2025
Associations between blood donors, component modifications, and the alloimmunization of transfusion recipients
Yu H, Karafin M, Tormey C, Goel R, Spencer B, Hendrickson J, Hauser R. Associations between blood donors, component modifications, and the alloimmunization of transfusion recipients. Transfusion 2025 PMID: 39821794, DOI: 10.1111/trf.18135.Peer-Reviewed Original ResearchRisk of RBC alloimmunizationRed blood cell unitsRed blood cellsTransfusion recipientsBlood donorsRBC alloimmunizationMultivariate conditional logistic regression analysisConditional logistic regression analysisRisk of alloimmunizationIrradiated red blood cellsCase-control studyLogistic regression analysisSickle cell diseaseAlloantibody formationAlloimmunization eventsRecipient variablesAlloimmunizationRecipient EpidemiologyRecipient diagnosisSub-analysisDecreased riskCell diseaseOlder donorsLow riskTransfusion
2024
Decreasing alloimmunization‐specific mortality in sickle cell disease in the United States: Cost‐effectiveness of a shared transfusion resource
Ito S, Pandya A, Hauser R, Krishnamurti L, Stites E, Tormey C, Krumholz H, Hendrickson J, Goshua G. Decreasing alloimmunization‐specific mortality in sickle cell disease in the United States: Cost‐effectiveness of a shared transfusion resource. American Journal Of Hematology 2024, 99: 570-576. PMID: 38279581, DOI: 10.1002/ajh.27211.Peer-Reviewed Original ResearchSickle cell diseaseDelayed hemolytic transfusion reactionQuality-adjusted life expectancyAlloimmunized patientsPatient populationRed blood cell alloimmunizationCell diseaseCost-effective interventionMedical expenditure of patientsHealth system perspectiveExpenditure of patientsIncremental cost-effectiveness ratioHemolytic transfusion reactionsUnited StatesMarkov cohort simulationCost-effectiveAverage patient populationCost-effectiveness ratioBirth cohortAnalytical time horizonAntibody historyCohort simulationTransfusionTransfusion reactionsLife expectancy
2022
A US-Wide Red Blood Cell Alloantibody Exchange Can Decrease Mortality and Produce Cost Savings in the Care of Alloimmunized Patients with Sickle Cell Disease
Goshua G, Hauser R, Tormey C, Pandya A, Hendrickson J. A US-Wide Red Blood Cell Alloantibody Exchange Can Decrease Mortality and Produce Cost Savings in the Care of Alloimmunized Patients with Sickle Cell Disease. Blood 2022, 140: 2147-2148. DOI: 10.1182/blood-2022-169099.Peer-Reviewed Original Research