2025
Associations between blood donors, component modifications, and the alloimmunization of transfusion recipients
Yu H, Karafin M, Tormey C, Goel R, Spencer B, Hendrickson J, Hauser R. Associations between blood donors, component modifications, and the alloimmunization of transfusion recipients. Transfusion 2025 PMID: 39821794, DOI: 10.1111/trf.18135.Peer-Reviewed Original ResearchRisk of RBC alloimmunizationRed blood cell unitsRed blood cellsTransfusion recipientsBlood donorsRBC alloimmunizationMultivariate conditional logistic regression analysisConditional logistic regression analysisRisk of alloimmunizationIrradiated red blood cellsCase-control studyLogistic regression analysisSickle cell diseaseAlloantibody formationAlloimmunization eventsRecipient variablesAlloimmunizationRecipient EpidemiologyRecipient diagnosisSub-analysisDecreased riskCell diseaseOlder donorsLow riskTransfusion
2019
The Presence and Persistence of Pregnancy-Associated Red Blood Cell Alloantibodies in Blood Donors
Balbuena-Merle R, Hauser R, Karafin M, Tan S, Spencer B, Roubinian N, Wu Y, Triulzi D, Kleinman S, Gottschall J, Tormey C, Hendrickson J. The Presence and Persistence of Pregnancy-Associated Red Blood Cell Alloantibodies in Blood Donors. Blood 2019, 134: 2452. DOI: 10.1182/blood-2019-121388.Peer-Reviewed Original ResearchRBC alloantibodiesTransfusion historyBlood donorsBlood donor databasePregnant femalesPersistent antibodiesPrior transfusionsPrior pregnancyAntibody screenMean durationPregnancy historyFemale healthy blood donorsRed blood cell alloantibodiesDonor databaseMean timeAntibody screen resultsHealthy blood donorsUS blood centersSubsequent donationsMajority of donorsSubsequent blood donationsAlloantibody specificitiesRBC alloimmunizationCell microchimerismAntigen exposure