2025
Paternal and Maternal Exposures to Per- and Polyfluoroalkyl Substances and Child Behavioral Difficulties: A Parental Comparison Study
Guo P, Luo J, Zhang J, Bonde J, Struciński P, Ohniev V, Arah O, Deziel N, Warren J, Toft G, Liew Z. Paternal and Maternal Exposures to Per- and Polyfluoroalkyl Substances and Child Behavioral Difficulties: A Parental Comparison Study. Environmental Science And Technology 2025, 59: 5973-5982. PMID: 40104843, DOI: 10.1021/acs.est.4c13040.Peer-Reviewed Original ResearchConceptsBehavioral difficultiesAssociated with internalizing difficultiesStrengths and Difficulties QuestionnaireChildren's behavioral difficultiesSex-specific mannerSex-specific cut-offsExternalizing difficultiesMaternal PFASWeeks of gestationParent-rated Strengths and Difficulties QuestionnairePrenatal PFAS exposurePaternal exposurePolyfluoroalkyl substancesDifficulties QuestionnaireChild sexOffspring neurodevelopmentAssociated with behavioral difficultiesPrenatal exposureAntenatal clinicMaternal prenatal exposureINUENDO cohortAged 5Maternal exposurePerfluorononanoic acidDevelopmental toxicity
2016
A systematic evaluation of chemicals in hydraulic-fracturing fluids and wastewater for reproductive and developmental toxicity
Elliott EG, Ettinger AS, Leaderer BP, Bracken MB, Deziel NC. A systematic evaluation of chemicals in hydraulic-fracturing fluids and wastewater for reproductive and developmental toxicity. Journal Of Exposure Science & Environmental Epidemiology 2016, 27: 90-99. PMID: 26732376, DOI: 10.1038/jes.2015.81.Peer-Reviewed Original ResearchConceptsWater quality standardsFederal water quality standardsQuality standardsHuman health impactsNatural gas developmentEnvironmental concentrationsHundreds of substancesDevelopmental toxicityReprotox databasesHuman exposureToxicity informationGas developmentExposure assessmentIncorporation of dataHealth StudyHealth impactsSystematic screening approachHydraulic-fracturing fluidsChemical Abstract Service Registry NumbersCandidate analytesChemicalsDrinking waterLikely etiologic agentWastewaterUnconventional oil
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