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DTSTART:20241103T020000
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DESCRIPTION:Largely considered a neglected tropical disease confined to La
 tin America\, Trypanosoma cruzi infection – Chagas disease – is increasin
 gly recognized as a public and veterinary health concern across the south
 ern United States. The protozoan parasite infects humans\, dogs and a wid
 e range of domestic and wild mammals\, where transmission is driven by tr
 iatomine (‘kissing bug’) insect vectors that shed the protozoan through t
 heir feces. A subset of infected individuals develops Chagas disease\, of
 ten characterized by cardiomyopathy and sometimes fatal outcomes. The bro
 ad host range of both the triatomines and the parasite creates ecological
  complexity that challenges effective control. Our research team establis
 hed the Kissing Bug Community Science program over 10 years ago\, resulti
 ng in over 10\,000 triatomine submissions across 27 southern U.S. states 
 and 5 countries. More than half of the insects are infected with T . cruz
 i \, and blood meal analysis reveals dogs as the most common hosts\, foll
 owed by a diversity of wildlife\, domestic animals and humans. Major chal
 lenges remain in the surveillance and management of Chagas disease\, incl
 uding imperfect diagnostics\, limited treatment options\, and widespread\
 , highly-infected vectors with few viable control strategies. Our team is
  advancing diagnostic tools and conducting antiparasitic treatment trials
  in naturally-infected dogs\, with translational potential for human heal
 th. We are also piloting the use of systemic insecticides\, demonstrating
  high mortality of triatomines that feed on treated dogs and chickens\, a
 s we work toward community-level interventions to reduce vector populatio
 ns. Ongoing insectary trials of triatomine feeding and defecation behavio
 rs provide a biological basis for patterns observed in the field. Our col
 laborative studies across Texas\, Mexico and Guatemala highlight differen
 t epidemiological and ecological settings that shape Chagas disease risk.
  The growing recognition of endemic transmission in the United States und
 erscores the need for a ‘One Health’ approach to protect humans and anima
 ls throughout the Americas. YSPH values inclusion and access for all part
 icipants If you have questions about accessibility or would like to reque
 st an accommodation\, please contact Christina Ciarleglio at christina.ci
 arleglio@yale.edu\n\nSpeaker:\nSarah A. Hamer\, MS\, PhD\, DVM\, DACVPM \
 n\nAdmission:\nFree\n\nDetails URL:\nhttps://medicine.yale.edu/event/emd-
 seminar-series-tba-10/\n
DTEND;TZID=America/New_York:20251029T130000
DTSTAMP:20260926T194704Z
DTSTART;TZID=America/New_York:20251029T120000
GEO:41.303666;-72.932218
LOCATION:Yale School of Public Health (LEPH)\, Winslow\, 60 College Street
 \, New Haven\, CT\, United States
SEQUENCE:0
STATUS:Confirmed
SUMMARY:EMD Seminar Series Brandon Brei Memorial Lecture: Sarah Hamer - "E
 co-epidemiology of Chagas disease across the Americas"
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