2025
Use of AMD3100 for Bone Marrow Derived Mesenchymal Stem Cells Mobilization in the Treatment of Murine Asherman’s Syndrome
Flores V, Delis P, Mamillapalli R, Taylor H. Use of AMD3100 for Bone Marrow Derived Mesenchymal Stem Cells Mobilization in the Treatment of Murine Asherman’s Syndrome. F&S Science 2025 PMID: 40818715, DOI: 10.1016/j.xfss.2025.08.003.Peer-Reviewed Original ResearchAsherman's syndromePreterm ruptureAS inductionMurine modelProgenitor cellsMesenchymal stem cell mobilizationMice treated with AMD3100Preterm rupture of membranesAMD3100-treated miceRupture of membranesOptimal timingStem cell mobilizationBone marrow transplantationTreatment groupsLevels of CXCL12Source of progenitor cellsRecurrent pregnancy lossEndometrial progenitor cellsBMD-MSCsLikelihood of pregnancyHysteroscopic adhesiolysisPlacental abruptionUterine repairSevere ASMarrow transplantation
2022
Chemokine C-X-C receptor 4 mediates recruitment of bone marrow-derived nonhematopoietic and immune cells to the pregnant uterus
Fang YY, Lyu F, Abuwala N, Tal A, Chen AY, Taylor HS, Tal R. Chemokine C-X-C receptor 4 mediates recruitment of bone marrow-derived nonhematopoietic and immune cells to the pregnant uterus. Biology Of Reproduction 2022, 106: 1083-1097. PMID: 35134114, PMCID: PMC9198949, DOI: 10.1093/biolre/ioac029.Peer-Reviewed Original ResearchConceptsBone marrow-derived progenitor cellsBM-derived cellsPregnant deciduaPregnant uterusMarrow-derived progenitor cellsC receptor 4Pregnancy-induced increaseRecruitment of boneProgenitor cellsWild-type C57BL/6CXCL12-CXCR4 axisStem/progenitor cellsTamoxifen-inducible CreNK cellsControl miceBM donorsCXCR4 expressionTransgenic GFP miceImmune cellsReceptor 4Nonpregnant uterusChemokine CCXCL12 ligandFemale recipientsSuccessful implantation
2021
Characterization of Bone Marrow Progenitor Cell Uterine Engraftment and Transdifferentiation
Mamillapalli R, Mutlu L, Taylor HS. Characterization of Bone Marrow Progenitor Cell Uterine Engraftment and Transdifferentiation. Reproductive Sciences 2021, 29: 2382-2390. PMID: 34515983, DOI: 10.1007/s43032-021-00738-5.Peer-Reviewed Original ResearchConceptsBone marrow-derived stem cellsRecipient miceBone marrow-derived cellsProgenitor cellsBone marrow transplantMarrow-derived cellsMarrow-derived stem cellsSpecific uterine cell typesBone marrow-derived progenitorsMarrow-derived progenitorsUterine cell typesUpregulation of markersCell surface markersStem cellsSpecific stem cell markersStem cell markersCell typesUterine repairMarrow transplantStem cell componentUterine tissueMurine modelMaintenance of fertilityDifferentiation of BMSCsCell markersBone Marrow-Derived Progenitor Cells Contribute to Remodeling of the Postpartum Uterus
Tal R, Kisa J, Abuwala N, Kliman HJ, Shaikh S, Chen AY, Lyu F, Taylor HS. Bone Marrow-Derived Progenitor Cells Contribute to Remodeling of the Postpartum Uterus. Stem Cells 2021, 39: 1489-1505. PMID: 34224633, PMCID: PMC9313624, DOI: 10.1002/stem.3431.Peer-Reviewed Original ResearchConceptsPostpartum uterusEndometrial stem/progenitor cellsBone marrow-derived progenitor cellsMarrow-derived progenitor cellsF4/80 macrophage markerUterine tissue regenerationProgenitor cellsC57BL/6J female micePostpartum day 1Cytokeratin-positive epithelial cellsBlood vessel endotheliumStem/progenitor cellsPrepregnancy levelsBM transplantsEndometrial regenerationEndometrial cellsFemale miceMacrophage markersPan-leukocytesLuminal epitheliumBone marrowDay 1BMDCsUterine cellsVessel endothelium
2019
Bone-marrow-derived endothelial progenitor cells contribute to vasculogenesis of pregnant mouse uterus
Tal R, Dong D, Shaikh S, Mamillapalli R, Taylor HS. Bone-marrow-derived endothelial progenitor cells contribute to vasculogenesis of pregnant mouse uterus. Biology Of Reproduction 2019, 100: 1228-1237. PMID: 30601943, PMCID: PMC6497522, DOI: 10.1093/biolre/ioy265.Peer-Reviewed Original ResearchConceptsEndothelial progenitor cellsPregnant uterusImplantation sitesPregnant miceBM-derived endothelial progenitor cellsProgenitor cellsEarly pregnant uterusUterine implantation sitesContribution of BMNew blood vesselsEndometrial growthBM transplantationEndothelial cell populationEndometrial vasculaturePregnancy maintenanceDecidual vasculatureMouse recipientsGestational dayVascular endotheliumEndothelial-specific promoterBone marrowTransgenic miceMouse deciduaFlow cytometryMice
2014
Identification of Putative Fallopian Tube Stem Cells
Snegovskikh V, Mutlu L, Massasa E, Taylor HS. Identification of Putative Fallopian Tube Stem Cells. Reproductive Sciences 2014, 21: 1460-1464. PMID: 25305130, PMCID: PMC4231131, DOI: 10.1177/1933719114553448.Peer-Reviewed Original ResearchConceptsLabel-retaining cellsStem cellsStem/progenitor cell populationsStem cell nicheProgenitor cell populationsDAPI-stained nucleiStem cell reservePutative stem cellsCell nicheMultiple tissuesProgenitor cellsConfocal microscopyCell populationsImmunofluorescence studiesReproductive tractSection tissueCellsTissue regenerationOviductCell reserveTissueRegenerationNichePopulationNucleus
2008
Stem Cells and the Pathogenesis of Endometriosis
Sasson IE, Taylor HS. Stem Cells and the Pathogenesis of Endometriosis. Annals Of The New York Academy Of Sciences 2008, 1127: 106-115. PMID: 18443337, PMCID: PMC3107843, DOI: 10.1196/annals.1434.014.Peer-Reviewed Original ResearchConceptsPathogenesis of endometriosisGynecological disordersEndometrial stem/progenitor cellsChronic pelvic painCommon gynecological disorderEndometrial stem cellsStem/progenitor cellsStem cellsPelvic painEndometrial tissueUterine cavityLikely multifactorialExtensive morbidityMenstrual cycleEndometriosisRole of geneticsImmune systemNarrative reviewPathogenesisProgenitor cellsPotential roleImportant unanswered questionsSuch cellsDisordersCells
2007
Demonstration of Multipotent Stem Cells in the Adult Human Endometrium by In Vitro Chondrogenesis
Wolff EF, Wolff AB, Du H, Taylor HS. Demonstration of Multipotent Stem Cells in the Adult Human Endometrium by In Vitro Chondrogenesis. Reproductive Sciences 2007, 14: 524-533. PMID: 17959881, DOI: 10.1177/1933719107306896.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsMultipotent stem cellsFallopian tubeType II collagenStem cellsReproductive-aged womenHuman articular cartilageEndometrial stem cellsAdult human endometriumII collagenMultilineage differentiationArticular cartilageBenign diseaseEndometrial tissueExtramedullary tissuesHuman endometriumCell pelletsEndometriumChondrogenic mediumStromal cellsLigament cellsSulfated glycosaminoglycansGrowth factorProgenitor cellsCell types
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply