2025
The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy
Mamillapalli R, Gawde N, Fay M, Atwani R, Moridi I, Taylor H. The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy. Reproductive Biology And Endocrinology 2025, 23: 83. PMID: 40457415, PMCID: PMC12128536, DOI: 10.1186/s12958-025-01420-0.Peer-Reviewed Original ResearchConceptsHOXA11-ASHOXA11-AS expressionEutopic endometriumLong non-coding RNAsEctopic endometriotic lesionsEndometriotic cell linesInvasion of endometriosisEndometrial stromal cellsReal-time polymerase chain reactionNon-coding RNAsEndometriotic lesionsEndometriosis therapyEndometriosis patientsNormal endometriumProgestin responsivenessEndometrial developmentTreatment responsePolymerase chain reactionQuantitative real-time polymerase chain reactionEndometriosisEndometriosis treatmentMethodsTissue samplesStromal cellsPotential target genesEndometrium
2022
ASSESSMENT OF PATIENT-REPORTED PAIN RELIEF IN TREATED ENDOMETRIOSIS PATIENTS: FINDINGS FROM A REAL-WORLD STUDY IN THE UNITED STATES
Surrey E, Xu Y, Frakes E, Scott M, Lee L, Piercy J, Taylor H. ASSESSMENT OF PATIENT-REPORTED PAIN RELIEF IN TREATED ENDOMETRIOSIS PATIENTS: FINDINGS FROM A REAL-WORLD STUDY IN THE UNITED STATES. Fertility And Sterility 2022, 118: e223-e224. DOI: 10.1016/j.fertnstert.2022.08.634.Peer-Reviewed Original Research
2021
Endometriosis stromal cells induce bone marrow mesenchymal stem cell differentiation and PD-1 expression through paracrine signaling
Chen P, Mamillapalli R, Habata S, Taylor HS. Endometriosis stromal cells induce bone marrow mesenchymal stem cell differentiation and PD-1 expression through paracrine signaling. Molecular And Cellular Biochemistry 2021, 476: 1717-1727. PMID: 33428059, DOI: 10.1007/s11010-020-04012-1.Peer-Reviewed Original ResearchConceptsPD-1 expressionPD-1Stromal cellsT-cell PD-1 expressionEndometriosis stromal cellsGrowth of endometriosisPD-1 inductionDifferentiation of BMDCsBone marrow mesenchymal stem cell differentiationT cell quiescenceBMDC differentiationImmune toleranceEndometriosis patientsEndometriotic lesionsNormal endometriumEndometrial cellsEndometriosis cellsGynecological disordersImmune surveillanceMurine modelBMDCsEndometriosisLesion sizeCXCR4 receptorLesions
2019
Patterns of Prescription Opioid Use in Women With Endometriosis
Lamvu G, Soliman AM, Manthena SR, Gordon K, Knight J, Taylor HS. Patterns of Prescription Opioid Use in Women With Endometriosis. Obstetrics And Gynecology 2019, 133: 1120-1130. PMID: 31135725, PMCID: PMC6553518, DOI: 10.1097/aog.0000000000003267.Peer-Reviewed Original ResearchConceptsOpioid prescriptionsControl groupBenzodiazepine prescriptionsOpioid useEndometriosis patientsCase groupClinformatics DataMart databaseFirst opioid prescriptionMultiple opioid prescriptionsOpioid Prescribing PatternsPrescription opioid useMultivariable regression analysisRelative risk ratiosConcomitant opioidsPrescribing patternsDaily doseMean ageRisk ratioConcomitant useDays' supplyRetrospective analysisInsurance payerΧ statisticEndometriosisPatientsImpact of Elagolix on Quality of Life Among Endometriosis Patients: A Pooled Analysis of 2 Phase III Clinical Trials [13J]
Taylor H, Soliman A, Palac H, Surrey E. Impact of Elagolix on Quality of Life Among Endometriosis Patients: A Pooled Analysis of 2 Phase III Clinical Trials [13J]. Obstetrics And Gynecology 2019, 133: 110-110. DOI: 10.1097/01.aog.0000558829.95268.69.Peer-Reviewed Original ResearchSevere painMonth 3Scale scoreGonadotrophin-releasing hormone antagonistSevere endometriosis-associated painPhase III clinical trialsEndometriosis Health ProfileEndometriosis-associated painPhase III randomizedPlacebo-controlled trialEndometriosis-associated symptomsHealth-related qualityDose-dependent fashionQuality of lifePremenopausal womenHRQL questionnairesMonth 6EHP-30Endometriosis patientsPooled analysisClinical trialsMonths 1Health profileBaseline scoresElagolix
2017
Predictive Biomarkers May allow Precision Therapy of Endometriosis
Hou Z, Mamillapalli R, Taylor HS. Predictive Biomarkers May allow Precision Therapy of Endometriosis. Journal Of Endometriosis And Pelvic Pain Disorders 2017, 9: 279-285. PMID: 35441077, PMCID: PMC9014966, DOI: 10.5301/jeppd.5000311.Peer-Reviewed Original ResearchMedroxyprogesterone acetatePredictive biomarkersProgesterone receptorEstrogen receptorPrecision therapyEutopic endometrial stromal cellsSelective estrogen receptor modulatorsEffect of bazedoxifeneEndometrial stromal cellsEstrogen receptor modulatorsPathogenesis of endometriosisPrimary eutopic endometrial stromal cellsCommon molecular targetsPRA/BPersonalized medicine approachReverse transcriptase-polymerase chain reaction analysisTranscriptase-polymerase chain reaction analysisBaseline expression levelsPelvic painEndometrial biopsyEndometriosis therapySevere endometriosisProgestin resistanceEndometriosis patientsPR expressionIncremental direct and indirect cost burden attributed to endometriosis surgeries in the United States
Soliman AM, Taylor H, Bonafede M, Nelson JK, Castelli-Haley J. Incremental direct and indirect cost burden attributed to endometriosis surgeries in the United States. Fertility And Sterility 2017, 107: 1181-1190.e2. PMID: 28476181, DOI: 10.1016/j.fertnstert.2017.03.020.Peer-Reviewed Original ResearchConceptsPost-index periodEndometriosis patientsSurgery cohortIndirect costsDirect costsHigher healthcare resource utilizationTruven Health MarketScan CommercialIndirect cost burdenProductivity Management databasesRetrospective cohort studyHealthcare resource utilizationAnnual indirect costsShort-term disabilityAnnual direct costsTotal healthcare expendituresHigher direct costsTotal indirect costsEndometriosis surgeryIndex surgeryCohort studyMarketScan CommercialPrimary outcomeSurgery typeHealthcare utilizationMAIN OUTCOME
2016
Sexual function in endometriosis patients and their partners: effect of the disease and consequences of treatment
Pluchino N, Wenger JM, Petignat P, Tal R, Bolmont M, Taylor HS, Bianchi-Demicheli F. Sexual function in endometriosis patients and their partners: effect of the disease and consequences of treatment. Human Reproduction Update 2016, 22: 762-774. PMID: 27591248, DOI: 10.1093/humupd/dmw031.Peer-Reviewed Original ResearchConceptsSexual functionEndometriosis patientsPresence of dyspareuniaChronic pelvic painPresence of endometriosisEffect of surgeryOverall sexual functionEffect of endometriosisHalf of womenConsequence of treatmentQuality of lifeSystematic literature searchHealth care interventionsPelvic painDeep dyspareuniaSurgical treatmentMental comorbiditiesGynecologic disordersSexual painHormonal factorsHormonal treatmentMedical conditionsEndometriosisCoital painAdvanced stage
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