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DTSTART:20241103T020000
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DESCRIPTION:NOTE: BIS 526 students are required to attend in person (47 Co
 llege St.\, Room 106A). All others are requested to attend via Zoom. Spea
 ker- Donna L. Coffman\, Ph.D. Title- "A causal approach to functional med
 iation analysis with application to a smoking cessation intervention" Abs
 tract The increase in the use of mobile and wearable devices now allow de
 nse assessment of mediating processes over time. For example\, a pharmaco
 logical intervention may have an effect on smoking cessation via reductio
 ns in momentary withdrawal symptoms. We define and identify the causal di
 rect and indirect effects in terms of potential outcomes on the mean diff
 erence and odds ratio scales and present a method for estimating and test
 ing the indirect effect of a randomized treatment on a distal binary vari
 able as mediated by the nonparametric trajectory of an intensively measur
 ed longitudinal variable (e.g.\, from ecological momentary assessment). C
 overage of a bootstrap test for the indirect effect is demonstrated via s
 imulation. An empirical example is presented based on estimating later sm
 oking abstinence from patterns of craving during smoking cessation treatm
 ent. We provide an R package\, funmediation\, to conveniently apply this 
 technique. We conclude by discussing possible extensions to multiple medi
 ators and directions for future research. The paper on which the talk is 
 based can be found here: https://arxiv.org/abs/2112.03960\n\nSpeaker:\nDo
 nna L. Coffman\n\nAdmission:\nFree\n\nDetails URL:\nhttps://medicine.yale
 .edu/event/ysph-biostatistics-seminar-tbn-222/\n
DTEND;TZID=America/New_York:20220222T130000
DTSTAMP:20261021T062559Z
DTSTART;TZID=America/New_York:20220222T120000
GEO:41.302961;-72.931638
LOCATION:106A\, 47 College Street\, New Haven\, CT\, United States
SEQUENCE:0
STATUS:Confirmed
SUMMARY:YSPH Biostatistics Seminar- "A Causal Approach to Functional Media
 tion Analysis with Application to a Smoking Cessation Intervention"
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