2025
Stem cells and female reproduction: endometrial physiology, disease and therapy
Cevik E, Mamillapalli R, Taylor H. Stem cells and female reproduction: endometrial physiology, disease and therapy. Stem Cells 2025, 43: sxaf016. PMID: 40317260, DOI: 10.1093/stmcls/sxaf016.Peer-Reviewed Original ResearchConceptsBone marrow-derived mesenchymal stem cellsStem cellsKnowledge of stem cell biologyStem cell-based therapiesEngraftment of stem cellsRecurrent pregnancy lossImprove pregnancy outcomesEndometrial progenitor cellsMinimally invasive techniquesProgenitor stem cellsCell-based therapiesStem cell biologyAsherman's syndromeCells to areasPotential therapeutic avenuePregnancy outcomesThin endometriumHuman endometriumMarrow-derived mesenchymal stem cellsTargeted therapyEndometrial repairEndometrial regenerationPregnancy lossImplant failureInvasive techniques
2018
Bone marrow-derived cells or C-X-C motif chemokine 12 (CXCL12) treatment improve thin endometrium in a mouse model
Yi KW, Mamillapalli R, Sahin C, Song J, Tal R, Taylor HS. Bone marrow-derived cells or C-X-C motif chemokine 12 (CXCL12) treatment improve thin endometrium in a mouse model. Biology Of Reproduction 2018, 100: 61-70. PMID: 30084961, PMCID: PMC6335209, DOI: 10.1093/biolre/ioy175.Peer-Reviewed Original ResearchConceptsBone marrow-derived cellsMarrow-derived cellsThin endometriumEndometrial regenerationComparable efficacyTherapeutic effectC motif chemokine 12Potential therapeutic effectsMatrix metalloproteinase-2MRNA expression levelsLeukemia inhibitory factorIntegrin beta 3Endometrial growthEndometrial receptivityCD31 immunoreactivityInterleukin-1βPregnancy rateKi-67Mouse modelEpithelial areaSuccessful implantationMetalloproteinase-2EndometriumCXCL12Inhibitory factor
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