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DTSTART:20241103T020000
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DESCRIPTION:This study aims to evaluate implementation—specifically reach\
 , adoption\, fidelity\, and maintenance—and effectiveness in reducing blo
 od pressure through implementation strategies that enhance uptake of a co
 mmunity-based hypertension control intervention in Nepal. The study uses 
 a hybrid type III effectiveness–implementation trial design\, with a prim
 ary focus on Reach\, Effectiveness\, Adoption\, Implementation\, and Main
 tenance (RE-AIM) outcomes. We conduct a cluster-randomized trial in Sindh
 upalchowk District\, randomizing 102 health facilities into the Community
 -based Hypertension Prevention and Control (CHPC) intervention group (n =
  52) and the standard care control group (n = 50).The CHPC intervention i
 ncludes community-based blood pressure monitoring\, lifestyle counseling\
 , and medication adherence monitoring\, supported by implementation strat
 egies that include leadership support and ongoing program promotion\; cap
 acity building of healthcare workers and Female Community Health Voluntee
 rs in hypertension management\; FCHV group meetings and home visits\; and
  the creation of social networks to promote shared learning. We recruit 3
 \,572 participants (35 per cluster) aged ≥30 years with blood pressure ≥1
 40/90 mmHg and/or current antihypertensive medication use\, and we compar
 e outcomes between intervention and control communities.We assess impleme
 ntation outcomes using mixed-methods process evaluation data from interve
 ntion health facilities\, evaluate effectiveness by comparing mean systol
 ic blood pressure reduction between groups 12 months after intervention i
 nitiation\, and assess cost-effectiveness. We further examine implementat
 ion processes through observations\, periodic reflections\, focus group d
 iscussions\, and key informant interviews\, with qualitative data collect
 ion informed by the Consolidated Framework for Implementation Research an
 d analysis conducted using rapid qualitative analytic approaches and them
 atic analysis. In this talk\, we will present the work in progress\, incl
 uding study participants\, intervention delivery updates\, major facilita
 tors and barriers to implementation\, and lessons learned.\n\nSpeaker:\nA
 rchana Shrestha\n\nAdmission:\nFree\n\nFood:\nLunch: Boxed lunch will be 
 served prior at 11:50 am for those who RSVP'd by 02/03/2026\n\nDetails UR
 L:\nhttps://medicine.yale.edu/event/cmips-seminar-archana-shrestha/\n
DTEND;TZID=America/New_York:20260206T130000
DTSTAMP:20260421T104252Z
DTSTART;TZID=America/New_York:20260206T120000
LOCATION:URL: https://yale.zoom.us/j/98782597992?from=addon
SEQUENCE:0
STATUS:Confirmed
SUMMARY:CMIPS Seminar: Archana Shrestha "Community Health Worker-led Hyper
 tension Control Implementation Trial in Nepal: Work in Progress"
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