2024
TET3-overexpressing macrophages promote endometriosis
Lv H, Liu B, Dai Y, Li F, Bellone S, Zhou Y, Mamillapalli R, Zhao D, Venkatachalapathy M, Hu Y, Carmichael G, Li D, Taylor H, Huang Y. TET3-overexpressing macrophages promote endometriosis. Journal Of Clinical Investigation 2024, 134: e181839. PMID: 39141428, PMCID: PMC11527447, DOI: 10.1172/jci181839.Peer-Reviewed Original ResearchDisease-associated macrophagesTET3 overexpressionHuman endometriosis lesionsPathophysiology of endometriosisPro-inflammatory cytokine productionChronic inflammatory diseaseReproductive age womenEndometriosis lesionsE3 ubiquitin ligasePathogenic macrophagesCytokine productionEndometriosisInflammatory diseasesTET3 knockdownEndometriosis progressionPathogenic contributorsLet-7 miRNA expressionAge womenMacrophagesMouse macrophagesTherapeutic targetUbiquitin ligaseTET3MiceDisease
2020
Accurate Diagnosis of Endometriosis Using Serum MicroRNAs
Moustafa S, Burn M, Mamillapalli R, Nematian S, Flores V, Taylor H. Accurate Diagnosis of Endometriosis Using Serum MicroRNAs. Obstetrical & Gynecological Survey 2020, 75: 404-406. DOI: 10.1097/ogx.0000000000000816.Peer-Reviewed Original Research
2019
Endometriosis
Flores V, Taylor H. Endometriosis. DeckerMed Family Medicine 2019 DOI: 10.2310/fm.1005.Peer-Reviewed Original ResearchPelvic painSurgical therapyGrowth of endometriosisReproductive-age womenRole of estrogenDiagnosis of endometriosisGynecologic diseaseRetrograde menstruationCommon symptomsEndometriosis managementTreatment optionsPatient preferencesAge womenEndometriosisMolecular pathwaysPainPatientsAberrant gene expressionInfertilityTherapyDiseaseGene expressionDyspareuniaEstrogenEtiologyEndometriosis
Flores V, Taylor H. Endometriosis. DeckerMed Medicine 2019 DOI: 10.2310/im.1005.Peer-Reviewed Original ResearchPelvic painSurgical therapyGrowth of endometriosisReproductive-age womenRole of estrogenDiagnosis of endometriosisGynecologic diseaseRetrograde menstruationCommon symptomsEndometriosis managementTreatment optionsPatient preferencesAge womenEndometriosisMolecular pathwaysPainPatientsAberrant gene expressionInfertilityTherapyDiseaseGene expressionDyspareuniaEstrogenEtiologyLack of an Association between a Polymorphism in the KRAS 3′ Untranslated Region (rs61764370) and Endometriosis in a Large European Case-Control Study
D'Hooghe TM, Grechukhina O, Cho S, Fassbender A, O D, Peterse D, Weidhaas J, Taylor HS. Lack of an Association between a Polymorphism in the KRAS 3′ Untranslated Region (rs61764370) and Endometriosis in a Large European Case-Control Study. Gynecologic And Obstetric Investigation 2019, 84: 575-582. PMID: 31185482, DOI: 10.1159/000500626.Peer-Reviewed Original ResearchConceptsCase-control studyGerm-line single nucleotide polymorphismsKRAS geneLarge case-control studyReproductive-age womenType of infertilityBody mass indexEuropean case-control studyKRAS 3' untranslated regionLarge European case-control studyMicroRNA-binding sitesMedical therapyPeritoneal biopsiesMass indexPeripheral bloodAge womenPolymerase chain reactionCommon disorderTreatment resistanceEndometriosisCarrier rateVariant allelesCaucasian populationGene variantsKRAS allele
2009
Inflammation in Reproductive Disorders
Weiss G, Goldsmith LT, Taylor RN, Bellet D, Taylor HS. Inflammation in Reproductive Disorders. Reproductive Sciences 2009, 16: 216-229. PMID: 19208790, PMCID: PMC3107847, DOI: 10.1177/1933719108330087.Peer-Reviewed Original ResearchConceptsInflammatory disordersImmune responseReproductive-age womenNonspecific immune responsesImmune cell traffickingAnatomic disordersEndometrial developmentEndometrial functionEndometrial receptivityGynecologic diseaseInflammatory cytokinesAge womenImmune cellsMenstrual cycleInflammationTargeted treatmentReproductive disordersHormone productionCell traffickingInfectious diseasesNormal tissuesReproductive medicineDisordersTissue repairDisease
2006
Ovarian cryopreservation with transposition of a contralateral ovary: a combined approach for fertility preservation in women receiving pelvic radiation
Martin JR, Kodaman P, Oktay K, Taylor HS. Ovarian cryopreservation with transposition of a contralateral ovary: a combined approach for fertility preservation in women receiving pelvic radiation. Fertility And Sterility 2006, 87: 189.e5-189.e7. PMID: 17084399, DOI: 10.1016/j.fertnstert.2006.04.051.Peer-Reviewed Original ResearchConceptsReproductive-age womenPelvic radiationFertility preservationOvarian transpositionOvarian cryopreservationContralateral ovaryAge womenFuture fertility optionsLaparoscopic ovarian transpositionTertiary care hospitalSpinal cord tumorsNulligravid womenPelvic irradiationCare hospitalCord tumorsCase reportIVF centerLaparoscopic surgeryFertility optionsMAIN OUTCOMESingle ovaryWomenOvariesCryopreservationTransposition
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