2025
Paternal and maternal exposures to per- and polyfluoroalkyl substances (PFAS) and birth outcomes: a multi-country cohort study
Guo P, Luo J, Zhang J, Bonde J, Struciński P, Ohniev V, Arah O, Deziel N, Warren J, Toft G, Liew Z. Paternal and maternal exposures to per- and polyfluoroalkyl substances (PFAS) and birth outcomes: a multi-country cohort study. Environmental Health 2025, 24: 48. PMID: 40652244, PMCID: PMC12255010, DOI: 10.1186/s12940-025-01199-y.Peer-Reviewed Original ResearchConceptsShort birth lengthAdverse birth outcomesBirth outcomesBirth lengthMulti-country cohort studyAntenatal care visitsAssociated with lower offspring birth weightParent-specific effectsPFAS exposureMaternal exposureBirth weightQuantile g-computationOffspring birth weightPrenatal PFAS exposureCare visitsResultsNo associationEffects of PFAS exposureG-computationLow birth weightCohort studyINUENDO cohortEffect sizeMedical recordsMethodsThis studyPaternal exposure
2023
Investigation of Sources of Fluorinated Compounds in Private Water Supplies in an Oil and Gas-Producing Region of Northern West Virginia
Siegel H, Nason S, Warren J, Prunas O, Deziel N, Saiers J. Investigation of Sources of Fluorinated Compounds in Private Water Supplies in an Oil and Gas-Producing Region of Northern West Virginia. Environmental Science And Technology 2023, 57: 17452-17464. PMID: 37923386, PMCID: PMC10653085, DOI: 10.1021/acs.est.3c05192.Peer-Reviewed Original ResearchMeSH KeywordsAlkanesulfonic AcidsBayes TheoremDrinking WaterFluorocarbonsGroundwaterWater Pollutants, ChemicalWater SupplyWest VirginiaConceptsNorthern West VirginiaMaximum contaminant levelWater supplySurface water concentrationsNearby point sourcesSurface water samplesGas-producing regionsSurface water sourcesPFAS concentrationsPoint sourcesPrivate wellsPublic water supplyGeochemical controlsGroundwater chemistryRecharge zoneWest VirginiaWater wellsInvestigation of sourcesModel resultsPrivate water suppliesPFAS sourcesTopographic characteristicsPFAS transportWater receptorPolyfluoroalkyl substancesPer- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study
Rosen Vollmar A, Lin E, Nason S, Santiago K, Johnson C, Ma X, Godri Pollitt K, Deziel N. Per- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study. Journal Of Exposure Science & Environmental Epidemiology 2023, 33: 737-747. PMID: 37730931, PMCID: PMC10541328, DOI: 10.1038/s41370-023-00603-4.Peer-Reviewed Original ResearchMeSH KeywordsAlkanesulfonic AcidsChildEnvironmental ExposureEnvironmental PollutantsFluorocarbonsHumansInfant, NewbornPilot ProjectsThyroid HormonesConceptsThyroid hormone concentrationsNeonatal characteristicsThyroid hormone measurementsHormone concentrationsThyroid hormonesBlood spotsPilot studyNewborn DBSHormone measurementsPopulation-based studyThyroid hormone levelsEnvironmental risk factorsPFAS concentrationsNewborn screening testNon-parametric WilcoxonThyroid diseaseRisk factorsHormone levelsKruskal-Wallis testPFAS exposureThyroid hormone dataScreening testNeonatal DBSEnvironmental exposuresPerformance liquid chromatography-mass spectrometry
2022
Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort
Luo J, Ramlau-Hansen CH, Kesmodel US, Xiao J, Vasiliou V, Deziel NC, Zhang Y, Olsen J, Liew Z. Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort. Environmental Health Perspectives 2022, 130: 017006. PMID: 35080464, PMCID: PMC8791068, DOI: 10.1289/ehp9478.Peer-Reviewed Original ResearchConceptsDanish National Birth CohortMaternal alcohol intakePrenatal PFAS exposurePalpebral fissure lengthShorter palpebral fissure lengthNational Birth CohortYears of agePFAS exposureSecond tertileAlcohol intakePrenatal exposureOdds ratioBirth cohortSpecific neurologic deficitsConfidence intervalsFetal brain developmentSex-specific associationsNeurologic deficitsFirst trimesterPotential confoundersNeurodevelopmental effectsAlcohol exposureStratified analysisNormal groupMultinomial logistic regression
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