2025
Stem cells and female reproduction: endometrial physiology, disease and therapy
Cevik E, Mamillapalli R, Taylor H. Stem cells and female reproduction: endometrial physiology, disease and therapy. Stem Cells 2025, 43: sxaf016. PMID: 40317260, DOI: 10.1093/stmcls/sxaf016.Peer-Reviewed Original ResearchConceptsBone marrow-derived mesenchymal stem cellsStem cellsKnowledge of stem cell biologyStem cell-based therapiesEngraftment of stem cellsRecurrent pregnancy lossImprove pregnancy outcomesEndometrial progenitor cellsMinimally invasive techniquesProgenitor stem cellsCell-based therapiesStem cell biologyAsherman's syndromeCells to areasPotential therapeutic avenuePregnancy outcomesThin endometriumHuman endometriumMarrow-derived mesenchymal stem cellsTargeted therapyEndometrial repairEndometrial regenerationPregnancy lossImplant failureInvasive techniques
2017
Systemic administration of bone marrow‐derived cells leads to better uterine engraftment than use of uterine‐derived cells or local injection
Liu Y, Tal R, Pluchino N, Mamillapalli R, Taylor HS. Systemic administration of bone marrow‐derived cells leads to better uterine engraftment than use of uterine‐derived cells or local injection. Journal Of Cellular And Molecular Medicine 2017, 22: 67-76. PMID: 28782281, PMCID: PMC5742714, DOI: 10.1111/jcmm.13294.Peer-Reviewed Original ResearchConceptsBM-derived cellsSystemic administrationFluorescence-activated cell sortingLocal injectionBone marrow-derived cellsSingle uterine hornMarrow-derived cellsWild-type recipientsStem cell engraftmentStem cell-based therapiesAsherman's syndromeCell-based therapiesIntrauterine injectionUterine injuryEndometrial cellsSystemic injectionLocal injuryImmunohistochemical stainingUterine tissuePotential therapyCell recruitmentSystemic routeAdministration resultsUterine hornCell engraftment
2010
Implantation failure: molecular mechanisms and clinical treatment
Cakmak H, Taylor HS. Implantation failure: molecular mechanisms and clinical treatment. Human Reproduction Update 2010, 17: 242-253. PMID: 20729534, PMCID: PMC3039220, DOI: 10.1093/humupd/dmq037.Peer-Reviewed Original ResearchConceptsGynecological diseasesEndometrial receptivityImplantation rateImplantation failureOptimal current therapyPolycystic ovarian syndromeStem cell-based therapiesSynchronized dialogueOvarian syndromePregnancy outcomesCell-based therapiesImplantation markersSuccessful pregnancySurgical interventionCurrent therapiesEndometrial cellsUterine receptivityAbnormal cytokineAnimal modelsEndometrial genesClinical treatmentEmbryo qualityFertility treatmentExact mechanismDisease
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