2025
Stem cells and female reproduction: endometrial physiology, disease and therapy
Cevik E, Mamillapalli R, Taylor H. Stem cells and female reproduction: endometrial physiology, disease and therapy. Stem Cells 2025, 43: sxaf016. PMID: 40317260, DOI: 10.1093/stmcls/sxaf016.Peer-Reviewed Original ResearchConceptsBone marrow-derived mesenchymal stem cellsStem cellsKnowledge of stem cell biologyStem cell-based therapiesEngraftment of stem cellsRecurrent pregnancy lossImprove pregnancy outcomesEndometrial progenitor cellsMinimally invasive techniquesProgenitor stem cellsCell-based therapiesStem cell biologyAsherman's syndromeCells to areasPotential therapeutic avenuePregnancy outcomesThin endometriumHuman endometriumMarrow-derived mesenchymal stem cellsTargeted therapyEndometrial repairEndometrial regenerationPregnancy lossImplant failureInvasive techniques
2017
CXCL12 Promotes Stem Cell Recruitment and Uterine Repair after Injury in Asherman’s Syndrome
Ersoy G, Zolbin MM, Cosar E, Moridi I, Mamillapalli R, Taylor HS. CXCL12 Promotes Stem Cell Recruitment and Uterine Repair after Injury in Asherman’s Syndrome. Molecular Therapy — Methods & Clinical Development 2017, 4: 169-177. PMID: 28345002, PMCID: PMC5363300, DOI: 10.1016/j.omtm.2017.01.001.Peer-Reviewed Original ResearchAsherman's syndromeUterine repairBone marrow-derived mesenchymal stem cellsStem cell recruitmentCell recruitmentStem cell supplementationAdverse pregnancy outcomesTreatment of infertilityMarrow-derived mesenchymal stem cellsStem cell engraftmentCXCL12 administrationUterine fibrosisPregnancy outcomesUterine disordersUterine injuryReceptor antagonistReceptor agonistFunctional improvementMurine modelCXCL12 treatmentCell engraftmentLitter sizeCXCL12 productionMesenchymal stem cellsSyndrome
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