2024
Modelling the epidemiological and economic impact of digital adherence technologies with differentiated care for tuberculosis treatment in Ethiopia
Goscé L, Tadesse A, Foster N, van Kalmthout K, van Rest J, van der Wal J, Harker M, Madden N, Abdurhman T, Gadissa D, Bedru A, Dube T, Alacapa J, Mganga A, Deyanova N, Charalambous S, Letta T, Jerene D, White R, Fielding K, Houben R, McQuaid C. Modelling the epidemiological and economic impact of digital adherence technologies with differentiated care for tuberculosis treatment in Ethiopia. BMJ Global Health 2024, 9: e016997. PMID: 39653521, PMCID: PMC11628985, DOI: 10.1136/bmjgh-2024-016997.Peer-Reviewed Original ResearchConceptsDigital adherence technologiesHealthcare providersTB deathsPatient cost savingsStandard of careAdherence technologiesLabelling interventionsEpidemiological impactASCENT trialDifferentiated careMedication labelsIncident TBImprove tuberculosisProvider costsTB incidenceCareTB episodeProvidersCompartmental transmission modelPotential long-termCost of treatmentInterventionTreatment completionHealthcareEpidemiological benefits
2023
“It’s about time they taught us”: a qualitative study evaluating the barriers to finding and screening child contacts under five at risk for TB in Gauteng Province, South Africa from the provider and caregiver perspectives
Munedzimwe F, Chetty-Makkan C, Mukora R, Charalambous S, Turner K, Chihota V. “It’s about time they taught us”: a qualitative study evaluating the barriers to finding and screening child contacts under five at risk for TB in Gauteng Province, South Africa from the provider and caregiver perspectives. BMC Health Services Research 2023, 23: 1415. PMID: 38102646, PMCID: PMC10722712, DOI: 10.1186/s12913-023-10359-0.Peer-Reviewed Original ResearchConceptsTB preventive treatmentTB prevention strategiesIsoniazid preventive therapyTB staffSemi-structured questionnaireTB transmissionFacility staffPrevention strategiesPrimary health clinicsPrevention of tuberculosisEnd TB goalChild contactsYears of ageFacility observationsSemi-structured interview guidePreventive therapyTB preventionTB screeningTB treatmentPreventive servicesPreventive treatmentEkurhuleni DistrictHealth clinicsHigh riskCaregiver perspectivesImpact of youth lay health workers on HIV service delivery in South Africa: A pragmatic cluster randomized trial of the Youth Health Africa program
Tollefson D, Dasgupta S, Setswe G, Reeves S, Charalambous S, Duerr A. Impact of youth lay health workers on HIV service delivery in South Africa: A pragmatic cluster randomized trial of the Youth Health Africa program. PLOS ONE 2023, 18: e0294719. PMID: 38033029, PMCID: PMC10688901, DOI: 10.1371/journal.pone.0294719.Peer-Reviewed Original ResearchConceptsHIV service deliveryHIV testingTreatment initiationIntervention facilitiesHealth workersYoung adultsAdolescents/young adultsProportion of patientsPragmatic clusterSecondary outcomesHIV positivityPrimary outcomeTreat analysisHIV servicesHIV programsHealth facilitiesHIVBaseline outcomesTrialsService deliveryNull trialsCareImmediate increaseOutcomesGreater improvement