat AUDUse disorderMDDMDD screeningAlcohol usePHQ-9Quality-adjusted life yearsAUDCost-effectiveness of screeningSub-Saharan African settingDisordersImpact of screeningIntervention costsHIV infectionHIV transmissionHIV reductionInterventionHIV outcomesHIV epidemicBurden of tuberculosis in underserved populations in South Africa: A systematic review and meta-analysis
Holtgrewe L, Johnson A, Nyhan K, Boffa J, Shenoi S, Karat A, Davis J, Charalambous S. Burden of tuberculosis in underserved populations in South Africa: A systematic review and meta-analysis. PLOS Global Public Health 2024, 4: e0003753. PMID: 39361564, PMCID: PMC11449336, DOI: 10.1371/journal.pgph.0003753.Peer-Reviewed Original ResearchLatent TB infection prevalenceLatent TB infectionUnderserved populationsTB prevalenceMeta-analysisSystematic reviewNational averagePrevalence of TB diseaseCalculate prevalence ratiosTB diseaseCase-finding strategiesPopulation of personsAssessed study qualityHigh TB prevalenceHigh-burden countriesBurden of tuberculosisTB interventionsPrevalence ratiosStudy qualityReduce tuberculosisHIV statusActive TB diseaseGeneral populationModerate heterogeneityTB incidencePrior tuberculosis, radiographic lung abnormalities and prevalent diabetes in rural South Africa
Castle A, Moosa Y, Claassen H, Shenoi S, Magodoro I, Manne-Goehler J, Hanekom W, Bassett I, Wong E, Siedner M. Prior tuberculosis, radiographic lung abnormalities and prevalent diabetes in rural South Africa. BMC Infectious Diseases 2024, 24: 690. PMID: 38992607, PMCID: PMC11238449, DOI: 10.1186/s12879-024-09583-8.Peer-Reviewed Original ResearchConceptsPrevalent diabetesChest X-rayChest X-ray abnormalitiesX-ray abnormalitiesOdds of prevalent diabetesHemoglobin A1c testingPost-TB lung diseaseHistory of TB diseaseAssociated with prevalent diabetesPulmonary abnormalitiesExposure of interestRural South AfricaPrevalence of diabetesTB diseaseCohort of peopleCAD4TBMethodsWe analyzed dataCross-sectional studyCompare groupsLogistic regression modelsIncidence of diabetesDiabetes prevalenceA1c testingConclusionsAmong peopleDigital chest X-rayConsiderations when prescribing opioid agonist therapies for people living with HIV
Tarfa A, Lier A, Shenoi S, Springer S. Considerations when prescribing opioid agonist therapies for people living with HIV. Expert Review Of Clinical Pharmacology 2024, 17: 549-564. PMID: 38946101, PMCID: PMC11299801, DOI: 10.1080/17512433.2024.2375448.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidAnti-HIV AgentsBuprenorphineDelayed-Action PreparationsDelivery of Health CareDrug InteractionsHealth Services AccessibilityHIV InfectionsHumansMethadoneNaltrexoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPre-Exposure ProphylaxisUnited StatesConceptsOpioid agonist therapyOpioid use disorderAntiretroviral therapyAgonist therapyDiagnosed OUDOpioid use disorder managementUse disorderTreatment of opioid use disorderExtended-release naltrexonePotential drug interactionsOpioid use disorder treatmentPrescribed opioid agonist therapyLong-acting formulationPre-exposure prophylaxisOUD outcomesImprove HIV preventionIntersection of HIVOpioid antagonistHIV outcomesHIV epidemicOpioidHIVOpioid use disorder servicesPWHHIV preventionHIV and Substance Use Disorders
Lier A, Tarfa A, Shenoi S, Kuo I, Springer S. HIV and Substance Use Disorders. Infectious Disease Clinics Of North America 2024, 38: 599-611. PMID: 38960783, PMCID: PMC11410345, DOI: 10.1016/j.idc.2024.06.003.Peer-Reviewed Original ResearchHuman immunodeficiency virusSubstance use disordersEvidence-based public health effortsHuman immunodeficiency virus acquisitionHuman immunodeficiency virus incidenceRisk of HIV acquisitionUntreated substance use disordersPoor HIV outcomesAdherence to HIV antiretroviral therapyHIV antiretroviral therapyPublic health effortsInjection drug useAntiretroviral therapyHIV acquisitionImmunodeficiency virusHIV outcomesHealth effortsTreatment strategiesIncreased riskDrug useSubstance useDrugAmericanRiskPersonsMissed Opportunities for Preexposure Prophylaxis Initiation in Hospitalized Persons With Opioid Use Disorder and Infectious Diseases
Parchinski K, Neirinckx V, Frank C, Di Paola A, Tarfa A, Shenoi S, Vander WyK B, Roth P, Ghantous T, Wegman M, Strong M, Levin F, Brady K, Nunes E, Litwin A, Springer S. Missed Opportunities for Preexposure Prophylaxis Initiation in Hospitalized Persons With Opioid Use Disorder and Infectious Diseases. Open Forum Infectious Diseases 2024, 11: ofae366. PMID: 39022389, PMCID: PMC11252843, DOI: 10.1093/ofid/ofae366.Peer-Reviewed Original ResearchCauses, risks and care circumstances associated with death in older adults diagnosed with HIV in a tertiary centre in Malaysia
Wong H, Li W, Kahar M, Chong M, Shenoi S, Rozanova J, Omar S, Neelamegam M, Lee Y, Rajasuriar R. Causes, risks and care circumstances associated with death in older adults diagnosed with HIV in a tertiary centre in Malaysia. International Journal Of STD & AIDS 2024, 35: 710-720. PMID: 38722271, DOI: 10.1177/09564624241250378.Peer-Reviewed Original ResearchOlder adultsART initiationCox proportional multivariate modelsFactors associated with all-cause mortalityOlder ageRisk factorsAIDS-relatedIndependent factors associated with deathAll-cause mortalityFactors associated with deathHIV diagnosisCare circumstancesAssociated with deathChronic comorbiditiesOlder individualsCareIndependent risk factorAnalysed dataAge groupsMultivariate modelAdultsTertiary centreHIVOpportunistic infectionsAgeUkrainian healthcare providers under siege during the first year of war: challenges and adaptations
Deac A, Zaviryukha I, Zeziulin O, Peycheva A, de Souza R, Skipper H, Abubakar A, Gustilo V, Shenoi S, Thornicroft G, Rozanova J. Ukrainian healthcare providers under siege during the first year of war: challenges and adaptations. BJPsych International 2024, 21: 35-37. PMID: 38693956, PMCID: PMC11035963, DOI: 10.1192/bji.2023.43.Peer-Reviewed Original ResearchHealthcare workers' mental healthFront-line healthcare workersPsychosocial support servicesWorkers' mental healthPre-existing difficultiesHealthcare providersHealthcare reformMental healthHealthcare workersJob retentionSupport servicesExpert consultationMedical documentationWell-beingHealthcarePanel discussionCOVID-19ProvidersHealthConsultationCliniciansCOVID-19 crisisYears of warWorkersServicesHigher methadone dose at time of release from prison predicts linkage to maintenance treatment for people with HIV and opioid use disorder transitioning to the community in Malaysia
Ahmad A, Bromberg D, Shrestha R, Salleh N, Bazazi A, Kamarulzaman A, Shenoi S, Altice F. Higher methadone dose at time of release from prison predicts linkage to maintenance treatment for people with HIV and opioid use disorder transitioning to the community in Malaysia. International Journal Of Drug Policy 2024, 126: 104369. PMID: 38484531, PMCID: PMC11056294, DOI: 10.1016/j.drugpo.2024.104369.Peer-Reviewed Original ResearchMethadone maintenance treatmentNational Institute of Drug AbuseMethadone dosePost-releaseOpioid dependenceMaintenance treatmentMethadone maintenance treatment doseHigher doses of methadoneProspective trialsHighest methadone dosagePost-release outcomesHigher methadone dosesMalaysia’s largest prison.Levels of depressionTreatment of opioid use disorderMonths of releaseDose of methadoneOpioid use disorderLargest prisonHigher dosageIncarcerated peopleIncarceration periodUse disorderMethadone dosageTime-to-event analysis
2023
MENTAL HEALTH VULNERABILITIES AND STRENGTHS OF OLDER WOMEN WITH HIV DURING THE HUMANITARIAN CRISIS IN UKRAINE
Rozanova J, Shenoi S, Zeziulin O, Rich K, Bromberg D, Kiriazova T, Deac A, Earnshaw V. MENTAL HEALTH VULNERABILITIES AND STRENGTHS OF OLDER WOMEN WITH HIV DURING THE HUMANITARIAN CRISIS IN UKRAINE. Innovation In Aging 2023, 7: 137-137. PMCID: PMC10737039, DOI: 10.1093/geroni/igad104.0449.Peer-Reviewed Original ResearchSubstance use disordersHIV diagnosisChronic conditionsDepressive symptomsComorbid substance use disorderAnxiety symptomsSocial supportLikelihood of anxietyMixed effects logistic regression modelsEffects logistic regression modelsLogistic regression modelsMental health vulnerabilitiesPsychological counselingPrimary outcomeLongitudinal cohortHIV disclosureUse disordersSevere anxietySymptomsOlder individualsOlder peopleLogistical regressionMental healthCOVID-19HIVHuman costs of healthcare resilience during the war in Ukraine: Lessons from addiction and HIV treatment
Rozanova J, Zaviryukha I, Deac A, Zeziulin O, Kiriazova T, Earnshaw V, Rich K, Shenoi S, Skipper H, Yariy V, Strang J. Human costs of healthcare resilience during the war in Ukraine: Lessons from addiction and HIV treatment. Addiction 2023, 119: 980-983. PMID: 38130082, DOI: 10.1111/add.16406.Peer-Reviewed Original Research1901. High Prevalence of Latent Tuberculosis Infection in a Malaysian Prison
Zhang L, Shenoi S, Kamarulzaman A, Dhaliwal S, Ahmad A, Altice F. 1901. High Prevalence of Latent Tuberculosis Infection in a Malaysian Prison. Open Forum Infectious Diseases 2023, 10: ofad500.1729. PMCID: PMC10677608, DOI: 10.1093/ofid/ofad500.1729.Peer-Reviewed Original ResearchLatent tuberculosis infectionPrevalence of LTBIRisk of LTBITB preventive therapyIndependent risk factorTuberculin skin testC-reactive proteinActive TBPreventive therapyTuberculosis infectionRisk factorsHigh prevalenceMultivariable logistic regressionOpioid use disorderRisk of hepatotoxicityChest X-rayDrug use historyPaucity of dataLTBI treatmentHCV infectionHepatitis CHepatitis BMedian ageBlood testsSkin testPrioritizing persons deprived of liberty in global guidelines for tuberculosis preventive treatment
Narayan A, Salindri A, Keshavjee S, Muyoyeta M, Velen K, Rueda Z, Croda J, Charalambous S, García-Basteiro A, Shenoi S, Gonçalves C, da Silva L, Possuelo L, Aguirre S, Estigarribia G, Sequera G, Grandjean L, Telisinghe L, Herce M, Dockhorn F, Altice F, Andrews J. Prioritizing persons deprived of liberty in global guidelines for tuberculosis preventive treatment. PLOS Medicine 2023, 20: e1004288. PMID: 37788448, PMCID: PMC10547494, DOI: 10.1371/journal.pmed.1004288.Peer-Reviewed Original ResearchIntegrated Care Models: HIV and Substance Use
Hill K, Kuo I, Shenoi S, Desruisseaux M, Springer S. Integrated Care Models: HIV and Substance Use. Current HIV/AIDS Reports 2023, 20: 286-295. PMID: 37698755, PMCID: PMC11034717, DOI: 10.1007/s11904-023-00667-9.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersSubstance useIntegrated careRecent HIV outbreaksHIV viral suppressionMultidisciplinary care teamHIV virologic suppressionOpioid use disorderRisk of HIVHarm reduction programsSubstance use treatmentEvidence-based strategiesVirologic suppressionViral suppressionHIV outbreakCare teamProvider trainingHIVOnward transmissionHealth outcomesCare servicesClinic leadershipCare integrationMedical literatureTreatment System Adaptations during War: Lessons from Ukrainian Addiction Treatment Providers
Deac A, Zaviryukha I, Rozanova J, Zeziulin O, Kiriazova T, Shenoi S, Peycheva A, de Souza R, Skipper H, Abubakar A, Gustilo V, Thornicroft G, Dellamura P, Rich K, Earnshaw V, Bromberg D, Mamedova E, Yariy V. Treatment System Adaptations during War: Lessons from Ukrainian Addiction Treatment Providers. Substance Use & Misuse 2023, 58: 1447-1450. PMID: 37317994, PMCID: PMC10527686, DOI: 10.1080/10826084.2023.2212377.Peer-Reviewed Original ResearchConceptsHIV/AIDSSustainable capacity buildingDynamics of warCapacity buildingHumanitarian contextsHealth service deliveryService deliveryWarMental health service deliveryVulnerable groupsContextual threatMental health needsUkraineHealth needsHealthcare providersMental health servicesPatient policyRelocation strategyLessonsWellbeingHealth servicesTreatment providersWorkersHealthcare systemSecond half
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