2025
Short-term estradiol administration does not restore endothelin‐B receptor‐mediated vasodilation in postmenopausal women
Nuckols V, Shoemaker L, Kuczmarski A, Haigh K, McGinty S, Del Vecchio A, Schwab A, Edwards D, Taylor H, Wenner M. Short-term estradiol administration does not restore endothelin‐B receptor‐mediated vasodilation in postmenopausal women. AJP Heart And Circulatory Physiology 2025, 328: h327-h332. PMID: 39773019, PMCID: PMC12175985, DOI: 10.1152/ajpheart.00815.2024.Peer-Reviewed Original ResearchConceptsPostmenopausal womenExogenous estradiol administrationEndothelin B receptorEstradiol administrationPremenopausal womenLactated RingeHealthy postmenopausal womenYoung womenLaser Doppler flowmetryEndothelin-BVasodilatory responseTransdermal patchDoppler flowmetryCutaneous microcirculationVasodilationEstradiolAdministrationWomenReceptorsRingerBlockadeFlowmetry
2016
Effects of hormones on skin wrinkles and rigidity vary by race/ethnicity: four-year follow-up from the ancillary skin study of the Kronos Early Estrogen Prevention Study
Owen CM, Pal L, Mumford SL, Freeman R, Isaac B, McDonald L, Santoro N, Taylor HS, Wolff EF. Effects of hormones on skin wrinkles and rigidity vary by race/ethnicity: four-year follow-up from the ancillary skin study of the Kronos Early Estrogen Prevention Study. Fertility And Sterility 2016, 106: 1170-1175.e3. PMID: 27393520, DOI: 10.1016/j.fertnstert.2016.06.023.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, CutaneousAdministration, OralAdultBlack or African AmericanDouble-Blind MethodDrug CombinationsElasticityEstradiolEstrogen Replacement TherapyEstrogens, Conjugated (USP)FemaleHumansMenopauseMiddle AgedProgesteroneSkinSkin AgingTime FactorsTransdermal PatchTreatment OutcomeUnited StatesWhite PeopleConceptsKronos Early Estrogen Prevention StudyConjugated equine estrogensHormone therapyRace/ethnicityRigidity scoresSkin wrinklesPrevention StudyOral conjugated equine estrogenWhite womenLowest wrinkle scoresPlacebo-controlled trialLast menstrual periodAcademic medical centerBlack womenWrinkle scoreEffects of hormonesEquine estrogensMenopausal womenMenstrual periodMedical CenterMAIN OUTCOMESkin rigidityWomenPlaceboScores
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